Malmö University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Patient perspectives on depot buprenorphine treatment for opioid addiction: a qualitative interview study
Malmö University, Faculty of Health and Society (HS), Department of Social Work (SA).ORCID iD: 0000-0002-1601-2706
Malmö University, Faculty of Health and Society (HS), Department of Social Work (SA).ORCID iD: 0000-0002-2339-2647
Department of Psychiatry in Linköping and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
2022 (English)In: Substance Abuse Treatment, Prevention, and Policy, E-ISSN 1747-597X, Vol. 17, no 1, article id 40Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Recently developed buprenorphine depot injections have the potential to reduce risk for diversion and misuse, and to increase adherence with fewer visits for supervised intake. However, it is unclear how patients perceive this new form of medication. The purpose of this study was to explore patients' experiences of depot injections and their reasons for continuing, discontinuing, or declining depot injection treatment.

METHODS: We conducted semi-structured qualitative interviews with 32 people, 14 of whom had ongoing depot injection treatment, 11 who had discontinued depot-injections and switched to other medication and seven who had declined treatment with depot formulations. Interviews were transcribed, coded, and analysed using NVivo, based on this overall stratification into three participant groups.

RESULTS: The main categories relate to the effects and side effects of the depot formulation, social and practical factors, psychological benefits and disadvantages, and interactions with treatment staff. Social and practical factors were of importance for choosing depot formulations, such as increased freedom and their making it easier to combine treatment with work and family life, as well as psychological advantages including "feeling normal". Initial withdrawal symptoms that resolved themselves after a number of injections were reported by most participants. Reliable information and patient-staff relationships characterized by trust helped patients to cope with these initial problems. Those who discontinued treatment often did so near the beginning of the treatment, reporting withdrawal symptoms and insufficient effects as the main reasons. Coercion and insufficient information contributed to a negative pharmaceutical atmosphere at one of the clinics, which may have adversely influenced perceptions of depot formulations and decreased willingness to accept and continue treatment.

CONCLUSIONS: Buprenorphine depot injections may have social, practical, and psychological benefits compared to other formulations. However, depot injections are not perceived as an attractive option by all patients. Trust, consistent and adequate information, and awareness of the implications of the pharmaceutical atmosphere should be considered when introducing new medications.

Place, publisher, year, edition, pages
BioMed Central, 2022. Vol. 17, no 1, article id 40
Keywords [en]
Depot injections, Opioid addiction, Pharmaceutical atmosphere, Qualitative interviews, Treatment
National Category
Social Work
Identifiers
URN: urn:nbn:se:mau:diva-52205DOI: 10.1186/s13011-022-00474-2ISI: 000800128300001PubMedID: 35614466Scopus ID: 2-s2.0-85130699243OAI: oai:DiVA.org:mau-52205DiVA, id: diva2:1665848
Available from: 2022-06-08 Created: 2022-06-08 Last updated: 2024-02-05Bibliographically approved

Open Access in DiVA

fulltext(868 kB)68 downloads
File information
File name FULLTEXT01.pdfFile size 868 kBChecksum SHA-512
18ce89a950146623f9b23fbd18f4ac862f810b87af2e51d1b2d4d3b2e0e536408643071836bfc92edae7cb0aab9fbd8c42c577c0cda5ef6c39006034e8a134b8
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMedScopus

Authority records

Johnson, BjörnLiahaugen Flensburg, Olivia

Search in DiVA

By author/editor
Johnson, BjörnLiahaugen Flensburg, Olivia
By organisation
Department of Social Work (SA)
In the same journal
Substance Abuse Treatment, Prevention, and Policy
Social Work

Search outside of DiVA

GoogleGoogle Scholar
Total: 68 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 113 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf