Throughout the development process within organizations, various complications can appear that can reduce the quality of a software or contribute to immense costs to organizations. This is especially true for organizations that operate in fields such as the health industry where stern rules and requirements are often a fact. This paper explores challenges that can arise during the development process of health applications as well as what effects these can have on the applications and organizations. The paper then examines how these difficulties can be prevented or mitigated. The intention is that this thesis should help organizations and developers to be able to go through a development process effectively without being overwhelmed by difficulties that can arise during the development process of health applications.