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Management of orofacial manifestations of juvenile idiopathic arthritis: Interdisciplinary consensus-based recommendations.
Section of Orthodontics, Aarhus University, Aarhus, Denmark.
Department of Plastic and Oral Surgery, Boston Children's Hospital, Boston, Massachusetts.
Division of Oral and Maxillofacial Surgery, Departments of Surgery and Pediatrics, Emory University School of Medicine, Atlanta, Georgia.
Section of Orthodontics and Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark.
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2023 (English)In: Arthritis & Rheumatology, ISSN 2326-5191, E-ISSN 2326-5205, Vol. 75, no 1, p. 4-14Article, review/survey (Refereed) Published
Abstract [en]

OBJECTIVES: Involvement of the temporomandibular joint (TMJ) is common in juvenile idiopathic arthritis (JIA). TMJ arthritis can lead to orofacial symptoms, dysfunction and dentofacial deformity with negative impact on quality of life. Management involves interdisciplinary collaboration. No current recommendations exist to guide clinical management.

OBJECTIVES: 1) To develop consensus-based interdisciplinary recommendations for management of orofacial manifestations of JIA. 2) To create a future research agenda related to management of TMJ arthritis in children with JIA.

METHODS: The recommendations were developed using online surveying of relevant stakeholders, systematic literature review, evidence-informed generation of recommendations during two consensus-meetings, and Delphi study iterations involving external experts. The process included disciplines involved in the care of orofacial manifestations of JIA: Pediatric rheumatology, radiology, orthodontics, oral and maxillofacial surgery, orofacial pain specialists and pediatric dentistry. Recommendations were accepted if agreement was >80% during a final Delphi study.

RESULTS: Three overarching management principles and 12 recommendations for interdisciplinary management of orofacial manifestations of JIA were outlined. The 12 recommendations pertained to: diagnosis (n=4), treatment of TMJ arthritis (active TMJ inflammation) (n=2), treatment of TMJ dysfunction and symptoms (n=3), treatment of arthritis-related dentofacial deformity (n=2), and other related aspects to JIA (n=1). Additionally, a future interdisciplinary research agenda was developed.

CONCLUSIONS: These are the first interdisciplinary recommendations to guide clinical management of TMJ JIA. The 3 overarching principles and 12 recommendations fill an important gap in current clinical practice. They emphasize the importance of an interdisciplinary approach to diagnosis and management of orofacial manifestations of JIA. This article is protected by copyright. All rights reserved.

Place, publisher, year, edition, pages
John Wiley & Sons, 2023. Vol. 75, no 1, p. 4-14
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Dentistry
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URN: urn:nbn:se:mau:diva-55211DOI: 10.1002/art.42338ISI: 000890606100001PubMedID: 36041065Scopus ID: 2-s2.0-85139428988OAI: oai:DiVA.org:mau-55211DiVA, id: diva2:1708473
Available from: 2022-11-04 Created: 2022-11-04 Last updated: 2023-09-08Bibliographically approved

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Alstergren, Per

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