Although satellite-based sensors have made vegetation data series available for several decades, the detection of vegetation trend and change is not yet straightforward. This is partly due to the scarcity of available change detection algorithms suitable for identifying and characterizing both abrupt and non-abrupt changes, without sacrificing accuracy or computational speed. We propose a user-friendly program for analysing vegetation time series, with two main application domains: generalising vegetation trends to main features, and characterizing vegetation trend changes. This program, Detecting Breakpoints and Estimating Segments in Trend (DBEST) uses a novel segmentation algorithm which simplifies the trend into linear segments using one of three userdefined parameters: a generalisation-threshold parameter δ, themlargest changes, or a threshold β for the magnitude of changes of interest for detection. The outputs of DBEST are the simplified trend, the change type (abrupt or non-abrupt), and estimates for the characteristics (time and magnitude) of the change. DBEST was tested and evaluated using simulated Normalized Difference Vegetation Index (NDVI) data at two sites, which included different types of changes. Evaluation results demonstrate that DBEST quickly and robustly detects both abrupt and non-abrupt changes, and accurately estimates change time and magnitude. DBEST was also tested using data from the Global Inventory Modeling and Mapping Studies (GIMMS) NDVI image time series for Iraq for the period 1982–2006, and was able to detect and quantify major change over the area. This showed that DBEST is able to detect and characterize changes over large areas. We conclude that DBEST is a fast, accurate and flexible tool for trend detection, and is applicable to global change studies using time series of remotely sensed data sets.