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On failures and complications of tooth-supported fixed prostheses
Malmö University, Faculty of Odontology (OD). Umm Al-Qura University, Saudi Arabia.ORCID iD: 0000-0002-4510-5071
2023 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Loss of tooth structure or loss of the tooth may affect masticatory function, phonetics, a person´s appearance, and might ultimately impair quality of life. Fixed prosthetic rehabilitation in the form of either fixed dental prosthesis (FDP)or single crown (SC) is a reliable treatment alternative to restore lost functions. Tooth-supported fixed prosthetic restorations (FDPs, SCs) are influenced by multiple combined general and local factors that may affect the risk of complication and failure. Recognizing risk factors is important in treatment planning, and will help the clinician optimize treatment outcomes. This will also be beneficial for both the patient and society from a cost-effective aspect, as a reduction in complications and failures reduces costs. Several factors have been suggested to impact the survival and failure rates of FDPs and SCs, but there is still limited evidence concerning the clinical outcomes of FDPs and SCs when subjected to a combination of multiple factors in a clinical setting. The aim of the present thesis was to evaluate whether the survival and failure rates of full-coverage tooth-supported fixed prosthetic restorations (FDPs, SC) are influenced by general and/or local factors. This thesis is based on a systematic review (Paper I) and three retrospective studies (Papers II, III, and IV). In Study I, PubMed, Web of Science and ScienceDirect databases were searched and manual searches were conducted to identify clinical human studies reporting on full-coverage tooth-supported FDPs and SCs. Cumulative survival rate (CSR) was calculated over the maximal period of follow-up reported, in a life-table survival analysis. Seventeen studies fulfilled the inclusion criteria. The highest 5-year survival rate was observed for all-ceramic and metal–ceramic SCs on vital teeth 97.8% (95%CI [97.1– 98.5%]), and all-ceramic SCs on non-vital teeth with fiber post 99.1% (95% CI [97.7– 100.4%]). Metal–ceramic SCs on vital teeth 97.5% (95% CI[96.8–98.3%]) showed a statistically significant higher estimated 5-year survival rate compared to metal–ceramic SCs with cast metal post 94.5% (95% CI [93.3–95.8%], p <0.001) and fiber post 95.1% (95% CI [93.4–96.6%], p <0.007), respectively. For FDPs, the 5-year survival rate was higher for metal–ceramic FDPs on vital abutments 96.9% (95% CI [95.5–98.4%]), compared to FDPs retained by non-vital abutment(s) with cast metal posts 94.3% (95% CI [89.3–99.3%]). The difference was not statistically significant. Tooth vitality is suggested to contribute positively to the survival of SCs. The results are, however, limited by the small number of studies and the presence of uncontrolled cofounding clinical variables. In the retrospective studies II, III, and IV, dental records archives and the digital journals of all patients at the Faculty of Odontology, Malmö University, Sweden were reviewed to identify patients rehabilitated with full-coverage toothsupported FDPs and SCs. Cox regression was used to evaluate the associations between clinical covariates and prosthesis failure. The CSR was similar for FDPs and SCs after 5 years of function. CSR was higher for SCs compared to FDPs after 10, 15, and 20 years of function. Smoking, type of prosthesis material, and bruxism significantly influenced the survival of FDPs, whereas abutment vitality, position of the non-vital abutment, or prosthesis length did not show any significant influence on the occurrence of FDP failure. The survival of SC was influenced by anterior placement, non-vital abutments, and bruxism, while the patient’s age and sex, the location of the crowns in relation to the jaws, the type of tooth, the presence of post and core, and the type of crown material, treatment providers, or smoking did not show significant effects on the survival of SC.In summary, within the limitations of the review and retrospective studies, bruxism, smoking, and type of prosthesis material are suggested to contribute toFDP failure. Anterior placement, non-vital abutments, and bruxism are factors increasing the rate of SC failure.

Place, publisher, year, edition, pages
Malmö: Malmö University Press, 2023. , p. 88
Series
Malmö University Odontological Dissertations, ISSN 1650-6065
National Category
Dentistry
Identifiers
URN: urn:nbn:se:mau:diva-58360DOI: 10.24834/isbn.9789178773558ISBN: 978-91-7877-354-1 (print)ISBN: 978-91-7877-355-8 (electronic)OAI: oai:DiVA.org:mau-58360DiVA, id: diva2:1739573
Public defence
2023-03-31, Aulan, Odontologiska fakulteten, Smedjeg. 16, Malmö, 09:15
Opponent
Supervisors
Note

Paper I in dissertation as manuscript with title "The longevity of fixed prosthetic restorations on vital and non-vital teeth: A systematic review"

Available from: 2023-02-27 Created: 2023-02-27 Last updated: 2023-08-18Bibliographically approved
List of papers
1. Survival of fixed prosthetic restorations on vital and nonvital teeth: A systematic review
Open this publication in new window or tab >>Survival of fixed prosthetic restorations on vital and nonvital teeth: A systematic review
2024 (English)In: Journal of Prosthodontics, ISSN 1059-941X, E-ISSN 1532-849X, Vol. 33, no 2, p. 110-122Article, review/survey (Refereed) Published
Abstract [en]

PURPOSE: To evaluate the survival rate of full-coverage tooth-supported fixed prosthetic restorations, single crowns (SCs), and fixed dental prostheses (FDPs), taking into consideration the potential influence of tooth-vitality, presence and type of post, and type of prosthetic restoration material.

MATERIALS AND METHODS: In October 2022, two authors independently conducted a search in PubMed, Web of Science, and Scopus electronic databases as well as a hand search to identify clinical human studies on full-coverage SCs and FDPs supported by vital and/or non-vital abutments and/or a combination of both, with a minimum observation period of 24 months.

RESULTS: Out of 4198 studies identified through the database search and 22 through hand searching, 26 studies fulfilled the inclusion criteria and were included in the analysis of the present systematic review. Included studies scored six points and more according to Newcastle-Ottawa Scale (NOS). The highest estimated 5-year survival rate was observed for (metal-ceramic and all-ceramic) SCs on vital teeth (98.3%; 95% CI [98.1, 98.6%]) and all ceramic SCs on non-vital teeth with fiber post (95.0%; 95% CI [94.5-95.4%]). Metal-ceramic SCs on vital teeth (97.1%; 95% CI [95.6-98.7%]) showed a statistically significant higher estimated 5-year survival rate compared to metal-ceramic SCs with cast metal post (90.7%; 95% CI [87.4-94.0%], P < 0.001), fiber post (91.3%; 95% CI [90.9-91.6%], P < 0.001) and without post (85.7%; 95% CI [80.7, 90.6%], P < 0.032). All-ceramic SCs with fiber post had a statistically significant higher estimated 5-year survival rate (95.0%; 95% CI [94.5-95.4%]) compared to metal-ceramic SCs on non-vital teeth with fiber post (91.3%; 95% CI [90.9-91.6%], P < 0.001). SCs (all-ceramic and metal-ceramic) with fiber post had a statistically significantly higher estimated 5-year survival rate of (92.7%; 95% CI [92.4-92.9%]) than SCs made of metal-ceramic and retained by cast metal post (90.7%; 95% CI [87.4-94.0%], P < 0.001). For FDPs, the 5-year survival rate was significantly higher for FDPs on vital abutments (84.9%; 95% CI [75.9, 93.9%]) compared to FDPs retained by non-vital abutment/s (81.3%; 95% CI [80.3, 82.2%], P = 0.049) irrespective to presence, type of post, and FDPs material. The results are limited by the limited number of studies and the presence of uncontrolled confounding clinical variables.

CONCLUSIONS: Within the limitations of the study, tooth vitality is suggested to contribute positively to the survival of SCs and FDPs.

Place, publisher, year, edition, pages
John Wiley & Sons, 2024
Keywords
post and core, single crown and fixed dental prosthesis, survival and failure rates, systematic review, tooth vitality, tooth-supported prosthesis
National Category
Dentistry
Identifiers
urn:nbn:se:mau:diva-61981 (URN)10.1111/jopr.13735 (DOI)001045218000001 ()37455556 (PubMedID)2-s2.0-85167659757 (Scopus ID)
Available from: 2023-08-18 Created: 2023-08-18 Last updated: 2024-02-27Bibliographically approved
2. Long-term retrospective clinical study of tooth-supported fixed partial dentures: A multifactorial analysis
Open this publication in new window or tab >>Long-term retrospective clinical study of tooth-supported fixed partial dentures: A multifactorial analysis
2023 (English)In: Journal of Prosthodontic Research, ISSN 1883-1958, E-ISSN 2212-4632, Vol. 67, no 2, p. 238-245Article in journal (Refereed) Published
Abstract [en]

PURPOSE: To assess the influence of several factors on the survival of tooth-supported fixed partial dentures (FPDs) with vital and non-vital abutments.

MATERIALS AND METHODS: The present retrospective cohort study was based on the records of patients treated with 3-to-7-unit tooth-supported FPDs with a minimum follow-up time of 6 months after prosthesis delivery. Cumulative survival rate (CSR) was calculated over the maximum follow-up period. Cox regression models were used to evaluate the association between the clinical covariates and prosthesis failure.

RESULTS: A total of 331 FPDs in 229 patients were included. The CSRs were 90.1% and 77.6% after 5 and 10 years and 67.9% and 52.1% after 15 and 20 years, respectively. Tooth-supported FPD failure was more prevalent within the first years of prosthesis delivery. Loss of one or more abutment teeth and loss of prosthesis retention were the main reasons for failure. Smoking and type of prosthesis material significantly influenced the survival of FPDs. Abutment vitality, position of the non-vital abutment, or prosthesis length did not show any significant influence on the occurrence of prosthesis failure.

CONCLUSION: Smoking and the type of prosthesis material are suggested to contribute to an increased rate of FPD failure irrespective of abutment vitality.

Place, publisher, year, edition, pages
Japan Prosthodontic Society, 2023
Keywords
Post and Core, Prosthesis failure, Prosthesis material, Smoking, Survival rate
National Category
Dentistry
Identifiers
urn:nbn:se:mau:diva-55213 (URN)10.2186/jpr.JPR_D_21_00222 (DOI)000943346200001 ()36031347 (PubMedID)2-s2.0-85149769941 (Scopus ID)
Available from: 2022-09-28 Created: 2022-09-28 Last updated: 2024-02-05Bibliographically approved
3. Retrospective Study Comparing Clinical Outcomes of Fixed Dental Prostheses in Matched Groups of Bruxer and Nonbruxer Patients
Open this publication in new window or tab >>Retrospective Study Comparing Clinical Outcomes of Fixed Dental Prostheses in Matched Groups of Bruxer and Nonbruxer Patients
2022 (English)In: International Journal of Dentistry, ISSN 1687-8728, E-ISSN 1687-8736, Vol. 2022, article id 6818170Article in journal (Refereed) Published
Abstract [en]

Background: Tooth-supported fixed dental prosthesis (FDP) is one of the most reliable treatment options to replace missing teeth. The longevity of the treatment could, however, be affected by several general and local factors, especially bruxism.

Objective: To investigate the influence of bruxism on the long-term survival of tooth-supported FDPs in bruxers compared to a matched group of nonbruxers, taking several clinical variables into account.

Materials and methods: The present retrospective cohort study was based on records of patients treated with 3-7-unit tooth-supported FDPs with a minimum follow-up time of 6 months after prosthesis delivery. The criteria for the diagnosis of "possible" and "probable" sleep or awake bruxism were used. A matched group of nonbruxers was selected on the basis of similarities in four factors, patients' gender and age, number of prosthetic units of the FDPs, and follow-up time. The paired-samples t-test or Wilcoxon signed rank test were used to compared mean values between the two groups. Contingency tables of categorical data were analyzed by McNemar's test.

Results: The cohort group consisted of 62 noncantilevered FDPs in each group, followed up for a mean of 110.1 and 106.5 months (bruxers and nonbruxers, respectively). Tooth-supported FDPs in bruxers presented significantly higher failure rate than in nonbruxers (32.3% vs. 25.8%, respectively; p = 0.001). Loss of retention and tooth loss were the main reasons for failures in both groups. For nonsmokers, the FDP failure rate was higher in nonbruxers. Technical and biological complications were significantly more prevalent in bruxers compared to nonbruxers.

Conclusions: Bruxism is suggested to increase technical and biological complications and FDP failure.

Place, publisher, year, edition, pages
Hindawi Publishing Corporation, 2022
National Category
Dentistry
Identifiers
urn:nbn:se:mau:diva-51010 (URN)10.1155/2022/6818170 (DOI)000933106300001 ()35386548 (PubMedID)2-s2.0-85128437081 (Scopus ID)
Available from: 2022-04-08 Created: 2022-04-08 Last updated: 2024-02-05Bibliographically approved
4. Retrospective clinical study of tooth-supported single crowns: A multifactor analysis
Open this publication in new window or tab >>Retrospective clinical study of tooth-supported single crowns: A multifactor analysis
2022 (English)In: European Journal of Oral Sciences, ISSN 0909-8836, E-ISSN 1600-0722, Vol. 130, no 4, article id e12871Article in journal (Refereed) Published
Abstract [en]

The purpose of the study was to investigate the influence of multiple factors on the survival of tooth-supported single crowns and assess the biological and technical complications. This retrospective study included patients rehabilitated with single crowns with a minimum follow-up time of 6 months after delivery. The cumulative survival rate was calculated over the maximum period of follow-up time and reported in a life-table survival analysis. Univariate and multivariate Cox regression was used to evaluate the associations between clinical covariates and crown failure. The included cohort group consisted of 1037 single crowns delivered in 401 patients and followed for a mean of 134.8 ± 80.2 months. Cumulative survival rate was 89.9% and 80.9% after 5 and 10 years and 70.5% and 61.8% after 15 and 20 years, respectively. The main reasons for single crown failure were loss of retention, tooth loss, and fracture. Anterior placement, non-vital abutments, and bruxism significantly influenced the survival of single crowns. The survival of single crowns was not influenced by patient's age and sex, location of the crowns in relation to the jaws, type of tooth, presence of post and core, and type of crown material, treatment providers, or smoking. Anterior placement, non-vital abutments, and bruxism are factors suggested to increase the risk of single crown failure and the prevalence of technical and biological complications.

Place, publisher, year, edition, pages
John Wiley & Sons, 2022
Keywords
post and core, single crown, survival rate, technical and biological complications, tooth vitality
National Category
Dentistry
Identifiers
urn:nbn:se:mau:diva-52206 (URN)10.1111/eos.12871 (DOI)000799960400001 ()35613306 (PubMedID)2-s2.0-85130543424 (Scopus ID)
Available from: 2022-06-08 Created: 2022-06-08 Last updated: 2024-06-17Bibliographically approved

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