Publikationer från Malmö universitet
Ändra sökning
Avgränsa sökresultatet
1 - 32 av 32
RefereraExporteraLänk till träfflistan
Permanent länk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Träffar per sida
  • 5
  • 10
  • 20
  • 50
  • 100
  • 250
Sortering
  • Standard (Relevans)
  • Författare A-Ö
  • Författare Ö-A
  • Titel A-Ö
  • Titel Ö-A
  • Publikationstyp A-Ö
  • Publikationstyp Ö-A
  • Äldst först
  • Nyast först
  • Skapad (Äldst först)
  • Skapad (Nyast först)
  • Senast uppdaterad (Äldst först)
  • Senast uppdaterad (Nyast först)
  • Disputationsdatum (tidigaste först)
  • Disputationsdatum (senaste först)
  • Standard (Relevans)
  • Författare A-Ö
  • Författare Ö-A
  • Titel A-Ö
  • Titel Ö-A
  • Publikationstyp A-Ö
  • Publikationstyp Ö-A
  • Äldst först
  • Nyast först
  • Skapad (Äldst först)
  • Skapad (Nyast först)
  • Senast uppdaterad (Äldst först)
  • Senast uppdaterad (Nyast först)
  • Disputationsdatum (tidigaste först)
  • Disputationsdatum (senaste först)
Markera
Maxantalet träffar du kan exportera från sökgränssnittet är 250. Vid större uttag använd dig av utsökningar.
  • 1. Astvaldsdottir, Alfheiour
    et al.
    Naimi-Akbar, Aron
    Davidson, Thomas
    Brolund, Agneta
    Lintamo, Laura
    Granath, Anna Attergren
    Tranæus, Sofia
    Malmö högskola, Odontologiska fakulteten (OD).
    Östlund, Pernilla
    Malmö högskola, Odontologiska fakulteten (OD).
    Arginine and Caries Prevention: A Systematic Review2016Ingår i: Caries Research, ISSN 0008-6568, E-ISSN 1421-976X, Vol. 50, nr 4, s. 383-393Artikel, forskningsöversikt (Refereegranskat)
    Abstract [en]

    Objectives: To evaluate the available evidence that the use of arginine-containing dental care products prevents the development of new caries lesions and the progression of existing lesions. Search Methods: We performed a systematic literature search of databases including PubMed, the Cochrane Library and EMBASE. Selection Criteria: We selected randomized controlled trials of treatment with arginine in fluoride-containing dental products measuring dental caries incidence or progression in children, adults and elderly subjects. Data Collection and Analysis: Two review authors independently assessed trials for risk of bias and evaluated overall study quality using the GRADE classification. Main Results: Due to conflicts of interest and weak transferability to Swedish conditions, no conclusions can be drawn from studies on the effects of arginine-fluoride toothpaste in children. Arginine-containing toothpaste costs about 40% more than basic fluoride toothpaste; to determine whether it is more cost-effective, the higher cost must be considered in relation to any additional caries-preventive effect. The literature review also disclosed some questionable research ethics: in several of the studies, the children in the control group used non-fluoride toothpaste. Toothpaste without fluoride is not as effective against dental caries as the standard treatment - fluoride toothpaste - which has a well -documented effect. This contravenes the fundamental principles of research ethics. Conclusion: At present there is insufficient evidence in support of a caries-preventive effect for the inclusion of arginine in toothpastes. More rigorous studies, and studies which are less dependent on commercial interests, are required. (C) 2016 S. Karger AG, Basel

  • 2. Axelsson, Susanna
    et al.
    Davidsson, Thomas
    Gynther, Göran
    Helgesson, Gert
    Hultin, Margareta
    Håkansson, Kickan
    Jemt, Torsten
    Kedebring, Therese
    Lekholm, Ulf
    Lindholm, Jonas
    Nilner, Krister
    Malmö högskola, Odontologiska fakulteten (OD).
    Nordenram, Gunilla
    Norlund, Anders
    Sunnegårdh-Grönberg, Karin
    Tranæus, Sofia
    Rohlin, Madeleine
    Malmö högskola, Odontologiska fakulteten (OD).
    Tandförluster: En systematisk litteraturöversikt2010Rapport (Övrigt vetenskapligt)
  • 3. Bergentholtz, Gunnar
    et al.
    Axelsson, Susanna
    Davidson, Thomas
    Frisk, Fredrik
    Hakeberg, Magnus
    Helgesson, Gert
    Håkanson, Kickan
    Kedebring, Therese
    Kvist, Thomas
    Lindblom, Jonas
    Mejàre, Ingegerd
    Malmö högskola, Odontologiska fakulteten (OD).
    Norlund, Anders
    Petersson, Arne
    Malmö högskola, Odontologiska fakulteten (OD).
    Portenier, Isabelle
    Sandberg, Hans
    Tranæus, Sofia
    Rotfyllning: en systematisk litteraturöversikt2010Rapport (Övrigt vetenskapligt)
    Ladda ner fulltext (pdf)
    fulltext
  • 4.
    Bohm-Starke, Nina
    et al.
    Division of Obstetrics and Gynecology, Department of Clinical Sciences, Karolinska Institutet Danderyd Hospital, 171 77 Stockholm, Sweden.
    Pukall, Caroline
    Department of Psychology, Queen’s University, Kingston, ON K7L 3N6, Canada.
    Österberg, Marie
    Swedish Agency for Health Technology Assessment and Assessment of Social Services, Stockholm, 102 33, Sweden.
    Ahlberg, Maria
    Swedish Agency for Health Technology Assessment and Assessment of Social Services, Stockholm, 102 33, Sweden.
    Jonsson, Ann Kristine
    Swedish Agency for Health Technology Assessment and Assessment of Social Services, Stockholm, 102 33, Sweden.
    Tranæus, Sofia
    Malmö universitet, Odontologiska fakulteten (OD). Swedish Agency for Health Technology Assessment and Assessment of Social Services, Stockholm, 102 33, Sweden.
    Kempe, Susanna
    Swedish Agency for Health Technology Assessment and Assessment of Social Services, Stockholm, 102 33, Sweden.
    Hellberg, Christel
    Swedish Agency for Health Technology Assessment and Assessment of Social Services, Stockholm, 102 33, Sweden.
    Development of a core outcome set for treatment studies for provoked vestibulodynia.2024Ingår i: Journal of Sexual Medicine, ISSN 1743-6095, E-ISSN 1743-6109, artikel-id qdae035Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND: There is an inconsistency in treatment outcomes used in clinical trials for provoked vestibulodynia (PVD), which makes it impossible to compare the effects of different interventions.

    AIM: In this study, we completed the first step in creating a core outcome set (COS), defining what outcomes should be measured in clinical trials for PVD.

    METHODS: Identification of outcomes used in studies was done by extracting data from clinical trials in a recently published systematic review and via review of clinical trials for PVD registered on ClinicalTrials.gov. The COS process consisted of 2 rounds of Delphi surveys and a consensus meeting, during which the final COS was decided through a modified nominal group technique.

    OUTCOMES: Consensus on what outcomes to include in a COS for PVD.

    RESULTS: Forty scientific articles and 92 study protocols were reviewed for outcomes. Of those, 36 articles and 25 protocols were eligible, resulting in 402 outcomes, which were then categorized into 63 unique outcomes. Participants consisted of patients, relatives/partners of patients, health care professionals, and researchers. Out of 463 who registered for participation, 319 and 213 responded to the first and second surveys, respectively. The consensus meeting consisted of 18 members and resulted in 6 outcomes for the COS to be measured in all treatment trials regardless of intervention: insertional pain (nonsexual), insertional pain (sexual), provoked vulvar pain by pressure/contact, pain-related interference on one's life, pain interference on sexual life, and sexual function.

    CLINICAL IMPLICATIONS: Critical outcomes to be measured in clinical trials will allow for accurate comparison of outcomes across treatment interventions and provide solid treatment recommendations.

    STRENGTHS AND LIMITATIONS: The major strengths of the study are the adherence to methodological recommendations and the intentional focus on aspects of diversity of participating stakeholders (eg, status such as patients with lived experience and researchers, inclusiveness with respect to sexual identity), the latter of which will allow for broader application and relevance of the COS. Among the limitations of the study are the low rate of participants outside North America and Europe and the lower response rate (about 50%) for the second Delphi survey.

    CONCLUSION: In this international project, patients, health care professionals, and researchers have decided what critical outcomes are to be used in future clinical trials for PVD. Before the COS can be fully implemented, there is also a need to decide on how and preferably when the outcomes should be measured.

  • 5.
    Cederlund, Andreas
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Lundgren, Frida
    Tranæus, Sofia
    Malmö högskola, Odontologiska fakulteten (OD).
    Norlund, Anders
    Caries treatment in Swedish adults: effectiveness, costs and equity. A 4-year follow-up study of data from the Swedish national dental health register2016Ingår i: Swedish Dental Journal, ISSN 0347-9994, Vol. 40, nr 2, s. 223-234Artikel i tidskrift (Refereegranskat)
    Abstract [sv]

    Planering och styrning av tandvård på nationell nivå bör baseras på utvärderingar av jämlik fördelning, effektivitet och kostnader. Med inrättandet av tandhälsoregistret vid Socialstyrelsen öppnas möjligheter för studier av tandvårdens processer och resultat. Syftet med studien var att utifrån två identifierade kohorter longitudinellt följa och analysera frekvens och kostnader för ny fyllning eller tandkrona på tidigare restaurerad tand (omgörningar) samt relationen mellan förebyggande tandvårdsåtgärder i relation till reparativ och restaurativ tandvård orsakad av karies. Med hjälp av tandhälsoregistret studerades två kohorter omfattande den vuxna befolkningen. En longitudinell modell användes för uppföljning. I den första kohorten följdes 1 878 887 tänder hos 1 088 923 patienter mellan 42 och 48 månader. I den andra kohorten följdes 1 703 147 patienter under en period av mellan 48 och 54 månader. Fördelning av tandvård för olika åldersgrupper visade att kohorterna var representativa för hela patientgruppen. Fördelning av tandvårdsbesök varierade mellan 140 och 160 räknat per 1 000 invånare trots olika geografiska förutsättningar. Resultaten baserade på den första kohorten visar att 76% av tänderna inte fick någon ytterligare åtgärd med fyllning eller tandkrona under uppföljningsperioden, och att för resterande 24% av tänderna fick 77% endast en ny åtgärd. Det förelåg ingen könsskillnad, däremot skillnader på upp till tre intakta tänder mellan olika regioner. Resultat från den andra kohorten visade heller ingen könsskillnad. De genomsnittliga kostnaderna för reparativa åtgärder på grund av karies ökade gradvis i relation till ökade kostnader för förebyggande åtgärder. Vidare var kostnaderna för reparativa åtgärder lägre ju längre tid som följde mellan förebyggande åtgärder. Det nationella tandhälsoregistret utgör en värdefull källa för forskning om tandvård. Longitudinella registerdata för reparationer och preventiva åtgärder kan användas för att studera effektivitet, kostnader och jämlik fördelning av tandvård. Resultaten har en potential för förbättrad styrning av tandvården.

  • 6. Chiang, Huei-Min
    et al.
    Tranæus, Sofia
    Malmö universitet, Odontologiska fakulteten (OD).
    Sunnegårdh-Grönberg, Karin
    Caries as experienced by adult caries active patients: a qualitative study2019Ingår i: Acta Odontologica Scandinavica, ISSN 0001-6357, E-ISSN 1502-3850, Vol. 77, nr 1, s. 15-21Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    OBJECTIVE: In the western world, increased oral health has resulted in a skewed occurrence of caries disease where relatively few individuals now account for most caries disease. This study examines how adults with recurrent caries activity experience caries disease and treatment. MATERIALS AND METHODS: The study is based on qualitative data from individual interviews, which were subjected to qualitative content analysis. The interviews were semi-structured and thematic and an interview guide was used that consisted of two main areas with open ended questions. Meaning units were condensed and labelled with a code which preserved the core content of the reduced text. Codes were assigned to different subcategories according to their similarities or differences. Subcategories formed categories which describe the manifest content of the text. RESULTS: The domain "experience with caries" consisted of four subcategories that formed the main category Caries - an unwelcomed acquaintance. The domain "experience with caries treatment" consisted of three subcategories that formed the category Caries treatment - pain for gain. CONCLUSION: Comprehensive non-operative treatment and close follow-ups should precede restorations; this would probably gain insight in how to avoid new cavities to a greater extent. If to be supportive, information and advice about self-care given to individuals with recurrent cavities should be delivered with respect to the patient's feelings about their experience of dental caries.

    Ladda ner fulltext (pdf)
    FULLTEXT01
  • 7.
    Davidson, Thomas
    et al.
    Malmö universitet, Odontologiska fakulteten (OD). Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
    Blomma, Caroline
    Public Dental Service Östergötland, and Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
    Bågesund, Mats
    Center for Orthodontics and Pediatric Dentistry, Norrköping, and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
    Krevers, Barbro
    Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
    Vall, Martina
    Malmö universitet, Malmö universitetsbibliotek.
    Wärnberg Gerdin, Elisabeth
    Odontological Research Unit, Public Dental Service, Region Örebro County, Örebro, Sweden; School of Health and Medical Sciences, Örebro University, Örebro, Sweden.
    Tranæus, Sofia
    Malmö universitet, Odontologiska fakulteten (OD). Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden.
    Cost-effectiveness of caries preventive interventions: a systematic review2021Ingår i: Acta Odontologica Scandinavica, ISSN 0001-6357, E-ISSN 1502-3850, Vol. 79, nr 4, s. 309-320Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    OBJECTIVE: The primary purpose of this study was to assess the cost-effectiveness of caries preventive interventions.

    MATERIAL AND METHODS: A systematic review was conducted, following the PRISMA Statement. Four electronic databases were searched (final search 16 March 2020). Studies fulfilling the inclusion criteria were independently critically appraised, by two reviewers in parallel. Data from each included study were extracted and tabulated: the analysis used a narrative approach to present the results of the estimated cost-effectiveness.

    RESULTS AND CONCLUSIONS: Twenty-six publications fulfilled the inclusion criteria and were of low or moderate risk of bias. Ten publications were economic evaluations, directly based on empirical studies, and the other 16 were modelling studies. Most of the studies concerned interventions for children and the most common were analyses of fluoride varnish and risk-based programs. Some of the studies showed both reduced cost and improved outcomes, but most studies reported that the improved outcome came with an additional cost. The results disclosed several cost-effectiveness evaluations of caries preventive interventions in the literature, but these target primarily children at high risk. There is a scarcity of studies specifically targeting adults and especially the elderly.

    Ladda ner fulltext (pdf)
    fulltext
  • 8. Davidson, Thomas
    et al.
    Rohlin, Madeleine
    Malmö högskola, Odontologiska fakulteten (OD).
    Hultin, Margareta
    Jemt, Torsten
    Nilner, Krister
    Malmö högskola, Odontologiska fakulteten (OD).
    Sunnegardh-Gronberg, Karin
    Tranæus, Sofia
    Malmö högskola, Odontologiska fakulteten (OD).
    Nilsson, Mats
    Malmö högskola, Odontologiska fakulteten (OD).
    Reimbursement systems influence prosthodontic treatment of adult patients2015Ingår i: Acta Odontologica Scandinavica, ISSN 0001-6357, E-ISSN 1502-3850, Vol. 73, nr 6, s. 414-420Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objective. To evaluate the influence of reimbursement system and organizational structure on oral rehabilitation of adult patients with tooth loss. Materials and methods. Patient data were retrieved from the databases of the Swedish Social Insurance Agency. The data consisted of treatment records of patients aged 19 years and above claiming reimbursement for dental care from July 1, 2007 until June 30, 2009. Before July 1, 2008, a proportionately higher level of subsidy was available for dental care in patients 65 years and above, but thereafter the system was changed, so that the subsidy was the same, regardless of the patient's age. Prosthodontic treatment in patients 65 years and above was compared with that in younger patients before and after the change of the reimbursement system. Prosthodontic treatment carried out in the Public Dental Health Service and the private sector was also analyzed. Results. Data were retrieved for 722,842 adult patients, covering a total of 1,339,915 reimbursed treatment items. After the change of the reimbursement system, there was a decrease in the proportion of items in patients 65 years and above in relation to those under 65. Overall, there was a minimal change in the proportion of treatment items provided by the private sector compared to the public sector following the change of the reimbursement system. Conclusions. Irrespective of service provider, private or public, financial incentive such as the reimbursement system may influence the provision of prosthodontic treatment, in terms of volume of treatment.

  • 9. Frisk, Fredrik
    et al.
    Kvist, Thomas
    Axelsson, Susanna
    Bergenholz, Gunnar
    Davidson, Thomas
    Mejàre, Ingegerd
    Norlund, Anders
    Petersson, Arne
    Malmö högskola, Odontologiska fakulteten (OD).
    Sandberg, Hans
    Tranaeus, Sofia
    Hakeberg, Magnus
    Pulp exposures in adults: choice of treatment among Swedish dentists2013Ingår i: Swedish Dental Journal, ISSN 0347-9994, Vol. 37, nr 3, s. 153-160Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    This study comprises a survey of Swedish dentists'treatment preferences in cases of carious exposure of the dental pulp in adults.The survey was conducted as part of a comprehensive report on methods of diagnosis and treatment in endodontics, published in 2010 by the Swedish Council on Health Technology Assessment. A questionnaire was mailed to a random subsample of 2012 dental offices where one dentist at each office was requested to answer all questions. Each questionnaire contained one of three sets of questions about endodontic practice routines.Thus around one-third of the subsample received case-specific questions about treating carious exposure. Only general practitioners aged below 70 years were included.The final study sample comprised 412 participants.The dentists were presented with two case scenarios. In Case 1 a 22-year old patient had a deep carious lesion in tooth 36 and in Case 2 a 50-year old patient had a deep carious lesion in tooth 14.The participants were asked to nominate their treatment of choice: pulp capping, partial pulpotomy or pulpectomy. For Case 1, 17 per cent of the respondents selected pulpectomy; the corresponding rate for Case 2 was 47 per cent. Female gender and age group 25-49 years were predictive of selection of less invasive treatment options. However, according to recent guidelines (2011) from the National Board of Health and Wellfare, Swedish dentists are recommended to elect pulpectomy prior to pulp capping/partial pulpotomy when confronted with a tooth having a cariously exposed pulp in adults.

  • 10. Heintz, Emelie
    et al.
    Lintamo, Laura
    Hultcrantz, Monica
    Jacobson, Stella
    Levi, Ragnar
    Munthe, Christian
    Tranæus, Sofia
    Malmö högskola, Odontologiska fakulteten (OD).
    Östlund, Pernilla
    Malmö högskola, Odontologiska fakulteten (OD).
    Sandman, Lars
    Framework for systematic identification of ethical aspects of healthcare technologies: the SBU approach2015Ingår i: International Journal of Technology Assessment in Health Care, ISSN 0266-4623, E-ISSN 1471-6348, Vol. 31, nr 3, s. 124-130Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objectives: Assessment of ethical aspects of a technology is an important component of health technology assessment (HTA). Nevertheless, how the implementation of ethical assessment in HTA is to be organized and adapted to specific regulatory and organizational settings remains unclear. The objective of this study is to present a framework for systematic identification of ethical aspects of health technologies. Furthermore, the process of developing and adapting the framework to a specific setting is described. Methods: The framework was developed based on an inventory of existing approaches to identification and assessment of ethical aspects in HTA. In addition, the framework was adapted to the Swedish legal and organizational healthcare context, to the role of the HTA agency and to the use of non-ethicists. The framework was reviewed by a group of ethicists working in the field as well as by a wider set of interested parties including industry, interest groups, and other potential users. Results: The framework consists of twelve items with sub-questions, short explanations, and a concluding overall summary. The items are organized into four different themes: the effects of the intervention on health, its compatibility with ethical norms, structural factors with ethical implications, and long term ethical consequences of using the intervention. Conclusions: In this study, a framework for identifying ethical aspects of health technologies is proposed. The general considerations and methodological approach to this venture will hopefully inspire and present important insights to organizations in other national contexts interested in making similar adaptations.

