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2016 (English)In: Journal of Pediatric Gastroenterology and Nutrition - JPGN, ISSN 0277-2116, E-ISSN 1536-4801, Vol. 62, no 3, p. 414-419Article in journal (Refereed)
Abstract [en]
Objectives: The purpose of this randomised study was to compare the
quality of bowel cleansing using either polyethylene glycol (PEG) or sodium
picosulphate (NaPico) (primary outcome) in relation to the tolerability and
acceptance of these laxatives among children and their caregivers (secondary
outcome).
Methods: The study was a randomised controlled trial that was conducted as
an investigator-blinded study within the Department of Paediatrics of Ska°ne
University Hospital in Malmo¨ , Sweden. A total of 72 children (10–18 years
of age) were randomly placed into 1 of 2 groups (PEG or NaPico). The Ottawa Bowel Preparation Quality Score was used to evaluate the quality of bowel cleansing. A total of 2 different questionnaires were used to evaluate both the acceptability and tolerability of the laxatives.
Results: In total, 71 children completed the bowel cleansing. Of these 71 cleanses, 67 protocols were analysed according to the Ottawa Bowel Preparation Quality Score. No significant difference in bowel cleansing quality was detected between the 2 groups. Rates of acceptability and tolerability were significantly higher in the NaPico group than in the PEG group.
Conclusions: In the present study, both laxatives were found to be satisfactory in terms of aiding the performance of an uncomplicated and successful colonoscopy. NaPico was, however, more tolerable to the children than PEG, and both, the children and their caregivers, were more accepting of NaPico than of PEG. Consequently, NaPico can be
recommended as the option for bowel cleansing in children ages 10 years and older.
Key Words: bowel cleansing, children, colonoscopy, randomised controlled trial
Place, publisher, year, edition, pages
Lamy, Wolters Kluwer, 2016
Keywords
bowel cleansing, children, colonoscopy, randomised controlled trial
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:mau:diva-14897 (URN)10.1097/MPG.0000000000000978 (DOI)000371304000015 ()26360658 (PubMedID)2-s2.0-84959876546 (Scopus ID)21901 (Local ID)21901 (Archive number)21901 (OAI)
2020-03-302020-03-302024-06-17Bibliographically approved