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Immediate loading of implants in the edentulous maxilla
Malmö högskola, Faculty of Odontology (OD).
2008 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

The overall aim of this thesis was to investigate different therapeutic strategies in treatment of the edentulous maxilla with dental implants and their importance for treatment outcome. The introduction of one-stage surgery, in place of two-stage surgery, was a paradigm shift in the area of implant treatment since submerged implant healing underneath the mucosa was considered a prerequisite for healing in the original concept. The advantages of a one-stage method are that a second surgery is unnecessary, costs are lower, and patients complain less about the surgical procedures. The development of implant treatment, regardless of whether it is performed in the mandible or the maxilla, strives to shorten the period from implant placement to implant loading. For the edentulous patient--due to esthetic, economical, or psychological reasons--shortening this time and thus avoiding a long period of wearing a transitional removable prosthesis is advantageous. Use of conventional one-stage surgery makes possible and is a prerequisite for immediate loading of implants. Successful treatment outcome has been demonstrated for immediate loading of implants in the mandible, but documentation of the method in the maxilla is still sparse. Two prospective clinical studies compared (i) one- and two-stage surgery and (ii) immediate and conventional loading in patients consecutively treated in the edentulous maxilla with implant-supported fixed prostheses. The first study found that the cumulative survival rate (CSR) after one-stage surgery performed according to a conventional protocol was consistent with two-stage protocol CSRs reported in previous studies. The second study evaluated an immediate loading protocol that provided patients with interim fixed prostheses within 24 hours after implant placement. A comparison of the studies found no significant difference in CSRs. But it was found that when a conventional protocol was used, transitional removable prostheses could traumatize the bone-implant interface during healing by adverse loading on the implants, which pierced the mucosa. Moreover, splinting the implants immediately after surgery with an interim fixed prosthesis might protect them from adverse loading. In a finite element analysis comparing uncoupled and splinted implants--imitations of the clinical situations in the two studies--splinted implants drastically reduced stresses in the bone tissue surrounding the implant, which might facilitate bone healing. Two factors considered important for a successful treatment outcome, especially when loading implants immediately, are (i) jawbone quality and (ii) primary implant stability at placement. In implant literature, bone quality is generally equivalent to bone density. Results of the third clinical study in this thesis indicate that use of computed tomography with calculations of bone mineral density can be a useful tool in bone tissue evaluation before implant placement. After 1 year of loading, changes in marginal bone level, compared to baseline, did not differ between implants that were stable and implants that were not stable at placement. The results of this thesis do not strengthen earlier recommendations that immediate and early loading is a treatment alternative that can be considered only in jaws with good bone quality. In conclusion, immediate loading with interim fixed prostheses in the edentulous maxilla is a viable treatment alternative. Splinting of implants seems to be important in immediate loading, especially when bone density is low.

Place, publisher, year, edition, pages
Malmö: Malmö högskola, 2008. , p. 75
Series
Swedish dental journal. Supplement, ISSN 0348-6672 ; 2008:196
National Category
Odontology
Identifiers
URN: urn:nbn:se:mau:diva-75737PubMedID: 18637314Scopus ID: 2-s2.0-47949090726ISBN: 9171042970 (print)OAI: oai:DiVA.org:mau-75737DiVA, id: diva2:1956228
Public defence
2008-05-23, Aula, Tandvårdshögskolan, Malmö, 09:15 (English)
Opponent
Note

Article IV in dissertation as manuscript

Available from: 2025-05-05 Created: 2025-05-05 Last updated: 2025-09-08Bibliographically approved
List of papers
1. Implant-supported Fixed Prostheses in the Edentulous Maxilla. A 2-year Clinical and Radiological Follow-up of Treatment with Non-submerged ITI Implants
Open this publication in new window or tab >>Implant-supported Fixed Prostheses in the Edentulous Maxilla. A 2-year Clinical and Radiological Follow-up of Treatment with Non-submerged ITI Implants
2004 (English)In: Clinical Oral Implants Research, ISSN 0905-7161, E-ISSN 1600-0501, Vol. 15, no 3, p. 351-359Article in journal (Other academic)
Abstract [en]

OBJECTIVES: To evaluate the survival rate of non-submerged solid-screw ITI dental implants with a rough (titanium plasma sprayed, TPS) surface in the edentulous maxilla after 1 and 2 years of loading. MATERIAL AND METHOD: Twentyfive patients (mean age 64 years) with edentulous upper jaws received five-seven implants and, after a mean healing time of 6.9 months, screw-retained implant-supported fixed prostheses. A total of 146 ITI solid screw TPS implants were inserted. The diameter of 56% of the implants was smaller (3.3 mm) than the standard (4.1 mm) and the diameter of the rest (44%) was standard. The bone quantity of the majority of the patients was low and the bone quality poor. Clinical parameters were registered at baseline and at two annual follow-ups. Radiological examinations and assessments were also made at these times. RESULTS: Mean marginal bone level at baseline was measured at a point 4.52 mm (range 1.45-7.70, SD 1.2) apical of the reference point. Mean bone loss from baseline to 1 year of loading was 0.24 mm (SD 0.9, P=0.002) and from 1 year to 2 years of loading 0.15 mm (SD 0.4, P<0.001). Five implants failed, four of which were early failures prior to loading. One implant failed shortly after bridge installation. The cumulative survival rate was 96.6% after 1 and 2 years. CONCLUSION: ITI TPS solid-screw implants in combination with fixed prostheses had successful survival rates and were found to be a viable treatment alternative in the edentulous maxilla.

National Category
Dentistry
Identifiers
urn:nbn:se:mau:diva-6672 (URN)10.1111/j.1600-0501.2004.01017.x (DOI)000221298600013 ()15142099 (PubMedID)2-s2.0-3042524205 (Scopus ID)2983 (Local ID)2983 (Archive number)2983 (OAI)
Available from: 2020-02-28 Created: 2020-02-28 Last updated: 2025-05-05Bibliographically approved
2. Immediately Loaded Implants Supporting Fixed Prostheses in the Edentulous Maxilla: A Preliminary Clinical and Radiologic Report
Open this publication in new window or tab >>Immediately Loaded Implants Supporting Fixed Prostheses in the Edentulous Maxilla: A Preliminary Clinical and Radiologic Report
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2005 (English)In: International Journal of Oral & Maxillofacial Implants, ISSN 0882-2786, E-ISSN 1942-4434, Vol. 20, no 3, p. 399-405Article in journal (Other academic) Published
Abstract [en]

PURPOSE: To evaluate the survival rate of immediately loaded ITI sand-blasted, large-grit, acid-etched (SLA) solid-screw dental implants in the edentulous maxilla after 8 months of loading. MATERIALS AND METHODS: Twenty-eight patients (mean age 63 years) with edentulous maxillae each received 6 implants and 1 implant-supported fixed provisional prosthesis within 24 hours after surgery. After a mean healing time of 15 weeks, the patient received a definitive, screw-retained, implant-supported fixed prosthesis. A total of 168 implants were placed. Clinical parameters were registered after 1 month of loading with the implant-supported fixed prostheses as well as 8 months after implant placement. Radiologic examinations and assessments were made at implant placement and after 8 months. RESULTS: The mean marginal bone level at implant placement was 1.6 mm (range 0 to 5.1; SD 1.1) apical of the reference point (the implant shoulder). The mean marginal bone level at the 8-month follow-up was 3.2 mm (range 0.4 to 5.9; SD 1.1) apical of the reference point. Three implants failed during the healing period. DISCUSSION: The improved results in the present study might be a result of the positive effect of splinting the implants immediately after placement. CON-CLUSION: ITI SLA solid-screw implants immediately loaded (ie, loaded within 24 hours of placement) and supporting fixed prostheses had successful survival rates after 8 months. The present results constitute a solid baseline for future follow-up studies.

National Category
Dentistry
Identifiers
urn:nbn:se:mau:diva-7174 (URN)000229786800007 ()15973951 (PubMedID)2-s2.0-21344461711 (Scopus ID)3022 (Local ID)3022 (Archive number)3022 (OAI)
Available from: 2020-02-28 Created: 2020-02-28 Last updated: 2025-05-05Bibliographically approved
3. Immediate loading of implants in the edentulous maxilla: use of an interim fixed prosthesis followed by a permanent fixed prosthesis: a 32-month prospective radiological and clinical study
Open this publication in new window or tab >>Immediate loading of implants in the edentulous maxilla: use of an interim fixed prosthesis followed by a permanent fixed prosthesis: a 32-month prospective radiological and clinical study
Show others...
2009 (English)In: Clinical Implant Dentistry and Related Research, ISSN 1523-0899, E-ISSN 1708-8208, Vol. 11, no 1, p. 1-10Article in journal (Refereed)
Abstract [en]

PURPOSE: The aim of this study was to prospectively evaluate the survival rate of splinted and immediately loaded Straumann sandblasted, large-grit, acid-etched, solid-screw dental implants in the edentulous maxilla after 32 months of loading. MATERIALS AND METHODS: Twenty-eight patients (mean age 63 years) with edentulous maxillae received 168 implants (six each) and an implant-supported fixed interim prosthesis within 24 hours after surgery. After a mean healing time of 15 weeks, the patients received permanent screw-retained prostheses. Clinical and radiological examinations were made at implant placement and after 8, 20, and 32 months of loading. All permanent prostheses were removed at the 32-month follow-up; implant stability was checked with a torque device, and the implant stability quotient was determined with resonance frequency analysis. RESULTS: Mean marginal bone loss from baseline to 8 months after loading was 1.6 mm (SD 1.16; p = .094), from 8 to 20 months 0.41 mm (SD 0.63; p = .094), and from 20 to 32 months 0.08 mm (SD 0.49; p = .039). The 32-month cumulative survival rate was 98.2%. CONCLUSIONS: The 32-month survival of solid-screw implants - immediately loaded within 24 hours after placement - was similar to survival rates reported for solid-screw implants with conventional loading. Immediate loading and splinting of implants in the edentulous maxilla is a viable treatment alternative.

National Category
Dentistry
Identifiers
urn:nbn:se:mau:diva-6553 (URN)10.1111/j.1708-8208.2008.00094.x (DOI)000263243500001 ()18384401 (PubMedID)2-s2.0-60049086670 (Scopus ID)9445 (Local ID)9445 (Archive number)9445 (OAI)
Available from: 2020-02-28 Created: 2020-02-28 Last updated: 2025-05-05Bibliographically approved
4. Bone density at implant sites and its relationship to assessment of bone quality and treatment outcome
Open this publication in new window or tab >>Bone density at implant sites and its relationship to assessment of bone quality and treatment outcome
Show others...
2010 (English)In: International Journal of Oral & Maxillofacial Implants, ISSN 0882-2786, E-ISSN 1942-4434, Vol. 25, no 2, p. 321-328Article in journal (Refereed) Published
Abstract [en]

PURPOSE: To investigate the relationship between bone mineral density (BMD) before implant placement, implant stability measures at implant placement, and marginal bone loss of immediately loaded implants after 1 year in situ. MATERIALS AND METHODS: Consecutively recruited patients received Straumann SLActive implants loaded with fixed provisional prostheses within 24 hours. BMD was measured from computed tomographic images before implant placement. Alveolar bone quality was assessed during surgery. Implant stability-both rotational and as measured with resonance frequency analysis-and marginal bone height were assessed at implant placement and after 1 year. The Pearson correlation coefficient was used to calculate correlations, and significance was considered when P < .05. RESULTS: Twenty-one patients received 137 implants (87 in maxillae and 50 in mandibles). BMD was significantly correlated with bone quality classification in both arches (P < .001). Mean BMD was also significantly correlated with stability values (P < .001). Mean marginal bone loss at implant surfaces differed, but not significantly, at the 1-year follow-up, regardless of BMD values (P = .086) and measured stability (rotational stability P = .34, resonance frequency analysis P = .43) at implant placement. CONCLUSION: Within the limits of this study, it can be concluded that computed tomographic examination can be used as a preoperative method to assess jawbone density before implant placement, since density values correlate with prevailing methods of measuring implant stability. However, in the short time perspective of 1 year, there were no differences in survival rates or changes in marginal bone level between implants placed in bone tissue of different density.

National Category
Radiology, Nuclear Medicine and Medical Imaging
Identifiers
urn:nbn:se:mau:diva-6141 (URN)000276975600012 ()20369091 (PubMedID)2-s2.0-77953271736 (Scopus ID)11284 (Local ID)11284 (Archive number)11284 (OAI)
Available from: 2020-02-28 Created: 2020-02-28 Last updated: 2025-05-05Bibliographically approved
5. A Finite Element Analysis of Stress Distribution in Bone Tissue Surrounding Uncoupled or Splinted Dental Implants
Open this publication in new window or tab >>A Finite Element Analysis of Stress Distribution in Bone Tissue Surrounding Uncoupled or Splinted Dental Implants
Show others...
2008 (English)In: Clinical Implant Dentistry and Related Research, ISSN 1523-0899, E-ISSN 1708-8208, Vol. 10, no 1, p. 40-46Article in journal (Refereed) Published
Abstract [en]

Background: Several studies on one‐stage surgery in the treatment of the edentulous maxilla with implant‐supported fixed prostheses have reported problems with removable provisional prostheses, which can load the implants in an uncontrollable manner during healing, and jeopardize healing. Immediate splinting of the implants with a fixed provisional prosthesis has been proposed to protect the bone‐implant interface.

Purpose: This study used the finite element method (FEM) to simulate stresses induced in bone tissue surrounding uncoupled and splinted implants in the maxilla because of bite force loading, and to determine whether the differences in these stress levels are related to differences in observed bone losses associated with the two healing methods.

Materials and Methods: Stress levels in the maxilla were studied using the FEM program TRINITAS (Institute of Technology, Linköping University, Linköping, Sweden) in which all phases – preprocessing/modeling, equation solving, and postprocessing/evaluation – were simulated.

Results: Stress levels in bone tissue surrounding splinted implants were markedly lower than stress levels surrounding uncoupled implants by a factor of nearly 9.

Conclusion: From a mechanical viewpoint, FEM simulation supports the hypothesis that splinting reduces damage evolution in bone tissue, which agrees with clinical observations.

Place, publisher, year, edition, pages
Blackwell Publishing, 2008
National Category
Odontology
Identifiers
urn:nbn:se:mau:diva-75739 (URN)10.1111/j.1708-8208.2007.00059.x (DOI)000252806800005 ()18254739 (PubMedID)2-s2.0-38849142690 (Scopus ID)
Available from: 2025-05-05 Created: 2025-05-05 Last updated: 2025-08-20Bibliographically approved

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