The purpose of this paper is to open up a discussion about the roles and responsibilities of universities in society. Design/methodology/approach – The vision of the Regional Centre of Expertise (RCE) Skane a leading example on how to develop new knowledge about education for sustainable development (ESD) at all levels. The paper poses the question "Why do universities involve in this process?". Lund University as the old, traditional university and the ten-year old university of Malmö on the other hand was formed on the bases of a vision about a university for all people. Findings – The paper finds that two universities have been active in creating RCE Skane, together with three political organizations. The vision has developed to include issues like capacity for cross-boundary action, knowledge-sharing and civic education, all important parts in learning for a sustainable future. Practical implications – The paper discusses the processes at these universities that led up to working together in RCE Skåne and the importance of having the Act on Higher Education in 2006 about responsibility for education for sustainability at all universities. Originality/value – In forming RCEs all over the world it is important to learn from each other and universities play an important role in these actions.