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  • 1.
    Alrebdi, Abdulaziz
    et al.
    Qassim Univ, Coll Dent, Dept Conservat Dent, Buraydah, Saudi Arabia..
    Ericson, Dan
    Malmö universitet, Odontologiska fakulteten (OD).
    Qasim, Syed Saad B.
    Kuwait Univ, Fac Dent, Dept Bioclin Sci, Jabriya, Kuwait.;Univ Oslo, Inst Clin Dent, Dept Biomat, Oslo, Norway..
    Albahoth, Ahmad
    Qassim Univ, AlRass Dent Coll, Buraydah, Saudi Arabia..
    Al-Sulimani, Abdulelah
    Taif Univ, Coll Dent, Restorat Dept, At Taif, Saudi Arabia..
    Baskaradoss, Jagan Kumar
    Kuwait Univ, Fac Dent, Dept Dev & Prevent Sci, Div Dent Publ Hlth, Jabriya, Kuwait..
    Efficacy of fluoride varnish in treating orthodontically-induced white spot lesions: a systematic review and meta-analysis2021Ingår i: Australasian Orthodontic Journal, ISSN 2207-7472, Vol. 37, nr 2, s. 147-156Artikel, forskningsöversikt (Refereegranskat)
    Abstract [en]

    Objectives: To systematically review the effectiveness of 5% sodium fluoride varnish (FV) in the treatment of orthodontically-induced white spot lesions (WSLs). Methods: A literature search of three independent databases (Medline, Cochrane Library and Web of Science) was performed from inception to November 2020. This systematic review included randomised/quasi-randomised clinical trials (RCTs) that used FV for patients who had at least one WSL as a result of fixed orthodontic treatment. Exclusion criteria were split-mouth study designs or studies that failed to report WSLs as the outcome variable or studies with less than 3 months follow-up. An Inverse Variance fixed-effect method was performed for continuous variables. Changes in the mean difference (MD) for the DIAGNOdent (DD) scores following FV application were calculated at the 95% confidence interval (CI). Results: Three of the four included studies showed significant improvement in the remineralisation of WSL after treatment with FV in comparison to control subjects. Three studies were conducted on patients after fixed orthodontic treatment and one study was conducted during treatment. The studies included a total of 284 participants with the majority in the age range of 10 to 25 years. The distribution of the participants was approximately equal in the FV and control group. When compared with the control group, there was a statistically significant reduction in the mean DD readings for the FV group at the 3-month (MD=-3.43; 95% CI:-4.72 to-2.15; p < 0.001) and at the 6-month (MD =-4.47; 95% CI:-4.72 to-2.15; p < 0.001) follow-up visit. Conclusions: Although few studies have shown the effectiveness of FV application in the treatment of orthodontically-induced WSLs, the limited number of robust clinical trials, makes it difficult to draw a definitive conclusion. (Aust Orthod J 2021; 37: 147 156. DOI: 10.21307/aoj-2021-016)

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  • 2.
    Alsuhaibani, Fatimah
    et al.
    Department of Restorative Dentistry, College of Dentistry, Qassim University, Buraydah, Saudi Arabia.
    Alsuhaibani, Abdulaziz
    Department of General Surgery, King Saud Medical City, Riyadh, Saudi Arabia.
    Ericson, Dan
    Malmö universitet, Odontologiska fakulteten (OD).
    Larsson, Kerstin
    Malmö universitet, Odontologiska fakulteten (OD).
    Risk Factors for Dental Erosion After Bariatric Surgery: A Patient Survey2021Ingår i: International Dental Journal, ISSN 0020-6539, E-ISSN 1875-595X, Vol. 72, nr 4, s. 491-498, artikel-id S0020-6539(21)00251-3Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    INTRODUCTION: Treatment of obesity by bariatric surgery has increased in recent years. Reported side effects that may predispose to dental erosion include reflux, vomiting, and an increased frequency of intake of food and drink.

    OBJECTIVE: The aim was to investigate long-term dietary behaviour and experiences related to symptoms of dental erosion at least 5 years after bariatric surgery.

    METHODS: An online questionnaire study was conducted amongst 250 patients who had undergone bariatric surgery at King Saud Medical City in Saudi Arabia 5 years ago or more. It comprised 36 questions on demographic data, dietary habits, general health, dental health, and oral symptoms. The data were analysed using Chi-square and sign tests (significance level P < .05).

    RESULTS: A significant increase in acidic reflux and vomiting was found after bariatric surgery and appeared to increase with time after surgery. Also, a significant association between presence of acidic reflux and symptoms of dental erosion was found. However, 68.5% reported improved overall well-being after surgery. The response rate was 21.6% (most were female, aged 30-59 years). Respondents were generally not advised to visit a dentist in connection with bariatric surgery.

    CONCLUSIONS: This long-term cross-sectional study suggests a time-dependent, increasing occurrence of vomiting and acidic reflux after bariatric surgery. Vomiting and reflux became even more common after 5 to 10 years. A significant relationship emerged between a high frequency of acidic reflux and a high frequency of oral symptoms related to dental erosion. Daily occurrence of general symptoms related to dumping syndrome were reported by the majority. However, in a 5- to 10-year perspective, general symptoms related to dumping syndrome and symptoms from dental erosion did not seem to detract from the respondents' overall satisfaction with daily living. Oral health problems might be reduced if patients who had bariatric surgery were referred to a dentist for prevention and monitoring.

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  • 3. Bjørndal, Lars
    et al.
    Reit, Claes
    Bruun, Gitte
    Markvart, Merete
    Kjældgaard, Marianne
    Näsman, Peggy
    Thordrup, Marianne
    Dige, Irene
    Nyvad, Bente
    Fransson, Helena
    Malmö högskola, Odontologiska fakulteten (OD).
    Lager, Anders
    Malmö högskola, Odontologiska fakulteten (OD).
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Petersson, Kerstin
    Malmö högskola, Odontologiska fakulteten (OD).
    Olsson, Jadranka
    Santimano, Eva M
    Wennström, Anette
    Winkel, Per
    Gluud, Christian
    Treatment of deep caries lesions in adults: randomized clinical trials comparing stepwise vs. direct complete excavation, and direct pulp capping vs. partial pulpotomy2010Ingår i: European Journal of Oral Sciences, ISSN 0909-8836, E-ISSN 1600-0722, Vol. 118, nr 3, s. 290-297Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Less invasive excavation methods have been suggested for deep caries lesions. We tested the effects of stepwise vs. direct complete excavation, 1 yr after the procedure had been carried out, in 314 adults (from six centres) who had received treatment of a tooth with deep caries. The teeth had caries lesions involving 75% or more of the dentin and were centrally randomized to stepwise or direct complete excavation. Stepwise excavation resulted in fewer pulp exposures compared with direct complete excavation [difference: 11.4%, 95% confidence interval (CI) (1.2; 21.3)]. At 1 yr of follow-up, there was a statistically significantly higher success rate with stepwise excavation, with success being defined as an unexposed pulp with sustained pulp vitality without apical radiolucency [difference: 11.7%, 95% CI (0.5; 22.5)]. In a subsequent nested trial, 58 patients with exposed pulps were randomized to direct capping or partial pulpotomy. We found no significant difference in pulp vitality without apical radiolucency between the two capping procedures after more than 1 yr [31.8% and 34.5%; difference: 2.7%, 95% CI ()22.7; 26.6)]. In conclusion, stepwise excavation decreases the risk of pulp exposure compared with direct complete excavation. In view of the poor prognosis of vital pulp treatment, a stepwise excavation approach for managing deep caries lesions is recommended.

  • 4. Borg, Ann-Christine
    et al.
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Zimmerman, Mikael
    Missbruk - syns det i munnen?2000Bok (Övrigt vetenskapligt)
    Abstract [sv]

    Tandvårdspersonal kommer idag allt oftare i kontakt med olika typer av missbruk. Boken är en tydlig och systematisk sammanställning över olika former av missbruk, där de kända orala effekterna beskrivs. Även s.k. ätstörningar och matmissbruk redovisas. Boken är rikligt illustrerad, och innehåller många hänvisningar för fördjupning. (Beskrivning från förlaget)

  • 5. Bornstein, Rolf
    et al.
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Future perspectives2001Ingår i: Tissue preservation in caries treatment, Quintessence Publishing Group , 2001, s. 347-355Kapitel i bok, del av antologi (Övrigt vetenskapligt)
  • 6.
    Braathen, Gabriella
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Ingildsen, Viktor
    Malmö högskola, Odontologiska fakulteten (OD). Department of Cariology, Faculty of Odontology, Malmö University, Carl Gustafs väg 34, 214 21 Malmö, Sweden.
    Twetman, Svante
    Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Nørre Allé 20, 2200 Copenhagen N, Denmark.
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Jørgensen, Mette
    Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Nørre Allé 20, 2200 Copenhagen N, Denmark.
    Presence of Lactobacillus reuteri in saliva coincide with higher salivary IgA in young adults after intake of probiotic lozenges2017Ingår i: Beneficial Microbes, ISSN 1876-2883, E-ISSN 1876-2891, Vol. 8, nr 1, s. 17-22Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The aim of this study was to compare the concentration of salivary immunoglobulin A (IgA) and the selected interleukins (IL)-1β, IL-6, IL-8 and IL-10 in young individuals with presence and non-presence of Lactobacillus reuteri in saliva after a three-week intervention with probiotic lozenges. The study group consisted of 47 healthy individuals aged 18-32 years with no clinical signs of oral inflammation. In a randomised, double-blind, placebo-controlled, cross-over trial participants ingested two lozenges per day containing two strains of the probiotic bacterium L. reuteri or placebo lozenges. The intervention and wash-out periods were three weeks. Stimulated and unstimulated whole saliva was collected at baseline and immediately after termination of the intervention periods. The samples were analysed for total protein, salivary IgA and selected cytokines. In this extended analysis, data were collected by analysing baseline and follow-up saliva samples related to ingestion of the probiotic lozenges for the presence of L. reuteri through DNA-extraction, PCR-amplification and gel-electrophoresis. At baseline, 27% of the individuals displayed presence of L. reuteri and 42% were positive immediately after the three-week probiotic intervention. Individuals with presence of L. reuteri in saliva had significantly higher (P<0.05) concentrations of salivary IgA and %IgA/protein at the termination of the probiotic intake compared with non-presence. No differences in the cytokine levels were observed. In conclusion, detectable levels of L. reuteri in saliva coincided with higher concentrations of salivary IgA and %IgA/protein in stimulated whole saliva after the three-week daily intake of probiotic lozenges. Our findings suggest that monitoring the presence of probiotic candidates in the oral environment is important to interpret and understand their possible immune-modulating role in maintaining oral health.

  • 7.
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    A perspective on MID2007Ingår i: Dental products report Asia Pacific : DPR Asia Pacific, ISSN 1753-8092, nr 1, s. 30-30Artikel i tidskrift (Övrig (populärvetenskap, debatt, mm))
  • 8.
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Chemical and mechanical dental caries removing system Carisolv1999Ingår i: Shikai tenbo (Dental outlook), ISSN 0011-8702, Vol. 93, nr 3, s. 513-533Artikel i tidskrift (Refereegranskat)
  • 9.
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Färdiglagat?2008Ingår i: Tandhygienisttidningen, ISSN 1102-6146, nr 4, s. 36-41Artikel i tidskrift (Övrigt vetenskapligt)
    Abstract [sv]

    Det finns fortfarande mycket karies i världen som behöver lagas. Orsakerna till karies är forfarande att bakterier i plack (i biofilmen) kan förjäsa socker till syror. Så färdiglagat är det inte på långa vägar. Men hur går det egentligen med en lagad tand? Hur länge håller det? Lönar det sig att laga tänder?

  • 10.
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Karies2011Ingår i: Nationella riktlinjer för vuxentandvård 2011: vetenskapligt underlag, Socialstyrelsen , 2011, s. 40-221Kapitel i bok, del av antologi (Övrigt vetenskapligt)
    Abstract [sv]

    Detta vetenskapliga underlag utgör kunskapsunderlag för de rekommenda-tioner som Socialstyrelsen ger i Nationella riktlinjer för vuxentandvård 2011. Underlaget hör samman med Nationella riktlinjer för vuxentandvård – stöd för styrning och ledning. Vi framför vårt varma tack till alla de som med stort engagemang och ex-pertkunnande har medverkat i att ta fram det vetenskapliga underlaget för Nationella riktlinjer för vuxentandvård.

  • 11.
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Minimally invasive dentistry2003Ingår i: Oral Health & Preventive Dentistry, ISSN 1602-1622, E-ISSN 1757-9996, Vol. 1, nr 2, s. 91-92Artikel i tidskrift (Övrig (populärvetenskap, debatt, mm))
  • 12.
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Minimally Invasive Dentistry - Philosophy and Motives in Cariology2004Ingår i: Nordic Dentistry Yearbook, Quintessence , 2004, s. 49-65Kapitel i bok, del av antologi (Övrigt vetenskapligt)
  • 13.
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    The concept of minimally invasive dentistry2007Ingår i: Dental Update, ISSN 0305-5000, Vol. 34, nr 1, s. 9-18Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    This paper reviews Minimally Invasive Dentistry (MID) from a day-to-day dentistry perspective, focusing mostly on cariology and restorative dentistry, even though it embraces many aspects of dentistry. The concept of MID supports a systematic respect for the original tissue, including diagnosis, risk assessment, preventive treatment, and minimal tissue removal upon restoration. The motivation for MID emerges from the fact that fillings are not permanent and that the main reasons for failure are secondary caries and filling fracture. To address these flaws, there is a need for economical re-routing so that practices can survive on maintaining dental health and not only by operative procedures.

  • 14.
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    The use of Carisolv at a university clinic2001Ingår i: Tissue preservation in caries treatment, Quintessence Publishing Group Ltd , 2001, s. 243-251Kapitel i bok, del av antologi (Övrigt vetenskapligt)
  • 15.
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    The use of tissue-preserving methods: patients perspectives: the average patient2001Ingår i: Tissue preservation in caries treatment, Quintessence Publishing Group , 2001, s. 145-149Kapitel i bok, del av antologi (Övrigt vetenskapligt)
  • 16.
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    What is Minimally Invasive Dentistry?2004Ingår i: Oral Health & Preventive Dentistry, ISSN 1602-1622, E-ISSN 1757-9996, Vol. 2, nr Suppl 1, s. 287-292Artikel i tidskrift (Övrigt vetenskapligt)
    Abstract [en]

    Minimally Invasive Dentistry is the application of "a systematic respect for the original tissue." This implies that the dental profession recognizes that an artifact is of less biological value than the original healthy tissue. Minimally invasive dentistry is a concept that can embrace all aspects of the profession. The common delineator is tissue preservation, preferably by preventing disease from occurring and intercepting its progress, but also removing and replacing with as little tissue loss as possible. It does not suggest that we make small fillings to restore incipient lesions or surgically remove impacted third molars without symptoms as routine procedures. The introduction of predictable adhesive technologies has led to a giant leap in interest in minimally invasive dentistry. The concept bridges the traditional gap between prevention and surgical procedures, which is just what dentistry needs today. The evidence-base for survival of restorations clearly indicates that restoring teeth is a temporary palliative measure that is doomed to fail if the disease that caused the condition is not addressed properly. Today, the means, motives and opportunities for minimally invasive dentistry are at hand, but incentives are definitely lacking. Patients and third parties seem to be convinced that the only things that count are replacements. Namely, they are prepared to pay for a filling but not for a procedure that can help avoid having one.

  • 17.
    Ericson, Dan
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Barata, TJE
    Bresciani, E
    Fagundes, TC
    Mattos, MCR
    Lauris, JRP
    Navarro, MFL
    Clinical evaluation of two minimal interventional restorative approaches: 5-year follow-up2007Konferensbidrag (Refereegranskat)
    Abstract [en]

    Objective: To compare the performance of two minimally invasive restorative treatment approaches for managing dental caries. Methods: A total of 50 pregnant women (second trimester of pregnancy), mean age 22±5.30 years, were treated by two previously trained operators. The treatment approaches tested were: chemo-mechanical (Carisolv-MediTeam, Sweden) and mechanical (Atraumatic Restorative Treatment -ART) methods. A parallel-group study design was used in which the two treatments were randomly placed in 50 matched pairs of permanent teeth. The treatments were performed in Public Health Centers located in suburban areas of Bauru city in Brazil. The restorative material used was high strength glass ionomer cement (Ketac Molar, 3M ESPE).The restorations were evaluated by 2 calibrated independent double-blind examiners according to ART criteria. The inter examiner kappa was 0.93. The data were analyzed using 95% confidence interval on the binomial distribution and Fisher Exact test. A difference was statistically significant if p<0.05. Results: In a 5-year follow-up, 34% of the restorations were evaluated. In the chemo-mechanical group 53% (CI=27-77%) of the restorations were considered as successful and in the mechanical group 60% (CI=33-83%). There was no statistically significant difference between the 5-year success rate for both groups (p=0.73). Conclusion: The two minimal interventional restorative approaches showed similar clinical performance after 5 years.

  • 18.
    Ericson, Dan
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Bornstein, Rolf
    Development of a tissue-preserving agent for caries removal2001Ingår i: Tissue Preservation in Caries Treatment, Quintessence Publishing (IL) , 2001, s. 153-156Kapitel i bok, del av antologi (Övrigt vetenskapligt)
    Abstract [en]

    Show synopsis This work provides information on contemporary international developments in minimal tissue intervention methods, including the use of fluoride, ozone and mild chemical treatments. In particular, the safety and efficacy of a novel chemomechanical agent, Carisolv, is described. In addition, the text describes future trends in caries treatment, including a discussion about the possibility of using DNA chip analyses in dentistry

  • 19.
    Ericson, Dan
    et al.
    Malmö universitet, Odontologiska fakulteten (OD).
    Carlsson, Peter
    Malmö universitet, Odontologiska fakulteten (OD).
    Gabre, Pia
    Institute of Odontology The Sahlgrenska Academy of Gothenburg Gothenburg Sweden.
    Wårdh, Inger
    Department of dental medicine and Academic centre for geriatric dentistry, Karolinska institutet, Stockholm and Department of health sciences University of Karlstad Karlstad Sweden.
    Zimmerman, Mikael
    Ad Modum AB Hässleholm Sweden.
    Sjögren, Petteri
    Oral Care AB Stockholm Sweden.
    Effect of a single application of silver diamine fluoride on root caries after 12 months in institutionalised older adults: A randomised clinical trial2023Ingår i: Gerodontology, ISSN 0734-0664, E-ISSN 1741-2358, Vol. 40, nr 3, s. 390-397Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objective: Silver diamine fluoride (SDF) has been shown to be highly effective against caries, in particular for arresting root surface caries and for dentine caries in primary teeth. SDF may complement fluoride varnish routines for treatment of root caries in nursing home residents. The aim of this randomised, single-blinded, placebo-controlled trial was to evaluate the additive effect of a single annual application of SDF for prevention and treatment of incipient root caries in older adult nursing home residents.

    Method: Four hundred older adult nursing home residents (≥70 years old) with at least one exposed root surface (on teeth 15, 14, 13, 23, 24, or 25) were identified during routine dental examination visits in the domiciliary dental care setting. Eligible patients, who were able to understand the implication of consenting to the study, were invited to participate. Their cleaned root surfaces were randomly allocated to treatment with SDF (Advantage Arrest Silver Diamine Fluoride 38%, Advantage Arrest, LLC, Redmond, OR 97756, USA, Lot 16 152) or with placebo (tap water), each for 1 minute.

    Results: Of the 400 eligible individuals, 42 declined to participate and two forms were destroyed. The remaining 356 participants (89.0%; mean age 87.7 years) were randomly allocated, with 174 going to the SDF group and 182 to the placebo group. At 1 year, 273 participants (76.7%) were available for assessment: 135 in the SDF group and 138 in the placebo group. By that time, 109 individuals (39.9%) demonstrated root caries progression or regression. Among those 118 (16.7%) of the 708 included root surfaces had developed caries There were no statistically significant differences in the primary outcome related to treatment with SDF or placebo, at either patient or root surface level.

    Conclusion: Based on the finding of this clinical trial, it is concluded that a single SDF application to complement a risk-based preventive programme including fluoride varnish applications did not have a statistically significant additional preventive effect on root caries development in a group of older adult nursing home residents with limited caries activity and cognitive capacity to cooperate in oral care activities.

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  • 20.
    Ericson, Dan
    et al.
    Malmö universitet, Odontologiska fakulteten (OD).
    Carlsson, Peter
    Malmö universitet, Odontologiska fakulteten (OD).
    Gabre, Pia
    Institute of Odontology, The Sahlgrenska Academy of Gothenburg, Göteborg, Sweden.
    Wårdh, Inger
    Department of Dental Medicine and Academic Centre for Geriatric Dentistry, Karolinska Institutet, Stockholm and Department of Health Sciences, University of Karlstad, Karlstad, Sweden.
    Zimmerman, Mikael
    Ad Modum AB, Hässleholm, Sweden.
    Sjögren, Petteri
    Oral Care AB, Stockholm, Sweden.
    Response to professor Milgrom.2023Ingår i: Gerodontology, ISSN 0734-0664, E-ISSN 1741-2358, Vol. 40, nr 3, s. 407-407Artikel i tidskrift (Övrigt vetenskapligt)
  • 21.
    Ericson, Dan
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Carlsson, Peter
    Malmö högskola, Odontologiska fakulteten (OD).
    Songpaisan, Yupin
    Ellen, Richard P
    The legacy of cariologist Douglas Bratthall, an inspired scientist2012Ingår i: Journal of Dental Research, ISSN 0022-0345, E-ISSN 1544-0591, Vol. 91, nr 10, s. 909-913Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Douglas Bratthall was an inspirational cariologist known for his playful curiosity, thoughtful inquisitiveness, incisive scholarship, and energetic leadership. He became a time, mind, and global traveler who viewed his career path as an exotic safari. This 'Discovery!' report identifies where his era's burning issues have led and how they were shaped by his contributions.

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  • 22.
    Ericson, Dan
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Hamberg, Kristina
    Malmö högskola, Odontologiska fakulteten (OD).
    Bratthall, Gunilla
    Malmö högskola, Odontologiska fakulteten (OD).
    Sinkiewicz-Enggren, Gabriela
    Malmö högskola, Fakulteten för hälsa och samhälle (HS), Institutionen för biomedicinsk vetenskap (BMV).
    Ljunggren, Lennart
    Malmö högskola, Fakulteten för hälsa och samhälle (HS), Institutionen för biomedicinsk vetenskap (BMV).
    Salivary IgA response to probiotic bacteria and mutans streptococci after the use of chewing gum containing Lactobacillus reuteri2013Ingår i: Pathogens and Disease, E-ISSN 2049-632X, Vol. 68, nr 3, s. 82-87Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    We investigated whether ingestion of probiotic bacteria could influence salivary IgA levels, specific anti-mutans streptococci IgA levels and specific antibodies towards the ingested probiotic bacterium. The study was a randomised, double-blind, placebo-controlled trial, where the test group (n = 11) received twice daily chewing of gum containing Lactobacillus reuteri (2 9 108 CFU per dose) and the control group (n = 12) received placebo. Resting saliva was collected before and after 12 weeks of treatment and 4 weeks after end of treatment. Total salivary IgA concentrations were measured by ELISA. Specific IgA reactivity was determined using a whole-cell ELISA. Results were expressed as % IgA per protein in saliva. The level of total IgA% per protein increased significantly between pretreatment levels (13.5%) and follow-up treatment levels (14.4%) within the test group only (P < 0.05). No changes were seen in the control group during the trial. The level of probiotic-reactive antibodies decreased significantly between pre- and post-treatment samples (from 12.2% to 9.0%, P < 0.05) in the test group. Similarly, the level of specific mutans streptococci antibodies decreased significantly between pre- and post-treatment samples (P < 0.05) in the test group only (for Streptococcus mutans from 20.1% to 15.0%; for Streptococcus sobrinus from 7.4% to 5.3%). Ingestion of probiotic bacteria might influence the adaptive immune response of the host.

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  • 23.
    Ericson, Dan
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Kidd, E
    McComb, D
    Mjör, I
    Noack, M
    Minimally invasive dentistry: concepts and techniques in cariology2003Ingår i: Oral Health & Preventive Dentistry, ISSN 1602-1622, E-ISSN 1757-9996, Vol. 1, nr 1, s. 59-72Artikel i tidskrift (Övrigt vetenskapligt)
    Abstract [en]

    The concept ‘Minimally Invasive Dentistry’ can be defined as maximal preservation of healthy dental structures. Within cariology, this concept includes the use of all available information and techniques ranging from accurate diagnosis of caries, caries risk assessment and prevention, to technical procedures in repairing restorations. Dentists are currently spending more than half their time replacing old restorations. The main reasons for restoration failures are secondary caries and fractures, factors that are generally not addressed in the technical process of replacing a restoration. Prevailing concepts on minimally invasive dentistry seem to be ‘product or technique-motivated’, challenging one technique or product with another, rather than focusing on a general concept. New knowledge of caries progression rates has also led to substantial modification of restorative intervention thresholds and further handling of the disease. New diagnostic tools for caries lesion detection, caries risk assessment and focused preventive treatments have decreased the need for early restorative interventions. In parallel to this, new techniques for cutting teeth and removing decay have evolved. This paper focuses on describing minimally invasive dentistry in cariology from a conceptual perspective, relating to clinical caries diagnosis, restorative intervention thresholds and operative procedures, with special reference to survival of tunnel and slot restorations and to repair vs. replacement of defective restorations.

  • 24.
    Ericson, Dan
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Tjäderhane, Leo
    Gjerdet, Nils Roar
    Hörsted-Bindslev, Preben
    Att restaurera en tand - är det god medicin?2011Ingår i: Tandläkartidningen, ISSN 0039-6982, Vol. 103, nr 1, s. 62-63Artikel i tidskrift (Övrigt vetenskapligt)
  • 25.
    Ericson, Dan
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Tveit, Anne Björg
    Sølv- og tinfluorider i forebyggelse og behandling af caries og erosioner2017Ingår i: Tandlægebladet, ISSN 0039-9353, Vol. 121, nr 6, s. 246-248Artikel, forskningsöversikt (Refereegranskat)
    Abstract [en]

    Silver and stannous fluorides in prevention and treatment of caries and tooth erosions Caries and dental erosions involve major challenges in dentistry. In addition to removal of causal factors (sugars and acids), in the man-agement of those conditions, silver and tin (stannous) fluorides have recently received much attention. Silver diamine fluoride has proved effective for arresting and prevention caries. Stannous fluoride has been of particular interest in the prevention of dental erosions. This paper provides an overview of proposed mechanisms of action and available data on clinical effectiveness for these two metal fluorides.

  • 26.
    Ericson, Dan
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Örstavik, Dag
    Cariological and Endodontic Aspects2013Ingår i: Textbook of Fixed Prosthodontics: the Scandinavian Approach / [ed] Christer Nilner, Stig Carlsson, Bjørn L Dahl, Gothia Förlag AB, 2013, s. 796-798Kapitel i bok, del av antologi (Övrigt vetenskapligt)
  • 27.
    Furundzic, Kristina
    et al.
    SkSne County Public Dental Service, MalmO, Sweden.
    Malmberg, Joy
    Malmö universitet, Odontologiska fakulteten (OD). Skåne County Public Dental Service, Trelleborg, Sweden.
    Sandström, Boel
    Department of Health, Bleklnge Institute of Technology, Karlskrona, Sweden.
    Ericson, Dan
    Malmö universitet, Odontologiska fakulteten (OD).
    Why Do Adolescents Use Fluoride Toothpaste?: A Qualitative Interview Investigation2020Ingår i: Oral Health & Preventive Dentistry, ISSN 1602-1622, E-ISSN 1757-9996, Vol. 18, nr 3, s. 441-446Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Purpose: Fluoride toothpastes are effective in caries prevention. In legislation, regular fluoride toothpaste is a cosmetic product; adolescents use it for aesthetic purposes. In dentistry, fluoride toothpaste is considered a caries preventive drug recommended to patients for that reason. Knowledge is lacking concerning what motivates adolescents to use fluoride toothpaste. Dental professionals need to understand how to motivate a risk-group for caries development to use fluoride toothpaste frequently in order to effectively motivate patients to prevent tooth decay. The purpose of this study was to investigate what motivates adolescents to use fluoride toothpaste. Materials and Methods: The study was conducted at a high school in southern Sweden. The final sample consisted of 16 adolescents age 16 to 19. This study employed a qualitative design using semi-structured interviews. The data were analysed using manifest content analysis with an occasional inductive approach. Results: Reasons for why adolescents use fluoride toothpaste were found in four different categories: oral health, economy, upbringing and habit, social influences. Conclusion: There are reasons to believe that dental professionals might have missed important arguments for why adolescents use fluoride toothpaste. The participants mentioned oral health and aesthetics as important reasons for using fluoride toothpaste, as well as other more surprising factors such as financial reasons and social environment. There are thus more arguments for using fluoride toothpaste that adolescents value than the ones we believe dental professionals use.

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  • 28.
    Götrick, Bengt
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Åkerman, Sigvard
    Malmö högskola, Odontologiska fakulteten (OD).
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Torstenson, R
    Tobin, Gunnar
    Oral pilocarpine for treatment of opioid-induced oral dryness in healthy adults2004Ingår i: Journal of Dental Research, ISSN 0022-0345, E-ISSN 1544-0591, Vol. 83, nr 5, s. 393-397Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Pilocarpine induces a profuse flow of saliva when administered orally, but effects on drug-induced oral dryness have not been examined. The aim of this trial was to investigate if pilocarpine increases production of saliva in individuals suffering from dry mouth due to treatment with opioids. Sixtyfive individuals were enrolled in a randomized, double-blind, placebo-controlled trial. The subjects received tramadol (50 mg t.d.s.) to induce oral dryness, and were thereafter assigned to one of three groups. Secretion rate of saliva was measured before and after tramadol, and after the oral administration of pilocarpine (5 mg), placebo, or no treatment. Baseline characteristics did not differ among the groups (mean ± SEM: 0.37 ± 0.06 mL/min), and tramadol lowered the secretion at the same level in all groups (0.15 ± 0.02 mL/min). Pilocarpine increased the flow above that observed with placebo (0.66 ± 0.19 vs. 0.15 ± 0.02 mL/min). Thus, pilocarpine re-establishes the flow of saliva in the state of tramadol-induced oral dryness.

  • 29. Hansson, Bengt Olof
    et al.
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Karies- sjukdom och hål2003Bok (Övrigt vetenskapligt)
  • 30. Hansson, Bengt Olof
    et al.
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Karies: sjukdom och hål2008Bok (Övrigt vetenskapligt)
  • 31. Hatherell, S
    et al.
    Lynch, Christopher D
    Burke, Francis M
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Gilmour, Alan SM
    Attitudes of final-year dental students to bleaching of vital and non-vital teeth in Cardiff, Cork, and Malmö2011Ingår i: Journal of Oral Rehabilitation, E-ISSN 1365-2842, Vol. 38, nr 4, s. 263-269Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The aim of this study was to determine attitudes of final-year dental students in Cardiff, Cork and Malmö towards tooth whitening. Following receipt of ethical approval, pre-piloted questionnaires were distributed to final-year dental students in Cork, Cardiff, and Malmö as close as possible to graduation. The questionnaire sought information relating to various opinions and attitudes towards the use of bleaching techniques including safety of bleaching, confidence in the provision of bleaching, recommendations to patients, teaching received, awareness of restrictions on the use of bleaching products and management of simulated clinical scenarios. Eighty three per cent (n = 116) of questionnaires were returned. Cork dental students had the most didactic teaching (2- h vital, 1- h non-vital bleaching) compared to Cardiff or Malmö students (0 h each). More Cork students regarded bleaching as safe (76%, n = 28) than Cardiff (70%, n = 32) or Malmö (36%, n = 12) students. More than 50% of Cork students feel they know enough about bleaching to provide it in practice, significantly more than Cardiff (<25%) or Malmö (<25%) students. The majority of students would provide vital bleaching after qualification (100% (n = 37) Cork; 82% (n = 27) Malmö; 76% (n = 35) Cardiff). In simulated clinical scenarios, more Cork students would propose bleaching treatments (89%n = 33) than Malmö (64%n = 21) or Cardiff (48%n = 22) students. Variations exist in the attitudes and approaches of three European dental schools towards bleaching. Dental students need to be best prepared to meet the needs of their future patients.

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  • 32. Hedenbjörk Lager, Anders
    et al.
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Aciduric Bacterial Communities at Three Levels in Dentin Caries2013Ingår i: Oral Health & Preventive Dentistry, ISSN 1602-1622, E-ISSN 1757-9996, Vol. 11, nr 4, s. 359-367Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Purpose: Dentin caries constitute a complex ecosystem with a diverse microbiota adapted to fluctuations in nutrient concentration and acidity. However, knowledge about the acid tolerant microbiota at different levels in the lesion is rather poor. Hence, the purpose of this study was to investigate the acid tolerant microflora at different levels in established dentin caries lesions using solid pH-selective media. Materials and Methods: Primary dentin caries lesions were sampled with a bur at three levels (superficial, centre and the clinically caries-free floor of the lesion) in 10 patients. Samples were incubated on pH-neutral and pH-selective (pH 4.0, 4.5, 5.0, 5.5) agars. Numbers of colony-forming units (cfu) were determined and colonies were subsequently characterised morphologically and isolated. Results: The total number of bacteria in the carious lesions, recovered using blood agar (BA), ranged from 5.88 x 103 to 5.85 x 105 (median 2.64 x 105; range 5.80 x 105) and numbers of recovered bacteria decreased with decreasing agar pH. Fewer bacteria were found in the clinically caries-free dentin (P = 0.042), but the mean number of cfu (BA) was still 5.88 x 103 in those samples. Conclusion: Each of the 10 investigated dentin caries lesions harboured a unique microbial flora, indicating that various combinations of aciduric bacteria can colonise, survive in and probably propagate dentin caries. Solid pH-selective agars can be used successfully to select acid-tolerant microorganisms in dentin caries lesions. This could be used to describe this subset of the total microbiome from a phenotypic point of view, an objective that cannot be accomplished using molecular methods.

  • 33.
    Hedenbjörk-Lager, Anders
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Bjørndal, Lars
    Gustafsson, Anders
    Sorsa, Timo
    Tjäderhane, Leo
    Åkerman, Sigvard
    Malmö högskola, Odontologiska fakulteten (OD).
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Caries correlates strongly with salivary levels of Matrix Metalloproteinase-82015Ingår i: Caries Research, ISSN 0008-6568, E-ISSN 1421-976X, Vol. 49, nr 1, s. 1-8, artikel-id 49Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The caries process in dentin involves the degradation of both mineral and organic matrix. The demineralization has been demonstrated to be caused by bacterial acids. How-ever, the collagen degradation is considered to be initiated by endogenous proteolytic enzymes, mainly collagenolytic matrix metalloproteinases (MMPs). This paper aims to relate salivary MMP-8 (or salivary collagenase-2) and tissue inhibi-tor of MMP (TIMP-1) levels to manifest caries in a large num-ber of subjects. A random sample of 451 adults (aged 18-87 years) living in the south of Sweden was included in this study. Standard clinical examinations were performed, and stimulated saliva was collected and analyzed for concentra-tions of MMP-8, TIMP-1 and total protein, using an immuno-fluorometric assay, an enzyme-linked immunosorbent assay and the Bradford assay, respectively. Salivary numbers of mutans streptococci and lactobacilli were determined using a chair-side kit. Subjects with manifest caries lesions present-ed with elevated levels of MMP-8 (p < 0.001) as well as total protein, MMP-8/TIMP-1 ratio, bleeding on probing and plaque index (p = 0.05) compared with subjects without manifest caries. Multiple linear regression analysis with car-ies as the dependent variable revealed MMP-8 as the only significant explanatory variable (p < 0.001). TIMP-1 was not significant in any case. Using MMP-8 as the dependent vari-able revealed total protein concentration, caries lesions (p ≤ 0.001) and salivary secretion rate (p = 0.05) as explanatory variables. In conclusion, our data reveal that subjects with manifest caries lesions have elevated levels of salivary MMP-8 relative to subjects with no caries lesions.

  • 34.
    Hedenbjörk-Lager, Anders
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Hamberg, Kristina
    Malmö högskola, Odontologiska fakulteten (OD).
    Pääkkönen, Virve
    Research Unit of Oral Health Sciences, University of Oulu, Oulu, Finland.
    Tjäderhane, Leo
    Research Unit of Oral Health Sciences, University of Oulu, Oulu, Finland; Medical Research Center, Oulu University Hospital, University of Oulu, Finland; Department of Oral and Maxillofacial Diseases, University of Helsinki, Helsinki University Hospital, Helsinki, Finland.
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Collagen degradation and preservation of MMP-8 activity in human dentine matrix after demineralization2016Ingår i: Archives of Oral Biology, ISSN 0003-9969, E-ISSN 1879-1506, Vol. 68, s. 66-72Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    OBJECTIVE: Dental caries is a process driven by acids produced by oral microorganisms followed by degradation of the dentine collagen matrix by proteolytic enzymes. Matrix metalloproteinases (MMPs) have been suggested to contribute to caries by degrading collagen. The aim of this study was to develop a method for generating demineralized dentine matrix substrate (DDM) maintaining MMP-8 bioactivity and no interference with later assays. Such a substrate would allow study of the effects of various treatments on MMP-8 activity and collagen degradation in demineralized dentine. DESIGN: Human dentine was powderized in a tissue grinder and frozen (-80°C). The powder was demineralized in dialysis tubes, using EDTA or acetic acid. The demineralized dentine matrix (DDM) was harvested and analyzed for collagen content using SDS-PAGE. The DDM was subsequently suspended in PBS or TESCA buffer. Protein, MMP-8 (ELISA) and collagen (HYP) was analyzed directly or after 1 wk. RESULTS: EDTA or acid demineralization of dentine using dialysis yielded a substrate rich in collagen coupled with preserved MMP-8 activity. Collagen degraded in room temperature, assessed by higher HYP amounts in the soluble fraction of DDM after one wk, indicating that the methods used preserved active DDM-components after the demineralization process. CONCLUSIONS: The presented demineralization methods both provided insoluble DDM substrates suitable for further intervention studies. However, it was found that the substrates differed depending on the demineralization method and buffers used. This needs further study to find an optimal technique for generating DDM with retained proteins as well as enzymatic bioactivity.

  • 35.
    Hoszek, Anders
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    In vitro fluoride release and the antibacterial effect of glass ionomers containing chlorhexidine gluconate2008Ingår i: Operative dentistry, ISSN 0361-7734, E-ISSN 1559-2863, Vol. 33, nr 6, s. 697-702Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    SUMMARY Fluoride release fromglass-ionomers (GI)may be important for the prevention of secondary caries. The addition of chlorhexidine gluconate (CHX) to glass-ionomer cement (3%) adds an effect that enables it to be used as a varnish for the temporary coating of surfaces at risk for caries. This study investigated the fluoride release pattern and antibacterial effect of such a material. Glassionomer luting cement powder (Aqua-Cem) was mixed with water, 10% CHX or 10% CHX with 11% tartaric acid (TA), respectively, to test specimens (6 * 1.5 mm). After setting, the specimens were immersed in 10 ml deionized water and transferred to new vials after various intervals over a period of two months. The antibacterial effect towards mutans streptococci was assessed using agar diffusion. The fluoride release was measured after two hours and after shifting the specimens to new vials 10 times during the two-month period. The total fluoride release was 69.02, 50.64 and 48.56 μg/cm2 from each specimen in the GI, GI-CHX and the GI-CHX-TA groups, respectively. For two-hour old specimens, the mean inhibition zone was 0, 50, 36 mm2 in the GI, GI-CHX and GICHX- TA groups, respectively, and, after two months, 45 mm2 in the GI-CHX group and 19 mm2 in the GI-CHX-TA group. It can be concluded that the addition of CHX and CHX-TA adds antibacterial properties to GI and the release of fluoride is decreased.

  • 36.
    Hoszek, Anders
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Transient reduction of mutans streptococci on tooth surfaces using a chlorhexidine-containing glass ionomer cement varnish1999Ingår i: Swedish Dental Journal, ISSN 0347-9994, Vol. 23, nr 2-3, s. 97-105Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Chlorhexidine (CHX) has been incorporated in polymer-based varnishes to reduce mutans streptococci (ms) by the sustained release of CHX. Such varnishes often adhere well to teeth initially but are easily peeled off. To be effective, repeated application is necessary. Glass ionomer (GI) cements interacts with tooth minerals to form a stronger bond, and the inherent brittleness of the cement makes it difficult to remove in large fragments. The fluoride content may also reduce demineralisation. The aim of this study was to observe whether ms could be reduced interproximally and in saliva by a single application of a GI cement containing 3.3% CHX gluconate (CHX-GI). After professional tooth cleaning and a mouth rinse for 2 min with 0.2% CHX, the teeth of six subjects were coated with CHX-GI cement. An additional six subjects were treated with a GI cement that did not contain CHX, and seven subjects received professional tooth cleaning only. Ms samples were taken interproximally with the tooth pick method before and after treatment. Interproximal levels were classified according to the number of colony-forming units (c.f.u.) found: 0, 1-20, 21-100, and > 100. Saliva ms were sampled with the Strip Mutans method. After four weeks, the interproximal levels of ms had decreased only in the CHX-GI group (p < 0.05). In this group 9 of 14 highly colonised sites (> 100 c.f.u.) remained reduced throughout this period. In the GI and the untreated group a slight increase of ms interproximally was seen after one week. The interproximal ms scores in all groups approached baseline levels after 8 weeks. There were no significant differences in saliva ms levels between the groups during the test period. GI cement may be a possible vehicle for CHX in reducing ms interproximally.

  • 37.
    Hoszek, Anders
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Struzycka, Isabel
    Department of Conservative Dentistry, Medical Academy, Warsaw, Poland.
    Josefovicz, Agata
    Department of Conservative Dentistry, Medical Academy, Warsaw, Poland.
    Wojcieszek, Danuta
    Department of Conservative Dentistry, Medical Academy, Warsaw, Poland.
    Wierzbicka, Maria
    Department of Conservative Dentistry, Medical Academy, Warsaw, Poland.
    Wretlind, Katarina
    Malmö högskola, Odontologiska fakulteten (OD).
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Chlorhexidine-containing Glass Ionomer Cement. A Clinical Investigation on the Fissure Caries Inhibiting Effect in First Permanent Molars2005Ingår i: Swedish Dental Journal, ISSN 0347-9994, Vol. 29, nr 3, s. 89-96Artikel i tidskrift (Övrigt vetenskapligt)
    Abstract [en]

    Glass ionomer cement with addition of chlorhexidine used as a varnish on tooth surfaces has been shown to reduce the number of inter-proximal mutans streptococci (ms). The effect of a single application of such a varnish containing 2.5% chlorhexidine on occlusal caries development of the first permanent molars on 6-year-old children in a high caries incidence area was investigated. The children were examined according to WHO criteria and 262 children with 2 caries free contralateral molars were selected for treatment. Salivary ms samples were collected using the Strip-mutans (SM) method. After brushing the occlusal surfaces with a toothbrush and pumice in water slurry, rinsing and drying with a cotton roll, glass ionomer cement containing chlorhexidine (GI-CHX) and glass ionomer (GI) were applied randomly with a micro brush and the varnish was covered with occlusal wax. At baseline, the mean defs was 18.18 and DMFS was 0.25 and after one year 18.24 and 0.83 respectively. The salivary ms scores were high or very high (SM 2 and 3) in 85.6% at baseline. At the one-year follow up, the GI-CHX and GI materials could not be detected in the fissures. Also, a large number of fissure sealants had been placed in the molars outside the study protocol; thus 4% of the GI-CHX and GI, and 70% of the untreated were sealed at year one. Overall, there was no significant difference between the caries-reducing effect of GI-CHX and GI, but a trend towards a higher effect was seen for GI-CHX. Excluding the sealed molars the reduction was 74% in the GI-CHX-group, and 71% in the GI-group. Conclusion: Addition of 2.5% chlorhexidine to glass ionomer did not seem to increase the caries-reducing effect of the varnish in this high caries incidence population.