  • 11. Hultcrantz, Monica
    et al.
    Rind, David
    Akl, Elie A.
    Treweek, Shaun
    Mustafa, Reem A.
    Iorio, Alfonso
    Alper, Brian S.
    Meerpohl, Joerg J.
    Murad, M. Hassan
    Ansari, Mohammed T.
    Katikireddi, Srinivasa Vittal
    Östlund, Pernilla
    Malmö högskola, Odontologiska fakulteten (OD).
    Tranæus, Sofia
    Malmö högskola, Odontologiska fakulteten (OD).
    Christensen, Robin
    Gartlehner, Gerald
    Brozek, Jan
    Izcovich, Ariel
    Schünemann, Holger
    Guyatt, Gordon
    The GRADE Working Group clarifies the construct of certainty of evidence2017Ingår i: Journal of Clinical Epidemiology, ISSN 0895-4356, E-ISSN 1878-5921, Vol. 87, s. 4-13Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objective: To clarify the grading of recommendations assessment, development and evaluation (GRADE) definition of certainty of evidence and suggest possible approaches to rating certainty of the evidence for systematic reviews, health technology assessments, and guidelines. Study Design and Setting: This work was carried out by a project group within the GRADE Working Group, through brainstorming and iterative refinement of ideas, using input from workshops, presentations, and discussions at GRADE Working Group meetings to produce this document, which constitutes official GRADE guidance. Results: Certainty of evidence is best considered as the certainty that a true effect lies on one side of a specified threshold or within a chosen range. We define possible approaches for choosing threshold or range. For guidelines, what we call a fully contextualized approach requires simultaneously considering all critical outcomes and their relative value. Less-contextualized approaches, more appropriate for systematic reviews and health technology assessments, include using specified ranges of magnitude of effect, for example, ranges of what we might consider no effect, trivial, small, moderate, or large effects. Conclusion: It is desirable for systematic review authors, guideline panelists, and health technology assessors to specify the threshold or ranges they are using when rating the certainty in evidence. (C) 2017 The Authors. Published by Elsevier Inc.

    Ladda ner fulltext (pdf)
    FULLTEXT01
  • 12. Hultin, Margareta
    et al.
    Davidson, Thomas
    Gynther, Göran
    Helgesson, Gert
    Jemt, Torsten
    Lekholm, Ulf
    Nilner, Krister
    Malmö högskola, Odontologiska fakulteten (OD).
    Nordenram, Gunilla
    Norlund, Anders
    Sunnegårdh-Grönberg, Karin
    Tranæus, Sofia
    Oral Rehabilitation of Tooth Loss: A Systematic Review of Quantitative Studies of OHRQoL2012Ingår i: International Journal of Prosthodontics, ISSN 0893-2174, E-ISSN 1139-9791, Vol. 25, nr 6, s. 543-552Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Purpose: This study aimed to review published quantitative studies for evidence regarding the influence of oral rehabilitation following total or partial tooth loss on self-perceived oral health–related quality of life (OHRQoL). Materials and Methods: Three databases were searched using specified indexing terms. The reference lists of relevant publications were also searched manually. Quality of evidence was classified according to GRADE guidelines as high, moderate, low, or very low. Results: The search yielded 2,138 titles and abstracts, 2,102 of which were of a quantitative study design. Based on pre-established criteria, the full-text versions of 322 articles were obtained. After data extraction and interpretation, 5 publications of high or moderate study quality remained. The results of these 5 studies showed positive effects of oral rehabilitation on OHRQoL. Two studies showed substantial improvements. Conclusions: This is a relatively new field of research; there are very few quantitative studies of how patients perceive OHRQoL following tooth loss and subsequent rehabilitation. While this review indicates that treatment has positive effects on quality of life, the scientific basis is insufficient to support general conclusions about the influence of various interventions on the OHRQoL of patients who have experienced total or partial tooth loss. To achieve a more comprehensive analysis, it is recommended that future studies be based on a combination of quantitative and qualitative methods, ie, questionnaires and semi-structured interviews. The follow-up period must also be appropriate for the specific intervention studied.

  • 13.
    Häggman-Henrikson, Birgitta
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Alstergren, Per
    Malmö högskola, Odontologiska fakulteten (OD).
    Davidson, T
    Malmö högskola, Odontologiska fakulteten (OD).
    Högestätt, ED
    Östlund, Pernilla
    Department of Odontology/Clinical Oral Physiology, Umeå University, Umeå, Sweden; Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU), Stockholm, Sweden.
    Tranaeus, Sofia
    Vitols, S
    List, Thomas
    Malmö högskola, Odontologiska fakulteten (OD).
    Pharmacological treatment of oro-facial pain: health technology assessment including a systematic review with network meta-analysis.2017Ingår i: Journal of Oral Rehabilitation, E-ISSN 1365-2842, Vol. 44, nr 10, s. 800-826Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    This health technology assessment evaluated the efficacy of pharmacological treatment in patients with oro-facial pain. Randomised controlled trials were included if they reported pharmacological treatment in patients ≥18 years with chronic (≥3 months) oro-facial pain. Patients were divided into subgroups: TMD-muscle [temporomandibular disorders (TMD) mainly associated with myalgia]; TMD-joint (TMD mainly associated with temporomandibular joint pain); and burning mouth syndrome (BMS). The primary outcome was pain intensity reduction after pharmacological treatment. The scientific quality of the evidence was rated according to GRADE. An electronic search in PubMed, Cochrane Library, and EMBASE from database inception to 1 March 2017 combined with a handsearch identified 1552 articles. After screening of abstracts, 178 articles were reviewed in full text and 57 studies met the inclusion criteria. After risk of bias assessment, 41 articles remained: 15 studies on 790 patients classified as TMD-joint, nine on 375 patients classified as TMD-muscle and 17 on 868 patients with BMS. Of these, eight studies on TMD-muscle, and five on BMS were included in separate network meta-analysis. The narrative synthesis suggests that NSAIDs as well as corticosteroid and hyaluronate injections are effective treatments for TMD-joint pain. The network meta-analysis showed that clonazepam and capsaicin reduced pain intensity in BMS, and the muscle relaxant cyclobenzaprine, for the TMD-muscle group. In conclusion, based on a limited number of studies, evidence provided with network meta-analysis showed that clonazepam and capsaicin are effective in treatment of BMS and that the muscle relaxant cyclobenzaprine has a positive treatment effect for TMD-muscle pain.

