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Influence of fresh-frozen allogeneic bone grafts architecture on its incorporation: radiographic and histomorphometric comparison to the gold-standard
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2013 (Engelska)Ingår i: Clinical Oral Implants Research, ISSN 0905-7161, E-ISSN 1600-0501, Vol. 24, nr s9, s. 54-54, artikel-id 117Artikel i tidskrift, Meeting abstract (Övrigt vetenskapligt)
Abstract [en]

Background: The influence of fresh-frozen block bone allograft architecture on its incorporation and dimensional remodeling remains unclear. Aim/Hypothesis: To compare cortical (AL-C) and corticocancellous (AL-CC) fresh-frozen block bone allografts to cortical block bone autografts (AT) in terms of histomorphometrical graft incorporation and radiographic dimensional remodeling, 6–8 months after grafting for anterior maxillary ridge augmentation. Material and methods: Twenty-four patients, requiring ridge augmentation in the anterior maxilla prior to implant placement, were treated with AT, AL-C or AL-CC (eight patients per graft type). During implant installation surgery, 6–8 months after grafting, cylindrical biopsies were harvested perpendicularly to the lateral aspect of the augmented alveolar ridge; the relative volumes of vital and necrotic bone, and soft tissue, were histomorphometrically estimated. Furthermore, all patients were examined with CBCT prior to surgery, and 14 days and 6–8 months after grafting. Amount of augmentation and dimensional block graft remodeling over time were evaluated by comparing planimetric measurements of the alveoral ridge made on serial, parasagittal, CBCT sections generated throughout the augmentation area, for each patient. Average values were calculated for each graft type; comparisons among groups and observation times were performed using repeated-measures ANOVA and Tukey post-hoc test. P was set at <0.05. Results: Histomorphometrical analysis showed that the AL-CC group had the smallest amount of necrotic bone (38.2 12.1%) compared to AT (56.7 25.9%, P < 0.05) and AL-C (83.7 10.8%, P < 0.0001). AL-CC showed the largest amount of soft tissues (52.5 11.7%) compared to AT (18.1 17.1%, P < 0.0001) and AL-C (12.3 8.5%, P < 0.0001). Larger amounts of viable bone were found in the AT-treated group (25.1 11.2%) compared to AL-CC and AL-C groups (9.3 3.8% and 3.9 4.6%, respectively; P < 0.0001). The radiographic evaluation showed that all type of grafts resulted in a significant increase in alveolar ridge dimensions, with no significant differences among the groups at the various observation times. However, graft resorption in the AL-CC group was significantly larger (P < 0.05) compared to that observed in the AT and AL-C groups. Conclusions and clinical implications: AL block bone graft architecture influences their incorporation and dimensional remodeling. Corticocancellous AL blocks seem to show larger resorption over time, while cortical blocks seem to show the least amounts of vital bone 6–8 months after grafting. Only a small portion of the AL block consists of vital bone 6–8 months after grafting.

Ort, förlag, år, upplaga, sidor
John Wiley & Sons, 2013. Vol. 24, nr s9, s. 54-54, artikel-id 117
Nationell ämneskategori
Odontologi
Identifikatorer
URN: urn:nbn:se:mau:diva-15635DOI: 10.1111/clr.12246Lokalt ID: 18424OAI: oai:DiVA.org:mau-15635DiVA, id: diva2:1419157
Konferens
European Association of Osseointegration (EAO), Dublin, Ireland (2013)
Tillgänglig från: 2020-03-30 Skapad: 2020-03-30 Senast uppdaterad: 2022-06-27Bibliografiskt granskad

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Förlagets fulltexthttp://www.colloquium.eu/congres/14EAO/docs/EAO_Final_Programme_2013.pdf

Person

Stavropoulos, Andreas

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Stavropoulos, Andreas
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Clinical Oral Implants Research
Odontologi

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Totalt: 86 träffar
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