  • 38.
    Hänsel Petersson, Gunnel
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Åkerman, Sigvard
    Malmö högskola, Odontologiska fakulteten (OD).
    Isberg, Per-Erik
    Department of Statistics, Lund University School of Economics and Management, Lund University, Lund, Sweden.
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Comparison of risk assessment based on clinical judgement and Cariogram in addition to patient perceived treatment need2016Ingår i: BMC Oral Health, E-ISSN 1472-6831, Vol. 17, nr 1, artikel-id 13Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND: Predicting future risk for oral diseases, treatment need and prognosis are tasks performed daily in clinical practice. A large variety of methods have been reported, ranging from clinical judgement or "gut feeling" or even patient interviewing, to complex assessments of combinations of known risk factors. In clinical practice, there is an ongoing continuous search for less complicated and more valid tools for risk assessment. There is also a lack of knowledge how different common methods relates to one another. The aim of this study was to investigate if caries risk assessment (CRA) based on clinical judgement and the Cariogram model give similar results. In addition, to assess which factors from clinical status and history agree best with the CRA based on clinical judgement and how the patient's own perception of future oral treatment need correspond with the sum of examiners risk score. METHODS: Clinical examinations were performed on randomly selected individuals 20-89 years old living in Skåne, Sweden. In total, 451 individuals were examined, 51 % women. The clinical examination included caries detection, saliva samples and radiographic examination together with history and a questionnaire. The examiners made a risk classification and the authors made a second risk calculation according to the Cariogram. RESULTS: For those assessed as low risk using the Cariogram 69 % also were assessed as low risk based on clinical judgement. For the other risk groups the agreement was lower. Clinical variables that significantly related to CRA based on clinical judgement were DS (decayed surfaces) and combining DS and incipient lesions, DMFT (decayed, missed, filled teeth), plaque amount, history and soft drink intake. Patients' perception of future oral treatment need correlated to some extent with the sum of examiners risk score. CONCLUSIONS: The main finding was that CRA based on clinical judgement and the Cariogram model gave similar results for the groups that were predicted at low level of future disease, but not so well for the other groups. CRA based on clinical judgement agreed best with the number of DS plus incipient lesions.

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  • 39. Jesus Esteves Barata, Terezinha
    et al.
    Bresciani, Eduardo
    Ribeiro Mattos, Maria Cecília
    Pereira Lauris, José Roberto
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Fidela de Lima Navarro, Maria
    Comparasion of two minimally invasive methods on the longevity of glass ionomer cement restorations: short-term results of a pilot study2008Ingår i: Journal of Applied Oral Science, ISSN 1678-7757, E-ISSN 1678-7765, Vol. 16, nr 2, s. 155-160Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The purpose of this study was to evaluate the clinical performance of glass ionomer cement (GIC) restorations comparing two minimally invasive methods in permanent teeth after 12 months. Fifty pregnant women (second trimester of pregnancy), mean age 22 ± 5.30 years, were treated by two previously trained operators. The treatment approaches tested were: chemomechanical method (CarisolvTM; MediTeam) and atraumatic restorative treatment (ART). A split-mouth study design was used in which the two treatments were randomly placed in 50 matched pairs of permanent teeth. The chemomechanical method (CM) was the test group and the ART was the control group. The treatments were performed in Public Health Centers. The tested restorative material was a high-strength GIC (Ketac Molar; 3M/ESPE). The restorations were placed according to the ART guidelines. Two calibrated independent examiners evaluated the restorations in accordance with ART criteria. The inter-examiner kappa was 0.97. Data were analyzed using 95% confidence interval on the binomial distribution and Fisher's exact test at 5% significance level. In a 12-month follow-up, 86% of the restorations were evaluated. In the test group (CM), 100% (CI=93.3-100%) of the restorations were considered successful. In the control group (ART) 97.6% (CI=87.4-99.9%) of the restorations were considered successful and 2.4% unsuccessful (marginal defect >0.5 mm). There was no statistically significant difference between the 12-mounth success rate for both groups (Fisher's exact test: P=0.49) and between the two operators (Fisher's exact test: P=1.00). Both minimally invasive methods, chemomechanical method and ART, showed a similar clinical performance after 12 months of follow up. Key words: Clinical trials. Restorations. Glass ionomer cements. Atraumatic Restorative Treatment. chemomechanical method. Carisolv.

  • 40.
    Jørgensen, Mette Rose
    et al.
    Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
    Keller, Mette Kirstine
    Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
    Kragelund, Camilla
    Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
    Hamberg, Kristina
    Malmö högskola, Odontologiska fakulteten (OD).
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Nielsen, Claus Henrik
    Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Institute for Inflammation Research, Department of Rheumatology and Spine Disease, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
    Twetman, Svante
    Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
    Lactobacillus reuteri supplements do not affect salivary IgA or cytokine levels in healthy subjects: A randomized, double-blind placebo-controlled, cross-over trial2016Ingår i: Acta Odontologica Scandinavica, ISSN 0001-6357, E-ISSN 1502-3850, Vol. 74, nr 5, s. 399-404Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objectives: To evaluate the effect of daily ingestion of probiotic lactobacilli on the levels of secretory IgA (sIgA) and selected cytokines in whole saliva of healthy young adults. Materials and methods: The study group consisted of 47 healthy adults (18-32 years) who volunteered for a randomized, double-blind, placebo-controlled, cross-over trial after informed consent. During intervention, the subjects ingested two lozenges per day containing two strains of the probiotic bacterium Lactobacillus reuteri (DSM 17938 and ATCC PTA 5289) or placebo lozenges. The intervention and wash-out periods were 3 weeks. Saliva samples were collected at baseline, immediately after each intervention period and 3 weeks post-intervention. ELISA was used to measure sIgA and luminex technology was used to measure the interleukins (IL)-1, IL-6, IL-8 and IL-10. For statistical analyses a mixed ANOVA model was employed to calculate changes in the salivary outcome variables Results: Forty-one subjects completed the study and reported a good compliance. No significant differences in the concentrations of salivary sIgA or cytokines were recorded between the L. reuteri and placebo interventions or between baseline and 3 weeks post-intervention levels. No side- or adverse effects were reported Conclusions: Supplementation with two strains of the probiotic L. reuteri did not affect sIgA or cytokine levels in whole saliva in healthy young adults. The results thereby indicate that daily oral supplementation with L. reuteri do not seem to modulate the salivary oral immune response in healthy young subjects

  • 41. Kacergius, Tomas
    et al.
    Timinskas, Arvydas
    Kalesinskas, Povilas
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Antisense Oligonucleotide in Fluoride Mouthwash Inhibits Mutans Streptococci Biofilm Formation2017Konferensbidrag (Övrigt vetenskapligt)
    Abstract [en]

    Objectives To test if a new biofilm-inhibiting antisense phosphorothioate oligodeoxyribonucleotide (PS-ODN) targeting simultaneously the selected homologous region of Streptococcus mutans glucosyltransferase (gtf) B, gtfC and Streptococcus sobrinus gtfI mRNAs is compatible with a sodium fluoride (NaF) mouthwash in suppressing streptococci biofilm formation in vitro. Methods Mixed cultures of S. mutans UA159 and S. sobrinus SL1 bacteria were grown anaerobically on vertical glass slides in 24-well cell culture plates containing Todd Hewitt broth with 1% sucrose and sterile-filtered human saliva (1:10) or 10% heat-inactivated horse serum under exposure to 10 µM of PS-ODN (5ʹ-GCAGACCATTGCTTAATCT-3ʹ) and 22.6 ppm of fluoride resulting from mouthwash (% w/v): 0.06% PS-ODN, 0.05% NaF, 0.1% saccharin-Na, 0.2% menthol. Untreated bacteria and bacteria exposed to mouthwash without PS-ODN, served as controls. After 24 h of incubation, glass slides were air-dried and further used for quantitative evaluation of biofilm applying optical profiler Sensofar PLµ 2300 and Gwyddion 2.27 software. Data obtained from two experiments (n=12, surface roughness; n=10, biofilm thickness) were analyzed using SPSS 23.0 program. Results The PS-ODN in combination with NaF mouthwash decreased surface roughness (parameter Rq) of the biofilm-covered glass slides by 62% and 75% versus untreated bacteria (p<0.05) in medium containing saliva and serum, respectively. This combination also reduced biofilm thickness by 88% and 78% versus untreated bacteria (p<0.05) in medium with saliva and serum, respectively. Mouthwash alone decreased roughness (parameter Rq) by 23% compared to untreated bacteria (p<0.05) growing in presence of saliva but not in serum-containing medium (p>0.05), whereas it reduced biofilm thickness by 38% and 22% versus untreated bacteria (p<0.05) in medium with saliva and serum, respectively. Conclusions The antisense PS-ODN is compatible with a NaF mouthwash and significantly inhibits mutans group streptococci biofilm formation on glass, and the combination might therefore be used as antibiofilm and/or anticaries agent in mouthwash formulations.

