Malmö University Publications
Change search
Refine search result
1 - 2 of 2
CiteExportLink to result list
Permanent link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Rows per page
  • 5
  • 10
  • 20
  • 50
  • 100
  • 250
Sort
  • Standard (Relevance)
  • Author A-Ö
  • Author Ö-A
  • Title A-Ö
  • Title Ö-A
  • Publication type A-Ö
  • Publication type Ö-A
  • Issued (Oldest first)
  • Issued (Newest first)
  • Created (Oldest first)
  • Created (Newest first)
  • Last updated (Oldest first)
  • Last updated (Newest first)
  • Disputation date (earliest first)
  • Disputation date (latest first)
  • Standard (Relevance)
  • Author A-Ö
  • Author Ö-A
  • Title A-Ö
  • Title Ö-A
  • Publication type A-Ö
  • Publication type Ö-A
  • Issued (Oldest first)
  • Issued (Newest first)
  • Created (Oldest first)
  • Created (Newest first)
  • Last updated (Oldest first)
  • Last updated (Newest first)
  • Disputation date (earliest first)
  • Disputation date (latest first)
Select
The maximal number of hits you can export is 250. When you want to export more records please use the Create feeds function.
  • 1.
    Sohmen, Benedikt
    et al.
    Institute of Physical Chemistry University of Freiburg Albertstrasse 21 79104 Freiburg Germany.
    Beck, Christian
    Institute of Applied Physics University of Tübingen Auf der Morgenstelle 10 72076 Tübingen Germany;Science Division Institut Max von Laue ‐ Paul Langevin 71 avenue des Martyrs Grenoble 38042 France.
    Frank, Veronika
    Institute of Physical Chemistry University of Freiburg Albertstrasse 21 79104 Freiburg Germany.
    Seydel, Tilo
    Science Division Institut Max von Laue ‐ Paul Langevin 71 avenue des Martyrs Grenoble 38042 France.
    Hoffmann, Ingo
    Science Division Institut Max von Laue ‐ Paul Langevin 71 avenue des Martyrs Grenoble 38042 France.
    Hermann, Bianca
    Institute of Physical Chemistry University of Freiburg Albertstrasse 21 79104 Freiburg Germany.
    Nüesch, Mark
    Department of Biochemistry University of Zurich Winterthurerstrasse 190 CH‐8057 Zurich Switzerland.
    Grimaldo, Marco
    Science Division Institut Max von Laue ‐ Paul Langevin 71 avenue des Martyrs Grenoble 38042 France.
    Schreiber, Frank
    Institute of Applied Physics University of Tübingen Auf der Morgenstelle 10 72076 Tübingen Germany.
    Wolf, Steffen
    Biomolecular Dynamics, Institute of Physics University of Freiburg Hermann‐Herder‐Strasse 3 79104 Freiburg Germany.
    Roosen-Runge, Felix
    Malmö University, Faculty of Health and Society (HS), Department of Biomedical Science (BMV). Malmö University, Biofilms Research Center for Biointerfaces. Division of Physical Chemistry Lund University Naturvetarvägen 14 22100 Lund Sweden.
    Hugel, Thorsten
    Institute of Physical Chemistry University of Freiburg Albertstrasse 21 79104 Freiburg Germany;Signalling Research Centers BIOSS and CIBSS University of Freiburg Schänzlestrasse 18 79104 Freiburg Germany.
    The Onset of Molecule‐Spanning Dynamics in Heat Shock Protein Hsp902023In: Advanced Science, E-ISSN 2198-3844, Vol. 10, no 36Article in journal (Refereed)
    Abstract [en]

    Protein dynamics have been investigated on a wide range of time scales. Nano- and picosecond dynamics have been assigned to local fluctuations, while slower dynamics have been attributed to larger conformational changes. However, it is largely unknown how fast (local) fluctuations can lead to slow global (allosteric) changes. Here, fast molecule-spanning dynamics on the 100 to 200 ns time scale in the heat shock protein 90 (Hsp90) are shown. Global real-space movements are assigned to dynamic modes on this time scale, which is possible by a combination of single-molecule fluorescence, quasi-elastic neutron scattering and all-atom molecular dynamics (MD) simulations. The time scale of these dynamic modes depends on the conformational state of the Hsp90 dimer. In addition, the dynamic modes are affected to various degrees by Sba1, a co-chaperone of Hsp90, depending on the location within Hsp90, which is in very good agreement with MD simulations. Altogether, this data is best described by fast molecule-spanning dynamics, which precede larger conformational changes in Hsp90 and might be the molecular basis for allostery. This integrative approach provides comprehensive insights into molecule-spanning dynamics on the nanosecond time scale for a multi-domain protein.

