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  • 1. Valldeperas, Maria
    et al.
    Salis, Andrea
    Barauskas, Justas
    Tiberg, Fredrik
    Arnebrant, Thomas
    Malmö University, Faculty of Health and Society (HS), Department of Biomedical Science (BMV).
    Razumas, Valdemaras
    Monduzzi, Maura
    Nylandert, Tommy
    Enzyme encapsulation in nanostructured self-assembled structures: Toward biofunctional supramolecular assemblies2019In: Current Opinion in Colloid & Interface Science, ISSN 1359-0294, E-ISSN 1879-0399, Vol. 44, p. 130-142Article, review/survey (Refereed)
    Abstract [en]

    Enzymes have come into use for many new applications outside their natural biological environment, taking advantage of their high efficiency and selectivity as biocatalysts. Such new application often requires encapsulation to preserve the structure and activity of the enzyme, but also to regulate and control the activity. Here, we will discuss two types of encapsulation, soft matrices consisting of polar lipid liquid crystals and hard ordered mesoporous silica matrices. For both types of matrices, the challenge is to control the pore size of the matrices and the interaction with the matrix interface. Here, the polar lipid liquid crystals offer larger flexibility than silica, but on the other hand, it is considerably more sensitive to the environment.

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