  • 42. Kalesinskas, Povilas
    et al.
    Kačergius, Tomas
    Ambrozaitis, Arvydas
    Pečiulienė, Vytautė
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Reducing dental plaque formation and caries development: A review of current methods and implications for novel pharmaceuticals2014Ingår i: Stomatologija, ISSN 1392-6470, Vol. 16, nr 2, s. 44-52Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Dental caries remains one of the most prevalent human diseases due to uncontrolled increase of dietary sucrose consumption in modern society. Sucrose is metabolized by Streptococcus mutans and Streptococcus sobrinus to acids causing tooth decay. These streptococci produce glucosyltransferases (Gtfs) for synthesis of sticky glucan polymers from sucrose, which is important for biofilm formation on teeth. In order to reduce dental biofilm build-up and oral diseases it causes, one preventive measure could be blocking of Gtf synthesis. Therefore, aim of this study was to test antisense phosphorothioate oligodeoxyribonucleotide (PS-ODN) targeting simultaneously S. mutans gtfB, gtfC and S. sobrinus gtfI mRNAs in order to inhibit biofilm formation in vitro. Materials and methods. Mixed culture of S. mutans and S. sobrinus bacteria were grown anaerobically on glass slides inserted vertically in 24-well cell culture plates containing Todd Hewitt broth with sucrose and sterile saliva under exposure to antisense or missense PS-ODNs at final concentration of 10 microM. Untreated bacteria served as controls. After 24 h of incubation, glass slides were removed, air-dried and further used for quantitative evaluation of streptococci biofilm applying optical profilometry technique. Results. It was found that antisense PS-ODN significantly reduced biofilm surface roughness and thickness of mixed S. mutans and S. sobrinus culture suppressing the biofilm development by 1.5-fold overall in comparison to untreated and missense PS-ODN-treated bacteria. Conclusions. Data demonstrate that antisense PS-ODN considerably attenuate streptococci-induced biofilm build-up on glass slides, and might therefore significantly inhibit dental biofilm formation through simultaneous inactivation of bacterial gtf mRNAs.

  • 43.
    Lager, Anders
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Svensäter, Gunnel
    Malmö högskola, Odontologiska fakulteten (OD).
    Microbiota in dentine caries cultivable on pH-selective agars2008Konferensbidrag (Refereegranskat)
    Abstract [en]

    Objective: To investigate the acid tolerant microflora at different levels in established dentine caries lesions using solid pH-selective media, as acid stress might be a major selective determinant in dentine caries ecosystems. Methods: Primary dentine caries lesions (vital teeth, no symptoms) in five patients were sampled aseptically with a rose-bur at three levels: superficially, in the centre and the bottom of the lesion, when it was considered clinically caries free using visual and tactile criteria. Samples were incubated on neutral (blood agar) and pH-selective (Todd-Hewitt agar buffered to pH 4.0, 4.5, 5.0, 5.5) agar. Numbers of colony-forming units (cfu) were determined and colonies were characterized morphologically and with enzymatic- and sugar fermentation tests. Results: The total numbers of bacteria recovered from the pH-neutral agars did not decrease significantly with lesion depth (median blood agar: 6.3×103 superficially; 2.2×103 bottom) whereas cfu recovery from low pH agars decreased with increasing agar acidity. The composition of the aciduric microflora varied both between subjects and between sample sites within the lesions. Gram-positive cocci were most abundant, but with lower pH and deeper sampling sites, the numbers of lactobacilli and other Gram-positive rods increased. Mutans streptococci were found at all sampling depths. S. anginosus, S. constellatus, S. crista, S. gordonii, S. intermedius and S. sanguis were found less frequently. Conclusions: The study clearly indicates that many different microorganisms can be recovered on pH 5.5 agars and thus survive in low pH environments. pH 5.5 is quite sufficient to moderately demineralize dentine, and aciduric microorganisms should thus have the potential to contribute to the dentine caries process. Approved by the ethical committee at Lund University. Funded by Faculty grants.

  • 44.
    Lager, Anders
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Thornqvist, E
    Svensäter, G
    Malmö högskola, Odontologiska fakulteten (OD).
    Lindberg, Birgitta
    Acid tolerant streptococci in dentine caries using pH-selective agars2006Konferensbidrag (Övrigt vetenskapligt)
    Abstract [en]

    Objectives: To investigate the acid tolerant microflora in dentine caries, with special respect to oral streptococci cultivable on pH-selective agar media, as acid stress might be a major selective force in dentine caries. Methods: Five patients with primary dentine caries lesions (vital teeth, no symptoms) participated in the study. Caries lesions were excavated aseptically under rubber-dam using rose-burs. Dentine sampling was performed using sterile rose-burs at 3 levels: superficially, in the centre and in the cavity floor. Samples were incubated on neutral (blood agar) and pH-selective agars (Todd-Hewitt agar with citrate-phosphate buffer; pH 4.5, 5.0 and 5.5). Numbers of colony-forming units (CFUs) were determined, characterized morphologically, isolated to blood agar and then identified (Gram-reaction, cell- and colony morphology). Each colony type was frozen in skim milk (158 isolates). Isolates described as streptococci were revived, re-incubated (65 isolates) and further characterized by enzymatic- and sugar fermentation tests. Results: The same bacterial counts were recovered from superficial, center and cavity floor, respectively. Each dentine sample exhibited a unique microflora. There was no significant difference in proportions of aciduric microorganisms in different levels in the lesion. Approximately 38% (superficial), 5% (centre) and 38% (cavity floor) of the total cultivable microbiota was able to grow at pH 5.5, a pH value critical for demineralisation of dentine. The acid-tolerant streptococcal isolates included mutans streptococci, S. anginosus, S. constellatus and a group of unidentified streptococci. Lactate consuming taxa were found in one case, but only at pH 5.5. Conclusion: There was no significant difference in numbers of microorganisms on different levels in the lesion. Composition of the dentine caries microflora differs from lesion to lesion. The dentine caries microflora consortia differ from lesion to lesion. A common property of these bacteria was acid tolerance. Approved by the ethical committee Lund University. Funded by Faculty grants.

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  • 45.
    Lager, Anders
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Thornqvist, Elisabeth
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Cultivatable bacteria in dentine after caries excavation using rose-bur or carisolv2003Ingår i: Caries Research, ISSN 0008-6568, E-ISSN 1421-976X, Vol. 37, nr 3, s. 206-211Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    To measure the amount of viable bacteria after excavation using conventional rose-bur or the chemo-mechanical Carisolv method, a total of 22 lesions were analyzed (one vital tooth per patient) in this open, controlled and randomized study. Two samples per lesion were taken under aseptic conditions using a rose-bur, one superficially in the caries lesion and one after completed excavation. In in vitro tests more material was collected from the hard caries free dentine as compared to the carious dentine. The samples were incubated on blood agar (aerobically and anaerobically), Rogosa (SL) agar and mitis salivarius (MS) agar. For blood agar (aerobic) both methods resulted in a significant decrease in CFU, for blood agar (anaerobic) and MS agar only the Carisolv method resulted in a significant decrease in CFU and for SL agar neither method resulted in a significant decrease in CFU. Comparing CFU before and after excavation, a considerable reduction of CFU was seen ranging from 10(1) to 10(4). Comparing the excavation methods, there were no significant differences, except in the case of blood agar (aerobic), which showed that Carisolv excavation was more effective in reducing CFU. This study indicated that bacterial sampling collected more material from hard dentine as compared from soft. Remaining bacteria after excavation were low in both groups. The Carisolv method seemed to remove bacteria at least up to and possibly beyond the extent of conventional drilling.

  • 46.
    Larsson, Kerstin
    et al.
    Malmö universitet, Odontologiska fakulteten (OD).
    Stime, Alexander
    Kungstandläkarna AB, Stockholm, Sweden.
    Hansen, Lisa
    Lycko Pers väg, Trelleborg, Sweden.
    Birkhed, Dowen
    Fersens väg, Malmö, Sweden.
    Ericson, Dan
    Malmö universitet, Odontologiska fakulteten (OD).
    Salivary fluoride concentration and retention after rinsing with 0.05 and 0.2% sodium fluoride (NaF) compared with a new high F rinse containing 0.32% NaF2020Ingår i: Acta Odontologica Scandinavica, ISSN 0001-6357, E-ISSN 1502-3850, Vol. 78, nr 8, s. 609-613Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    OBJECTIVE: To compare salivary fluoride (F) concentration and F retention after rinsing with a new 0.32% sodium fluoride (NaF) rinse and conventional 0.05 and 0.2% NaF rinses.

    METHODS: Seventeen subjects (aged 22-26 years), with normal salivary secretion rates, participated in a double blind, cross-over study. In three separate sessions with a minimum washout period of 48 h, they rinsed for 1 min with 10 ml of 0.05, 0.2 or 0.32% NaF mouthrinse. Unstimulated whole saliva was collected before (baseline: 0 min) and after 1, 3, 5, 10, 20, 30, 45 and 60 min. The F concentration was plotted against time, and the area under the curve (AUC) calculated. Salivary F concentration and F retention for the three mouthrinses were compared by a randomized block test, followed by Tukey's test and a paired 2-tailed test.

    RESULTS:  < .05).

    CONCLUSIONS: The higher salivary F concentration over time and the higher F retention after rinsing with an 0.32% NaF solution suggests a potential application in prevention of caries and dental erosion.

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  • 47.
    Leisnert, Leif
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Redmo Emanuelsson, Ing Mari
    Folktandvården Skåne, Malmö, Sweden.
    Papia, Evaggelia
    Malmö högskola, Odontologiska fakulteten (OD).
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Evaluation of an outreach education model over five years: Perception of dental students and their outreach clinical mentors2017Ingår i: European journal of dental education, ISSN 1396-5883, E-ISSN 1600-0579, Vol. 21, nr 2, s. 113-120Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    INTRODUCTION: The objective was to investigate changes in students' and clinical mentors' perceptions of a model for outreach education over a 5-year period, 2006-2010. MATERIAL AND METHOD: Two cohorts of last-year students of a dental problem-based curriculum and their clinical mentors in the Public Dental Service (PDS) were invited to respond to a questionnaire. In 2006, 85% of 54 students and 72% of their 54 mentors responded; 98% of 40 students and 88% of 41 of the mentors did so in 2010. Participants scored their level of agreement with different statements on a numeric rating scale and gave comments. RESULTS: Dental students and their clinical mentors reported that they shared a consistent and favourable perception of this outreach education model over 5 years. The students reported increased professional confidence and self-reliance. Clinical mentors expressed a transfer of knowledge to their clinics. Differences in scoring were seen between students and mentors for two statements in 2006 and two statements in 2010 (P < 0.05). CONCLUSIONS: The current model for outreach education received favourable and stable ratings over the 5-year period. This model resulted in that students perceived that they became self-reliant, which may facilitate their transition from being a student to becoming a professional. The current model supports exchange and professional development for students, faculty and outreach clinics. This leads us to look at outreach education as an opportunity to form a mutual learning community comprised of the outreach clinics and the dental school.

  • 48. Looström, Henning
    et al.
    Åkerman, Sigvard
    Malmö högskola, Odontologiska fakulteten (OD).
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Tobin, Gunnar
    Götrick, Bengt
    Malmö högskola, Odontologiska fakulteten (OD).
    Tramadol-induced oral dryness and pilocarpine treatment: Effects on total protein and IgA2011Ingår i: Archives of Oral Biology, ISSN 0003-9969, E-ISSN 1879-1506, Vol. 56, nr 4, s. 395-400Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Pilocarpine induces a profuse flow of saliva, and it may re-establish saliva production in cases of drug-induced oral dryness. The aim of the study (a sub-study to the previous trial investigating the pilocarpine fluid effects in individuals suffering from drug-induced dry mouth) was to search for saliva quality changes induced by the treatments. Sixty-five individuals were enrolled in a randomized, double-blind, placebo-controlled trial. The subjects received tramadol to induce oral dryness. Secretion rate was measured before and after tramadol, and then after pilocarpine, placebo, or no treatment. All saliva was analyzed for its protein and IgA content in the pilocarpine (n=15) and placebo groups (n=12). At baseline, the flow of saliva was 0.47±0.05ml/min, the protein output 0.17±0.2mg/min and the IgA output 0.022±0.002mg/min. After tramadol treatment (50mg 3×/day over two days), the flow was reduced by 64%, protein output by 52% and the IgA output by 38%. While placebo treatment did not affect any of the variables, the flow was 120%, the protein output 193% and the IgA output 83% of the baseline characteristics after pilocarpine treatment (5mg). Thus, the pilocarpine-induced increase in the flow rate in the state of tramadol-induced oral dryness results in saliva with a well preserved protein concentration but with a decrease in IgA concentration. However, compared to baseline, there was neither a decrease in output nor in concentration of IgA.

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  • 49.
    Lundin Wallengren, Marie Louise
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Hamberg, Kristina
    Malmö högskola, Odontologiska fakulteten (OD).
    Salivary IgA reactions to cell-surface antigens of oral streptococci.2004Ingår i: Oral Microbiology and Immunology, ISSN 0902-0055, E-ISSN 1399-302X, Vol. 19, nr 3, s. 188-195Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND: In the immunoblot technique, using whole bacteria cell extracts as antigens, both intra- and extracellular antigens are de-tected, which gives a large number of immunoglobulin A (IgA) reac-tions (immunoblot bands) when incubated with saliva. It is important to distinguish which immunoblot bands represent bacterial cell-surface antigens, since these antigens could be involved in adhesion mecha-nisms and be available for blocking in vivo. METHODS: Bacterial ex-tracts of Streptococcus mutans, Streptococcus sobrinus, Streptococcus parasanguis and the streptococcal antigen I/II were separated using SDS-PAGE. The antigens were detected with saliva in Western blot. Untreated saliva and saliva in which cell-surface reactive IgA had been absorbed with whole bacteria cells were analyzed. RESULTS: Ap-proximately half the number of the bands were absent for saliva ab-sorbed with homologous cells, compared to untreated saliva. The ab-sorption pattern was almost identical for S. mutans and S. sobrinus but not for S. parasanguis. Salivary IgA reactive against streptococcal antigen I/II was absorbed by S. mutans cells, to a lesser extent by S. sobrinus cells, and not at all by S. parasanguis cells. CONCLUSION: It is likely that the bands that were absent after absorption represented cell-surface antigens. For S. mutans and S. sobrinus, these bands were probably the streptococcal antigen I/II. Copyright Blackwell Munks-gaard, 2004.

  • 50. Lynch, Christopher D
    et al.
    Guillem, Sarah E
    Nagrani, Bharat
    Gilmour, Alan SM
    Ericson, Dan
    Malmö högskola, Odontologiska fakulteten (OD).
    Attitudes of some European dental undergraduate students to the placement of direct restorative materials in posterior teeth2010Ingår i: Journal of Oral Rehabilitation, E-ISSN 1365-2842, Vol. 37, nr 12, s. 916-926Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Summary The aim of this article was to report on the attitudes, opinions and confidences of final year dental students in three European schools towards the restoration of posterior teeth and in particular towards the use of amalgam and resin composite. One hundred and twenty-eight pre-piloted questionnaires were distributed to final year dental students in Cardiff, Dublin and Malmö. The questionnaire sought information relating to various opinions and attitudes towards the use of amalgam and resin composite in posterior teeth. Information was returned anonymously. Ninety-one completed questionnaires were returned (response rate = 71%; Cardiff: n = 40, Dublin: n = 24, Malmö: n = 27). Ninety-three per cent of Malmö students (n = 24), 67% of Dublin students (n = 16) and 60% of Cardiff students (n = 24) reported that they feel confident when placing posterior resin composites. One hundred per cent of Malmö students (n = 27), 75% of Cardiff students (n = 30) and 33% of Dublin students (n = 8) would prefer to have a resin composite rather than amalgam, placed in one of their own posterior teeth. Eighty-five per cent of Malmö students (n = 23), 30% of Cardiff students (n = 12) and 25% of Dublin students (n = 6) perceive amalgam as being harmful to the environment. For the restoration of a posterior tooth in a pregnant female, 44% of students (n = 40) would place a resin composite restoration, and 7% (n = 6) would place an amalgam restoration, while 32% (n = 29) would place a temporary restoration. Students at Malmö report that they place more posterior resin composites and have greater confidence at placing posterior resin composites than students at Cardiff or Dublin. There was confusion relating to the choice of restorative materials for pregnant females. Large variations in restorative strategies among graduates must be considered as dental professionals can practice in all countries within the European Union.

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