    Download full text (pdf)
    fulltext
  • 2.
    Tidefelt, Mattias
    et al.
    Malmö University, Faculty of Technology and Society (TS), Department of Materials Science and Applied Mathematics (MTM).
    Löstrand, Julia
    Uppsala Univ, Div Mat Phys, Dept Phys & Astron, Box 530, SE-75121 Uppsala, Sweden..
    Goetz, Inga K.
    Uppsala Univ, Div Mat Phys, Dept Phys & Astron, Box 530, SE-75121 Uppsala, Sweden..
    Donzel-Gargand, Olivier
    Uppsala Univ, Div Solar Cell Technol, Dept Mat Sci & Engn, Angstrom Solar Ctr, S-75121 Uppsala, Sweden..
    Ericsson, Anders
    Lund Univ, Div Solid Mech, POB 118, SE-22100 Lund, Sweden..
    Han, Xiaoliang
    Leibniz Inst Solid State & Mat Res, Helmholtzstr 20, D-01069 Dresden, Germany..
    Joensson, Petra E.
    Uppsala Univ, Div Mat Phys, Dept Phys & Astron, Box 530, SE-75121 Uppsala, Sweden..
    Sahlberg, Martin
    Uppsala Univ, Dept Chem, Angstrom Lab, Box 538, SE-75121 Uppsala, Sweden..
    Kaban, Ivan
    Leibniz Inst Solid State & Mat Res, Helmholtzstr 20, D-01069 Dresden, Germany..
    Fisk, Martin
    Malmö University, Faculty of Technology and Society (TS), Department of Materials Science and Applied Mathematics (MTM). Lund Univ, Div Solid Mech, POB 118, SE-22100 Lund, Sweden..
    In Situ Mapping of Phase Evolutions in Rapidly Heated Zr-Based Bulk Metallic Glass with Oxygen Impurities2024In: Advanced Science, E-ISSN 2198-3844, Vol. 11, no 16Article in journal (Refereed)
    Abstract [en]

    Metallic glasses exhibit unique mechanical properties. For metallic glass composites (MGC), composed of dispersed nanocrystalline phases in an amorphous matrix, these properties can be enhanced or deteriorated depending on the volume fraction and size distribution of the crystalline phases. Understanding the evolution of crystalline phases during devitrification of bulk metallic glasses upon heating is key to realizing the production of these composites. Here, results are presented from a combination of in situ small- and wide-angle X-ray scattering (SAXS and WAXS) measurements during heating of Zr-based metallic glass samples at rates ranging from 102 to 104 Ks-1 with a time resolution of 4ms. By combining a detailed analysis of scattering experiments with numerical simulations, for the first time, it is shown how the amount of oxygen impurities in the samples influences the early stages of devitrification and changes the dominant nucleation mechanism from homogeneous to heterogeneous. During melting, the oxygen rich phase becomes the dominant crystalline phase whereas the main phases dissolve. The approach used in this study is well suited for investigation of rapid phase evolution during devitrification, which is important for the development of MGC. Oxygen impurities impact on phase-transformations during rapid heating of Zr-based metallic glass Zr59.3Cu28.8Al10.4Nb1.5 is thoroughly investigated using a multi-technique approach. During devitrification, the extracted phase evolutions reveal that the phase fraction hierarchy correlates with the oxygen impurity concentration. Numerical simulations with a heterogeneous nucleation mode capture the experimental observations. During melting, the oxygen-rich phase becomes the dominant phase. image

    Download full text (pdf)
    fulltext
1 - 2 of 2
CiteExportLink to result list
Permanent link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf