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Zirconium dioxide based dental restorations: studies on clinical survival and fracture behaviour
Malmö högskola, Faculty of Odontology (OD).ORCID iD: 0000-0002-3912-0830
2011 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [sv]

POPULÄRVETENSKAPLIG SAMMAN-FATTNINGAtt förlora tänder påverkar en människas utseende och funktioner såsom tal och tuggning. Det finns därmed ett behov att rehabilitera och ersätta förlorade tänder för att upprätthålla en god livskvalitet. För många patienter är en fastsittande konstruktion första-handsval, och en vanlig ersättning är en bro i metallunderstödd ke-ramik som fästs till kvarvarande egna tänder eller implantat. Me-tall-baserade rekonstruktioner innebär emellertid en viss risk för allergisk reaktion och det finns därmed indikation för att söka efter alternativa material.Keramer karaktäriseras av starka kemiska bindningar som gör dem obenägna att reagera med sin omgivning och därmed mycket vävnadsvänliga. De har även andra tilltalande materialegenskaper och erbjuder goda estetiska möjligheter och har använts fram-gångsrikt inom tandvården under lång tid, framförallt för små konstruktioner i framtandsområdet. Då keramer är känsliga för dragkrafter förekommer emellertid spröda frakturer, framförallt i övergången mellan led, den s.k. connectorn, i brokonstruktioner.Under senare år har en typ av keramer, baserade på zirkonium-dioxid, utvecklats. Yttria-stabiliserad tetragonal zirkoniumdioxid polykristaller, Y-TZP, har en unik förmåga att genom fasomvand-ling från en kristallstruktur till en annan, m.h.a efterföljande vo-lymsökning, kunna sluta en påbörjad spricka och hindra denna från att tillväxa. Detta material har potential att framgångsrikt kunna användas även för större brokonstruktioner och i kind-tandsområden. Det finns emellertid otillräcklig klinisk uppföljning av dentala zirkoniumdioxid-baserade konstruktioner, framförallt över längre tid, och information om helkeramiska broar på implan-tat saknas helt.Det övergripande målet med detta avhandlingsprojekt var att ut-värdera hur zirkoniumdioxid-baserade konstruktioner bör designas för ökad hållfasthet samt att utvärdera klinisk överlevnad av im-plantat-stödda zirkoniumdioxid-baserade konstruktioner.I delarbete I jämfördes implantat-stödda helkeramiska broar i två olika keramiska material; ett aluminiumoxidmaterial förstärkt med zirkoniumdioxid (grupp 1) och ett tät-sintrat Y-TZP material (grupp 2). Arton patienter randomiserades till endera av de två grupperna. Vid uppföljning efter ett år var alla broar i funktion, inga totalfrakturer noterades, men frakturer förekom i ytporslinet. Dessa förekom signifikant oftare i grupp 2 där 54% av broarna uppvisade yt-frakturer jämfört med 8% av broarna i grupp 1. Delarbete IV är en 5-års uppföljning av samma patientgrupper och resultaten visade fortsatt inga totalfrakturer men ökad före-komst av ytporslinsfrakturer; 69% (grupp 2) och 17% (grupp 1).Delarbete II utvärderade brotthållfastheten för partiella Y-TZP-baserade broskelett med olika dimension på connectorn; 2.0, 2.5, 3.0, 3.5 och 4.0 mm. Resultaten visade signifikant ökad brotthåll-fasthet för varje ökning i connector-dimension och rekommenda-tioner för dimensionering av connectorer föreslogs.Delarbete III utvärderade implantat-stödda Y-TZP-baserade 9-10 leds-broar i tandlösa underkäkar. Vid treårs-uppföljningen var alla broar i funktion, inga totalfrakturer konstaterades, men där-emot frakturer i ytporslinet. Dessa noterades hos nio av de tio pati-enterna, på 34% av ytorna.Delarbete V utvärderade brotthållfastheten hos kronor med oli-ka typer av Y-TZP kärnmaterial, olika design på kärnan samt olika ytporslin. Kronorna cementerades på tandliknande understöd, för-utom en grupp som cementerades på en implantat-liknande modell. Resultaten visade signifikant högre brotthållfasthet samt skillnader i frakturmösnter för kronor med en anatomiskt utformad kärna jämfört med kronor med en enkel jämntjock kärna. Kronor stödda av en implantat-liknande modell uppvisade signifikant högre brotthållfasthet. Typ av kärnmaterial eller ytporslin påverkade inte brotthållfastheten.

Abstract [en]

ABSTRACTThe loss of teeth can affect a person’s appearance and functions such as eating and speaking. There is thus a need for prosthetic re-habilitation to improve quality of life. For many patients, a fixed dental restoration is preferred, and a common restoration is a por-celain-fused-to-metal bridge retained by teeth or implants. Metal-based restorations can potentially cause adverse reactions though, and this is indication for the search for alternative materials. All-ceramic materials are characterized by strong atomic bonds that make them reluctant to react with the environment, and thus unlikely to cause adverse reactions. All-ceramic materials have other attractive material properties and excellent aesthetic proper-ties and have been successfully used in dentistry, mostly for smaller anterior restorations. Ceramics do not withstand tensile forces as well as metals though, and are susceptible to brittle fractures. The connector area is especially prone to fracture.During later years, a new type of ceramic material, based on zir-conium dioxide, has been developed. Yttria-stabilized tetragonal zirconia polycrystals, Y-TZP, has a unique ability to resist crack propagation by being able to transform from one crystalline phase to another, and the resultant volume increase stops the crack and inhibits it from propagating. This material has the potential to be used for larger restorations and in the molar area. Not enough in-formation, however, is available on clinical follow-up of zirconia-based restorations, especially long-term, and information on all-ceramic restorations supported by implants is lacking.The over-all aim of this thesis was to evaluate how to design zir-conia-based restorations to achieve increased fracture resistance and evaluate the clinical performance of implant-supported zirco-nia-based restorations.In paper I implant-supported all-ceramic fixed partial dentures of two different ceramic materials were compared; a zirconia-toughened alumina material (group 1) and a densely sintered Y-TZP material (group 2). Eighteen patients were randomly divided between the two groups. At the one-year follow-up, all restorations were in function and no complete fractures were noted. Fractures of the veneering material were noted, however. There was a signifi-cant difference between the two materials; 54% of the restorations in group 2 showed veneer fractures compared to 8% of the restora-tions in group 1. Paper IV is a five-year follow-up of the same patient groups. All restorations were still in function without complete fractures, but an increase in veneer fractures was noted; 69% of the restorations in group 2 showed veneer fractures compared to 17% in group 1.In paper II the fracture strength was evaluated for 4-unit Y-TZP fixed dental prostheses frameworks with different connector di-mensions; 2.0, 2.5, 3.0, 3.5 and 4.0 mm. The results showed a sig-nificant increase in load at fracture for each increase in connector diameter and recommendations for clinically relevant connector dimensions were suggested. In paper III implant-supported Y-TZP fixed full-arch mandibular dentures were evaluated. At the three-year follow-up all restora-tions were in function and no complete fractures were noted. Frac-tures of the veneering material were however noted in nine of the ten patients, at 34% of the units. In paper V the fracture strength of crowns with different types of Y-TZP core materials and different core design and veneering ma-terials was evaluated. The crowns were cemented onto tooth-like abutments, except for one group cemented onto implant-like tita-nium abutments. The results showed significantly higher loads at fracture and different fracture mode for crowns with anatomically shaped cores compared to simple cores with even thickness. Crowns supported by implant-like titanium abutments showed sig-nificantly higher loads at fracture than did those supported by tooth-like abutments. Type of core-material and veneering material did not influence the results.

Place, publisher, year, edition, pages
Malmö University, Faculty of Odontology, Departments of Prosthetic Dentistry and Materials Science and Technology , 2011. , p. 84
Series
Swedish Dental Journal : Supplement, ISSN 0348-6672 ; 213
Keywords [en]
Zirconium dioxide, Y-TZP, Dental restorations
National Category
Dentistry
Identifiers
URN: urn:nbn:se:mau:diva-7737PubMedID: 21919311Scopus ID: 2-s2.0-80053302434Local ID: 11769ISBN: 978-91-7104-383-2 (print)OAI: oai:DiVA.org:mau-7737DiVA, id: diva2:1404678
Available from: 2020-02-28 Created: 2020-02-28 Last updated: 2024-12-02Bibliographically approved
List of papers
1. All-ceramic two- to five-unit implant-supported reconstructions: A randomized, prospective clinical trial
Open this publication in new window or tab >>All-ceramic two- to five-unit implant-supported reconstructions: A randomized, prospective clinical trial
2006 (English)In: Swedish Dental Journal, ISSN 0347-9994, Vol. 30, no 2, p. 45-53Article in journal (Refereed) Published
Abstract [sv]

Syftet med denna studie var att kliniskt utvärdera helkeramiska två- till femleds rekonstruktioner på implantat, samt att jämföra två olika keramiska system, Denzir® (DZ) och In-Ceram Zirconia® (InZ). Arton patienter behandlades med totalt 25 två- till femleds rekonstruktioner på implantat. Nio patienter fick rekonstruktioner utförda i DZ och nio patienter fick rekonstruktioner utförda i InZ. Rekonstruktionerna cementerades med zinkfosfatcement på preparerbara titandistanser. Rekonstruktionerna utvärderades efter 6- och 12 månader. Vid uppföljning efter 12 månader var alla 25 rekonstruktioner i funktion, inga hade frakturerat. Ytliga kohesiva, sk. chip-off, frakturer noterades däremot hos 6 av 18 patienter (8 av 25 rekonstruktioner). Nio led i DZ-gruppen (7 av 13 rekonstruktioner) och ett led i InZ-gruppen (1 av 12 rekonstruktioner) uppvisade chip-off frakturer. Skillnaden mellan de båda grupperna var statisktiskt signifikant (p< 0.01). Kantanslutningen bedömdes som utmärkt vid 34 stöd (56%) och acceptabel vid 27 stöd (44%). Resultat från denna 12 månaders uppföljning indikerar att helkeramiska två- till femleds rekonstruktioner på implantat kan övervägas som behandlingsalternativ. Vid jämförelse mellan de båda keramiska systemen är slutsatsen att DZ-systemet uppvisar oacceptabelt många frakturer i ytporslinet och därför inte kan rekommenderas för den typ av behandling som utvärderats här. Fortsatta studier och långtidsuppföljningar är nödvändiga innan ovan nämda material och teknik kan rekommenderas för allmänt bruk.

Abstract [en]

The purpose of this study was to evaluate the clinical performance of two to five-unit implant-supported all-ceramic reconstructions and to compare the results of two different all-ceramic systems, Denzir (DZ) and In-Ceram Zirconia (InZ). Eighteen patients were treated with a total of 25 two- to five-unit implant-supported reconstructions. Nine patients were given reconstructions of the DZ system and the other nine reconstructions of the InZ system.The reconstructions were cemented with zinc phosphate cement onto preparable titanium abutments and were evaluated after 6 and 12 months. At the 12-month follow-up, all reconstructions were in function; none had fractured. Superficial cohesive (chip-off) fractures were, however, observed in 6 of the 18 patients (8 of 25 reconstructions). Nine units in the DZ group (in 7 of 13 reconstructions) and one in the InZ group (1 of 12 reconstructions) had chip-off fractures. The difference between the two groups regarding frequency of chip-off fractures was statistically significant (P < 0.01). Marginal integrity was rated excellent at 34 abutments (56%) and acceptable at 27 (44%). Results from this 12-month trial suggest that all-ceramic implant-supported fixed partial dentures of two- to five-units may be considered a treatment alternative. When comparing the two ceramic systems under study, however, this study concludes that the DZ system exhibits an unacceptable amount of veneering porcelain fractures and thus cannot be recommended for the type of treatment evaluated in this trial. Further studies and long-term follow-ups must be performed before the materials and technique can be recommended for general use.

Place, publisher, year, edition, pages
Swedish Dental Association, 2006
National Category
Dentistry
Identifiers
urn:nbn:se:mau:diva-15932 (URN)000239028300001 ()16878679 (PubMedID)2-s2.0-33745810915 (Scopus ID)3519 (Local ID)3519 (Archive number)3519 (OAI)
Available from: 2020-03-30 Created: 2020-03-30 Last updated: 2025-05-07Bibliographically approved
2. Fracture strength of four-unit Y-TZP FPD cores designed with varying connector diameter. An in-vitro study.
Open this publication in new window or tab >>Fracture strength of four-unit Y-TZP FPD cores designed with varying connector diameter. An in-vitro study.
Show others...
2007 (English)In: Journal of Oral Rehabilitation, E-ISSN 1365-2842, Vol. 34, no 9, p. 702-709Article in journal (Refereed)
Abstract [en]

Reported clinical success rates of all-ceramic fixed partial dentures (FPDs) made of high-strength oxide ceramics range between 82.5% and 100%. The main cause of all-ceramic FPD failure is fracture in the connector area. There is, however, no consensus on what connector dimensions are adequate. The aim of this in-vitro study was, therefore, to compare the fracture strength of four-unit Y-TZP FPD cores designed with different connector diameters. A total of 40 four-unit FPD cores supported by end abutments and having two pontics were manufactured in Procera Zirconia. Five groups of FPD cores with connector dimensions of 2.0, 2.5, 3.0, 3.5 and 4.0 mm were produced. All FPD cores underwent a firing programme according to the manufacturer's recommendations for the veneering porcelain, a cyclic preload, thermocycling and finally, load until fracture. Fracture strength was significantly higher for each increase in connector diameter except for the 2.0-mm and 2.5-mm diameters where all fractures occurred during preload. All FPD cores fractured in the connector area. Within the limitations of this in-vitro study, a minimum diameter of 4.0 mm is recommended for all-ceramic zirconia-based FPDs with long spans or replacing molars. Clinical studies are, however, needed to determine adequate connector dimensions.

National Category
Dentistry
Identifiers
urn:nbn:se:mau:diva-15880 (URN)10.1111/j.1365-2842.2007.01770.x (DOI)000249181000009 ()17716270 (PubMedID)2-s2.0-34548107352 (Scopus ID)5463 (Local ID)5463 (Archive number)5463 (OAI)
Available from: 2020-03-30 Created: 2020-03-30 Last updated: 2024-02-05Bibliographically approved
3. A prospective study of implant-supported full-arch yttria-stabilized tetragonal zirconia polycrystal mandibular fixed dental prostheses: three-year results
Open this publication in new window or tab >>A prospective study of implant-supported full-arch yttria-stabilized tetragonal zirconia polycrystal mandibular fixed dental prostheses: three-year results
2010 (English)In: International Journal of Prosthodontics, ISSN 0893-2174, E-ISSN 1139-9791, Vol. 23, no 4, p. 364-369Article in journal (Refereed) Published
Abstract [en]

PURPOSE: The development of high-strength oxide ceramic materials has led to increased interest in all-ceramic fixed dental prostheses (FDPs). Success rates reported in clinical studies for all-ceramic FDPs based on high-strength oxide ceramic materials reportedly approach those of porcelain-fused-to-metal FDPs. These reconstructions, however, are still of limited size and have mainly concerned FDPs supported by natural teeth. The purpose of this study was to evaluate the clinical performance of multiunit all-ceramic FDPs supported by dental implants. MATERIALS AND METHODS: Ten patients received mandibular yttria-stabilized tetragonal zirconia polycrystal (Y-TZP) FDPs manufactured according to the Cercon technique and supported by four Astra Tech implants. Nine patients received 10-unit FDPs and one patient received a 9-unit FDP. The FDPs were cemented with Panavia F 2.0 onto individually prepared titanium abutments. The FDPs were evaluated at baseline and after 12, 24, and 36 months. RESULTS: At the 3-year follow-up, all FDPs were in use, and all patients were fully satisfied with their treatment. None of the reconstructions had fractured. Superficial chip-off fractures of the veneering porcelain were, however, observed in nine patients (34 of 99 units, 34%). CONCLUSION: Results from this 3-year study suggest that implant-supported full-arch Y-TZP FDPs manufactured according to the Cercon technique should be viewed as a treatment alternative cautiously. A better understanding of the factors resulting in chip-off fractures is needed, together with longer follow-up studies involving larger numbers of patients, before the material and technique can be recommended for general use.

Place, publisher, year, edition, pages
Quintessence, 2010
National Category
Dentistry
Identifiers
urn:nbn:se:mau:diva-15292 (URN)000280182500014 ()20617228 (PubMedID)2-s2.0-77957270939 (Scopus ID)11232 (Local ID)11232 (Archive number)11232 (OAI)
Available from: 2020-03-30 Created: 2020-03-30 Last updated: 2024-09-17Bibliographically approved
4. Five-year follow-up of implant-supported Y-TZP and ZTA fixed dental prostheses. A randomized, prospective clinical trial comparing two different material systems
Open this publication in new window or tab >>Five-year follow-up of implant-supported Y-TZP and ZTA fixed dental prostheses. A randomized, prospective clinical trial comparing two different material systems
2010 (English)In: International Journal of Prosthodontics, ISSN 0893-2174, E-ISSN 1139-9791, Vol. 23, no 6, p. 555-561Article in journal (Refereed) Published
Abstract [en]

PURPOSE: The aim of this study was to evaluate the clinical performance of two- to five-unit implant-supported all-ceramic restorations and to compare the results of two different all-ceramic systems, Denzir (DZ) and In-Ceram Zirconia (InZ). MATERIALS AND METHODS: Eighteen patients were treated with a total of 25 two- to five-unit implant-supported fixed dental prostheses. Nine patients were given DZ system restorations and 9 were given InZ system restorations. The restorations were cemented with zinc phosphate cement onto customized titanium abutments and were evaluated after 1, 3, and 5 years. RESULTS: At the 5-year follow-up, all restorations were in function; none had fractured. However, superficial cohesive (chip-off) fractures were observed in 9 of 18 patients (11 of 25 restorations). Sixteen units in the DZ group (9 of 13 restorations) and 3 in the InZ group (2 of 12 restorations) had chip-off fractures. The difference between the two groups regarding frequency of chip-off fractures was statistically significant (P < .05 at the FDP level and P < .001 at the unit level). CONCLUSION: The results suggest that all-ceramic implant-supported fixed dental prostheses of two to five units may be considered a treatment alternative. The DZ system, however, exhibited an unacceptable amount of veneering porcelain fractures and thus cannot be recommended for the type of treatment evaluated in this trial. Poor compatibility or problems with the bond mechanisms between the veneer and framework could not explain the chip-off fractures. Stress distribution, as well as other factors concerning the veneering porcelain, need to be evaluated further.

Place, publisher, year, edition, pages
Quintessence, 2010
National Category
Dentistry
Identifiers
urn:nbn:se:mau:diva-5881 (URN)000284987200013 ()21209993 (PubMedID)2-s2.0-79952260010 (Scopus ID)11499 (Local ID)11499 (Archive number)11499 (OAI)
Available from: 2020-02-28 Created: 2020-02-28 Last updated: 2024-06-11Bibliographically approved
5. Fracture strength of yttria-stabilized tetragonal zirconia polycrystals crowns with different design: an in-vitro study
Open this publication in new window or tab >>Fracture strength of yttria-stabilized tetragonal zirconia polycrystals crowns with different design: an in-vitro study
2012 (English)In: Clinical Oral Implants Research, ISSN 0905-7161, E-ISSN 1600-0501, Vol. 27, no 7, p. 820-826Article in journal (Refereed)
Abstract [en]

Abstract Objectives: The aim of this study was to evaluate the effect of different types and design of zirconia frameworks as well as the effect of different veneering ceramics on the fracture strength of crowns. The importance of different abutment materials was also evaluated. Materials and methods: Eighty cores, 40 in a fully-sintered zirconia material and 40 in a pre-sintered zirconia material were made. Twenty cores of each material were made with a core of even thickness shape (ES) and 20 were made with a core with anatomical shape (AS). The cores were divided into subgroups and veneered with one of two different veneering ceramics: a porcelain and a glass-ceramic material. In total eight groups of 10 crowns were made. They were all cemented onto abutments made of resin. One extra group of 10 AS, pre-sintered zirconia cores veneered with glass-ceramic were made and cemented onto titanium abutments. All crowns underwent thermocycling and mechanical pre-load and were finally loaded until fracture. Results: AS crowns withstood significantly higher loads than ES crowns (P-value <0.001), and crowns with titanium abutments withstood significantly higher loads than crowns supported by abutments made of inlay pattern resin (P-value <0.001). Three types of fracture were noted: minor and major fracture of the veneering ceramic, and complete fracture through core and veneer. ES crowns showed significantly more major fractures of the veneering ceramic than AS crowns. Conclusions: This in vitro study indicates that the design of the core, as well as the abutment support, significantly influences fracture load and fracture mode of yttria-stabilized tetragonal zirconia polycrystals crowns.

Place, publisher, year, edition, pages
Blackwell Munksgaard, 2012
Keywords
Y-TZP, zirconia, crown, design
National Category
Dentistry
Identifiers
urn:nbn:se:mau:diva-7022 (URN)10.1111/j.1600-0501.2011.02224.x (DOI)000304992500007 ()21635559 (PubMedID)2-s2.0-84862173910 (Scopus ID)13193 (Local ID)13193 (Archive number)13193 (OAI)
Available from: 2020-02-28 Created: 2020-02-28 Last updated: 2025-10-09Bibliographically approved

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