Bacterial proteases are a driving force for the inflammatory responses involved in both periodontitis and cardiovascular disease. The goal of this project is to develop prototypes of advanced technological tools based on an array of biomarkers (bacterial proteases and inflammatory mediators) to aid the identification of individuals at risk of severe alveolar bone loss disease prediction and treatment of periodontal disease and associated inflammatory disorders. Candidate biomarkers identified in experimental models will be validated in clinical investigations.

Participating organisations: Enzymatica AB, Alzecure AB, Capsenze AB, PEAS Institut AB