  • 14.
    Johansson, Krister
    et al.
    Malmö universitet, Odontologiska fakulteten (OD).
    Götrick, Bengt
    Malmö universitet, Odontologiska fakulteten (OD).
    Holst, Jan
    Department of Vascular Diseases and HTA Syd, Skåne University Hospital, Malmö/Lund, Sweden.
    Tranæus, Sofia
    Malmö universitet, Odontologiska fakulteten (OD).
    Naimi-Akbar, Aron
    Malmö universitet, Odontologiska fakulteten (OD).
    Impact of direct oral anticoagulants on bleeding tendency and postoperative complications in oral surgery: a systematic review of controlled studies2023Ingår i: Oral surgery, oral medicine, oral pathology and oral radiology, ISSN 2212-4403, E-ISSN 2212-4411, Vol. 135, nr 3, s. 333-346, artikel-id S2212-4403(22)01047-1Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    OBJECTIVE: The recommendations for the management of direct oral anticoagulants (DOACs) in oral surgery are inconsistent. The present review evaluated whether DOACs increase the risk of bleeding during oral surgery and postoperative complications.

    STUDY DESIGN: The patients undergoing oral surgery and receiving a DOAC were compared with the patients receiving a DOAC different from the exposure, a vitamin K antagonist (VKA), or no anticoagulant. Three electronic databases were searched for eligible clinical trials and systematic reviews. The risk of bias was assessed, data were extracted, a meta-analysis was done, and the Grading of Recommendations, Assessment, Development and Evaluations certainty-of-evidence ratings were determined.

    RESULTS: Three clinical trials comparing patients receiving DOAC medication with patients on a VKA were eligible. A meta-analysis of bleeding 7 days postoperatively detected no significant differences between patients continuing DOAC or VKA medication during and after surgery. All of the point estimates favored uninterrupted DOAC over VKA therapy. Tranexamic acid was topically administered to some patients.

    CONCLUSIONS: Based on an interpreted trend among 3 studies with mixed patient populations, the risk of bleeding during the first 7 postoperative days may be lower for patients on uninterrupted DOAC than VKA therapy (⨁⨁⭘⭘), but the effect size of the risk is unclear. 80 of 274 included patients experienced postoperative bleeding.

    Ladda ner fulltext (pdf)
    fulltext
  • 15.
    Johansson, Krister
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Jimbo, Ryo
    Malmö högskola, Odontologiska fakulteten (OD).
    Östlund, Pernilla
    Malmö högskola, Odontologiska fakulteten (OD).
    Tranæus, Sofia
    Malmö högskola, Odontologiska fakulteten (OD). Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden.
    Becktor, Jonas P
    Malmö högskola, Odontologiska fakulteten (OD).
    Effects of Bacterial Contamination on Dental Implants During Surgery: A Systematic Review2017Ingår i: Implant Dentistry, ISSN 1056-6163, E-ISSN 1538-2982, Vol. 26, nr 5, s. 778-789Artikel, forskningsöversikt (Refereegranskat)
    Abstract [en]

    INTRODUCTION: Contamination during surgery negatively influences the prognosis of orthopaedic implants; however, it has not been proven whether contamination influences the success of dental implant treatment. The aim of the systematic review was to investigate if there exists evidence in the literature whether contamination of dental implants during surgery affects osseointegration and clinical success. MATERIALS AND METHODS: Four data bases were used for the literature search. Primary studies and reviews regarding both clinical and preclinical research were eligible. Rating of the summarized quality of the evidence was performed. RESULTS: Five preclinical studies were included. Because of the estimated high risk of bias in all included studies and extensive differences in study design between the included studies, meta-analysis was not performed and no reliable aggregated data could be extracted. CONCLUSIONS: It is suggested that the scientific evidence with regard to the current topic is insufficient. Further controlled studies are warranted.

  • 16.
    Kirkinen, Tita
    et al.
    Malmö universitet, Odontologiska fakulteten (OD). Clinic of Paediatric Dentistry, Region Värmland, Karlstad, Sweden.
    Naimi-Akbar, Aron
    Malmö universitet, Odontologiska fakulteten (OD).
    Cederlund, Andreas
    Forsknings- och utvecklingsavdelningen, Folktandvården Stockholms län AB, Stockholm, Sweden.
    Tranæus, Sofia
    Malmö universitet, Odontologiska fakulteten (OD). Faculty of OdonSBU Assesses and Knowledge gaps, Swedish Agency for Health Technology Assessment and Assessment of Social Services, Stockholm, Sweden.
    Carlson, Christina
    Department of Preventive Dentistry, Region Värmland, Karlstad, Sweden.
    Klingberg, Gunilla
    Malmö universitet, Odontologiska fakulteten (OD).
    Accuracy of the Swedish quality registry for caries and periodontal diseases (SKaPa) – evaluation in 6- and 12-year-olds in the region of Värmland, Sweden2023Ingår i: Acta Odontologica Scandinavica, ISSN 0001-6357, E-ISSN 1502-3850, Vol. 81, nr 8, s. 615-621Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objectives This study evaluates the agreement of data on dental caries between electronic dental records and data retrieved from the national SKaPa-registry (Swedish Quality Registry for caries and periodontal disease), with special reference to e/M in deft/DMFT.

    Methods In a random sample of 500 6- and 12-year-old children having received dental care in 2014 in the county region of Värmland, Sweden, the diagnostic accuracy of data in electronic dental records with corresponding data obtained from the SKaPa-registry was compared by using Cohen’s Kappa and Intraclass correlation coefficient (ICC).

    Results For dft/DFT the Kappa was 0.95, and ICC 0.98 (total population). For deft/DMFT in the total population the Kappa was 0.80 and ICC 0.96. For 6-year-olds (deft) the Kappa was 0.89 and ICC 0.99 and for 12-year-olds (DMFT) the Kappa was 0.70, and ICC 0.83. The corresponding figures for Kappa and ICC when excluding individuals without caries (deft/DMFT = 0) were: Total population 0.63 and 0.94; 6-year-olds 0.79 and 0.99; 12-year-olds 0.42 and 0.68.

    Conclusion Agreement between data in the dental records and SKaPa was very high for dft/DFT confirming that transfer from the dental records to the SKaPa-registry is safe and correct. As the accuracy of deft/DMFT was considerably lower than for dft/DFT we advise against using deft/DMFT data from SKaPa for research purposes at this point.

    Ladda ner fulltext (pdf)
    fulltext
  • 17.
    Klingberg, Gunilla
    et al.
    Malmö universitet, Odontologiska fakulteten (OD).
    Benchimol, Daniel
    Karolinska Institutet, Sweden.
    Berlin, Henrik
    Malmö universitet, Odontologiska fakulteten (OD).
    Bring, Johan
    Statisticon AB, Uppsala.
    Gornitzki, Carl
    Swedish Agency for Health Technology Assessment and Assessment of Social Services, Stockholm.
    Odeberg, Jenny
    Swedish Agency for Health Technology Assessment and Assessment of Social Services, Stockholm.
    Tranæus, Sofia
    Malmö universitet, Odontologiska fakulteten (OD). Swedish Agency for Health Technology Assessment and Assessment of Social Services, Stockholm.
    Twetman, Svante
    Department of Odontology, University of Copenhagen, Copenhagen, Denmark.
    Wernersson, Emma
    Swedish Agency for Health Technology Assessment and Assessment of Social Services, Stockholm.
    Östlund, Pernilla
    Malmö universitet, Odontologiska fakulteten (OD). Swedish Agency for Health Technology Assessment and Assessment of Social Services, Stockholm.
    Domeij, Helena
    Malmö universitet, Odontologiska fakulteten (OD). Swedish Agency for Health Technology Assessment and Assessment of Social Services, Stockholm.
    How old are you?: a systematic review investigating the relationship between age and mandibular third molar maturity2023Ingår i: PLOS ONE, E-ISSN 1932-6203, Vol. 18, nr 5, s. 1-14, artikel-id e0285252Artikel, forskningsöversikt (Refereegranskat)
    Abstract [en]

    Introduction and objective: Radiographic evaluation of the maturity of mandibular third molars is a common method used for age estimation of adolescents and young adults. The aim of this systematic review was to examine the scientific base for the relationship between a fully matured mandibular third molar based on Demirjian's method and chronological age, in order to assess whether an individual is above or below the age of 18 years.

    Methods: The literature search was conducted in six databases until February 2022 for studies reporting data evaluating the tooth maturity using Demirjian´s method (specifically stage H) within populations ranging from 8 to 30 years (chronological age). Two reviewers screened the titles and abstracts identified through the search strategy independently. All studies of potential relevance according to the inclusion criteria were obtained in full text, after which they were assessed for inclusion by two independent reviewers. Any disagreement was resolved by a discussion. Two reviewers independently evaluated the risk of bias using the assessment tool QUADAS-2 and extracted the data from the studies with low or moderate risk of bias. Logistic regression was used to estimate the relationship between chronological age and proportion of subjects with a fully matured mandibular third molar (Demirjian´s tooth stage H).

    Results: A total of 15 studies with low or moderate risk of bias were included in the review. The studies were conducted in 13 countries and the chronological age of the investigated participants ranged from 3 to 27 years and the number of participants ranged between 208 and 5,769. Ten of the studies presented the results as mean age per Demirjian´s tooth stage H, but only five studies showed the distribution of developmental stages according to validated age. The proportion of subjects with a mandibular tooth in Demirjian´s tooth stage H at 18 years ranged from 0% to 22% among males and 0 to 16% in females. Since the studies were too heterogenous to perform a meta-analysis or a meaningful narrative review, we decided to refrain from a GRADE assessment.

    Conclusion: The identified literature does not provide scientific evidence for the relationship between Demirjian´s stage H of a mandibular third molar and chronologic age in order to assess if an individual is under or above the age of 18 years.

    Ladda ner fulltext (pdf)
    fulltext
  • 18.
    Klinge, Anna
    et al.
    Malmö universitet, Odontologiska fakulteten (OD).
    Khalil, Dalia
    Klinge, Björn
    Malmö universitet, Odontologiska fakulteten (OD).
    Lund, Bodil
    Naimi-Akbar, Aron
    Malmö universitet, Odontologiska fakulteten (OD).
    Tranæus, Sofia
    Malmö universitet, Odontologiska fakulteten (OD).
    Hultin, Margareta
    Prophylactic antibiotics for staged bone augmentation in implant dentistry2020Ingår i: Acta Odontologica Scandinavica, ISSN 0001-6357, E-ISSN 1502-3850, Vol. 78, nr 1, s. 64-73Artikel, forskningsöversikt (Refereegranskat)
    Abstract [en]

    Background: The objective of the study was to assess the effect of prophylactic antibiotics on the outcome of bone augmentation and subsequent dental implant placement by combining the recommended quality assessment methods for systematic reviews and primary studies.

    Materials and methods: This is a complex systematic review in which systematic reviews as well as primary studies are scrutinised. A search of Medline (OVID), The Cochrane Library (Wiley) and EMBASE, PubMed and Health technology assessment (HTA) organisations as-well as a complementary hand-search was carried out. Selected primary studies were assessed using GRADE. Each study was reviewed by three authors independently.

    Results: Abstract screening yielded six potential systematic reviews allocated for full-text inspection. A total of ten primary studies were read in full-text. No relevant systematic reviews regarding the topic of this article were found. The quality assessment resulted in two primary studies with a moderate risk of bias. Of the two studies with a moderate risk of bias, one compared a single dose of clindamycin 600 mg preoperatively with the same preoperative dose followed by four doses of 300 mg every 6 h. The second study compared a single dose prophylaxis of two different types of antibiotic compounds.

    Conclusion: In conclusion, the scientific evidence regarding the use of antibiotic prophylaxis for reducing the risk of infection in conjunction with bone augmentation procedures during dental implant placement is very limited. The infection rate as compared to nonusage of prophylactic antibiotics, selection of the most suitable compound, and the optimal duration of prophylactic treatment is still unknown.

  • 19.
    Klinge, Anna
    et al.
    Malmö universitet, Odontologiska fakulteten (OD).
    Tranaeus, Sofia
    Malmö universitet, Odontologiska fakulteten (OD).
    Becktor, Jonas P
    Malmö universitet, Odontologiska fakulteten (OD).
    Winitsky, Nicole
    Naimi-Akbar, Aron
    Malmö universitet, Odontologiska fakulteten (OD).
    The risk for infraposition of dental implants and ankylosed teeth in the anterior maxilla related to craniofacial growth, a systematic review2021Ingår i: Acta Odontologica Scandinavica, ISSN 0001-6357, E-ISSN 1502-3850, Vol. 79, nr 1, s. 59-68Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background The aim of the study was to evaluate a potential association between individuals with different craniofacial types or other exposures, and the risk of infraposition due to continued growth/eruption of adjacent teeth in the anterior maxilla. Materials and methods This is a systematic review in which primary studies as well as other systematic reviews are scrutinised. A search of PubMed (Medline), Scopus, Web of science and Health technology assessment (HTA) organisations and a complementary handsearch was carried out. Selected studies were read in full-text by several reviewers. The quality of the included primary studies was assessed using a protocol for assessment of risk of bias in exposure studies. Results The literature search resulted in 3,296 publications. Title and abstract screening yielded 25, whereof one systematic review, potential publications allocated for full-text inspection. The quality assessment resulted in a total of seven studies with a low/moderate risk of bias and four studies with a high risk of bias. Conclusion In conclusion, a long-term risk for infraposition of dental implants, or ankylosed teeth, among natural teeth can be observed in some cases. The predisposing factors are still not fully understood since the current scientific evidence is very limited.

    Ladda ner fulltext (pdf)
    fulltext
  • 20. Lund, Bodil
    et al.
    Hultin, Margareta
    Tranæus, Sofia
    Malmö högskola, Odontologiska fakulteten (OD).
    Naimi-Akbar, Aran
    Klinge, Björn
    Malmö högskola, Odontologiska fakulteten (OD).
    Complex systematic review: Perioperative antibiotics in conjunction with dental implant placement2015Ingår i: Clinical Oral Implants Research, ISSN 0905-7161, E-ISSN 1600-0501, Vol. 26, nr Suppl 11, s. 1-14Artikel, forskningsöversikt (Refereegranskat)
    Abstract [en]

    OBJECTIVES: The aim of this study was to revisit the available scientific literature regarding perioperative antibiotics in conjunction with implant placement by combining the recommended methods for systematic reviews and complex systematic reviews. MATERIAL AND METHODS: A search of Medline (OVID), The Cochrane Library (Wiley), EMBASE, PubMed and Health technology assessment (HTA) organizations was performed, in addition to a complementary hand-search. Selected systematic reviews and primary studies were assessed using GRADE and AMSTAR, respectively. A meta-analysis was performed. RESULTS: The literature search identified 846 papers of which 10 primary studies and seven systematic reviews were included. Quality assessment of the systematic reviews revealed two studies of moderate risk of bias and five with high risk of bias. The two systematic reviews of moderate risk of bias stated divergent numbers needed to treat (NNT) to prevent one patient from implant failure. Four of the primary studies comparing antibiotic prophylaxis with placebo were estimated to be of low, or moderate, risk of bias and subjected to meta-analysis. The NNT was 50 (pooled RR 0.39, 95% CI 0.18, 0.84; P = 0.02). None of these four studies individually show a statistical significant benefit of antibiotic prophylaxis. Furthermore, narrative analysis of the studies eligible for meta-analysis reveals clinical heterogeneity regarding intervention and smoking. CONCLUSION: Antibiotic prophylaxis in conjunction with implant placement reduced the risk for implant loss by 2%. However, the sub-analysis of the primary studies suggests that there is no benefit of antibiotic prophylaxis in uncomplicated implant surgery in healthy patient.

  • 21.
    Mejàre, Ingegerd
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Axelsson, Susanna
    Davidson, Thomas
    Frisk, Fredrik
    Hakeberg, Magnus
    Kvist, Thomas
    Norlund, Aanders
    Petersson, Arne
    Malmö högskola, Odontologiska fakulteten (OD).
    Portenier, Isabelle
    Sandberg, Hans
    Tranæus, Sofia
    Bergenholtz, Gunnar
    Diagnosis of the condition of the dental pulp: a systematic review2012Ingår i: International Endodontic Journal, ISSN 0143-2885, E-ISSN 1365-2591, Vol. 45, nr 7, s. 597-613Artikel, forskningsöversikt (Refereegranskat)
    Abstract [en]

    The aim of this systematic review was to appraise the diagnostic accuracy of signs/symptoms and tests used to determine the condition of the pulp in teeth affected by deep caries, trauma or other types of injury. Radiographic methods were not included. The electronic literature search included the databases PubMed,EMBASE, The Cochrane Central Register of Controlled Trials and Cochrane Reviews from January 1950 to June 2011. The complete search strategy is given in an Appendix S1 (available online as Supporting Information. In addition, hand searches were made. Two reviewers independently assessed abstracts and full-text articles. An article was read in full text if at least one of the two reviewers considered an abstract to be potentially relevant. Altogether, 155 articles were read in full text. Of these, 18 studies fulfilled pre-specified inclusion criteria. The quality of included articles was assessed using the QUADAS tool. Based on studies of high or moderate quality, the quality of evidence of each diagnostic method/test was rated in four levels according to GRADE. No study reached high quality; two were of moderate quality. The overall evidence was insufficient to assess the value of toothache or abnormal reaction to heat/cold stimulation for determining the pulp condition. The same applies to methods for establishing pulp status, including electric or thermal pulp testing, or methods for measuring pulpal blood circulation. In general, there are major shortcomings in the design, conduct and reporting of studies in this domain of dental research.

  • 22. Mejàre, Ingegerd
    et al.
    Bergenholtz, G.
    Petersson, Kerstin
    Malmö högskola, Odontologiska fakulteten (OD).
    Tranæus, Sofia
    Estimates of sensitivity and specificity of electric pulp testing depend on pulp disease spectrum: a modelling study2015Ingår i: International Endodontic Journal, ISSN 0143-2885, E-ISSN 1365-2591, Vol. 48, nr 1, s. 74-78Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Aim To demonstrate how the spectrum of diseased pulps may influence sensitivity and specificity in diagnostic studies on pulp status. Methodology An original sample from a previous study consisting of 59 teeth scheduled for root canal treatment was used where the relationship between the response to electric pulp testing and the visual status of the pulp was evaluated. To alter the spectrum of diseased pulps, a hypothetical sample of asymptomatic teeth with deep caries lesions was added to the original sample. Sensitivity and specificity were then compared for the two samples. Results In the original sample of 59 teeth, sensitivity was 72% and specificity 90%. When the spectrum of diseased pulps was altered, sensitivity decreased to 67% and specificity increased to 97%. The change in disease spectrum also decreased the prevalence of necrotic pulps. Conclusions The spectrum of diseased pulps included in a diagnostic study on the accuracy of electric pulp testing, and indirectly also disease prevalence (here pulp necrosis), influences estimates of sensitivity and specificity. This implies that estimates of diagnostic accuracy from one study with a particular tooth population spectrum may not apply to another tooth population with a different disease spectrum.

  • 23. Mejàre, Ingegerd
    et al.
    Klingberg, Gunilla
    Malmö högskola, Odontologiska fakulteten (OD).
    Mowafi, Frida K
    Stecksén-Blicks, Christina
    Twetman, Svante H
    Tranæus, Sofia H
    A systematic map of systematic reviews in pediatric dentistry: what do we really know?2015Ingår i: PLOS ONE, E-ISSN 1932-6203, Vol. 10, nr 2, artikel-id e0117537Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    OBJECTIVES: To identify, appraise and summarize existing knowledge and knowledge gaps in practice-relevant questions in pediatric dentistry. METHODS: A systematic mapping of systematic reviews was undertaken for domains considered important in daily clinical practice. The literature search covered questions in the following domains: behavior management problems/dental anxiety; caries risk assessment and caries detection including radiographic technologies; prevention and non-operative treatment of caries in primary and young permanent teeth; operative treatment of caries in primary and young permanent teeth; prevention and treatment of periodontal disease; management of tooth developmental and mineralization disturbances; prevention and treatment of oral conditions in children with chronic diseases/developmental disturbances/obesity; diagnosis, prevention and treatment of dental erosion and tooth wear; treatment of traumatic injuries in primary and young permanent teeth and cost-effectiveness of these interventions. Abstracts and full text reviews were assessed independently by two reviewers and any differences were solved by consensus. AMSTAR was used to assess the risk of bias of each included systematic review. Reviews judged as having a low or moderate risk of bias were used to formulate existing knowledge and knowledge gaps. RESULTS: Out of 81 systematic reviews meeting the inclusion criteria, 38 were judged to have a low or moderate risk of bias. Half of them concerned caries prevention. The quality of evidence was high for a caries-preventive effect of daily use of fluoride toothpaste and moderate for fissure sealing with resin-based materials. For the rest the quality of evidence for the effects of interventions was low or very low. CONCLUSION: There is an urgent need for primary clinical research of good quality in most clinically-relevant domains in pediatric dentistry

    Ladda ner fulltext (pdf)
    FULLTEXT01
  • 24.
    Mensah, Tita
    et al.
    Malmö universitet, Odontologiska fakulteten (OD).
    Hjern, Anders
    Håkanson, Kickan
    Johansson, Pia
    Jonsson, Ann Kristine
    Mattsson, Titti
    Tranæus, Sofia
    Malmö universitet, Odontologiska fakulteten (OD).
    Vinnerljung, Bo
    Östlund, Pernilla
    Malmö universitet, Odontologiska fakulteten (OD).
    Klingberg, Gunilla
    Malmö universitet, Odontologiska fakulteten (OD).
    Organisational models of health services for children and adolescents in out-of-home care: health technology assessment2020Ingår i: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 109, nr 2, s. 250-257Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    AIM: Decades of research confirm that children and adolescents in out-of-home care (foster family, residential care) have much greater healthcare needs than their peers. A systematic literature review was conducted to evaluate organizational healthcare models for this vulnerable group. METHODS: A systematic literature search was undertaken of the following databases: Academic Search Elite, CENTRAL, Cochrane Database of Systematic Reviews, Cinahl, DARE, ERIC, HTA, PsycInfo, Psychology and Behavioural Sciences Collection, PubMed, SocIndex. Randomized and non-randomized controlled trials were to be included. Two pairs of reviewers independently assessed abstracts of the identified published papers. Abstracts meeting the inclusion criteria were ordered in full text. Each article was reviewed independently, by pairs of reviewers. A joint assessment was made based on the inclusion criteria and relevance. Cases of disagreement were resolved by consensus discussion. RESULTS: No study with low or medium risk of bias was identified. CONCLUSION: In the absence of studies of acceptable quality, it is not possible to assess the impact of organizational models intended to ensure adequate health and dental care for children and adolescents in out-of-home care. Therefore, well-designed follow-up studies should be conducted following the implementation of such models. This article is protected by copyright. All rights reserved.

    Ladda ner fulltext (pdf)
    FULLTEXT01
  • 25.
    Mensah, Tita
    et al.
    Malmö universitet, Odontologiska fakulteten (OD). Region Värmland.
    Tranæus, Sofia
    Malmö universitet, Odontologiska fakulteten (OD). Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU).
    Cederlund, Andreas
    Eastman Dental Institute, Stockholm.
    Naimi-Akbar, Aron
    Malmö universitet, Odontologiska fakulteten (OD).
    Klingberg, Gunilla
    Malmö universitet, Odontologiska fakulteten (OD).
    Swedish quality registry for caries and periodontal diseases (SKaPa): validation of data on dental caries in 6- and 12-year-old children2021Ingår i: BMC Oral Health, ISSN 1472-6831, E-ISSN 1472-6831, Vol. 21, artikel-id 373Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background

    The Swedish Quality Registry for caries and periodontal disease (SKaPa) automatically collects data on caries and periodontitis from patients’ electronic dental records. Provided the data entries are reliable and accurate, the registry has potential value as a data source for registry-based research. The aim of this study was to evaluate the reliability and accuracy of the SKaPa registry information on dental caries in 6- and 12-year-old children.

    Method

    This diagnostic accuracy study compared dental caries data registered at an examination with dental health status registered in the patient’s electronic dental records, and with corresponding data retrieved from the SKaPa registry. Clinical examinations of 170 6- and 12-year-old children were undertaken by one of the researchers in conjunction with the children’s regular annual dental examinations where the number of teeth were registered, and dental caries was diagnosed using ICDAS II. Teeth with fillings were defined as filled and were added to the ICDAS II score and subsequently dft/DFT was calculated for each individual. Cohen’s Kappa, the intraclass correlation coefficient (ICC), and sensitivity and specificity were calculated to test the agreement of the ‘decayed and filled teeth’ in deciduous and permanent teeth (dft/DFT) from the three sources.

    Results

    Cohen’s Kappa of the dft/DFT-values was calculated to 0.79 between the researcher and the patient record, to 0.95 between patient dental record and SKaPa, and to 0.76 between the researcher and SKaPa. Intraclass correlation coefficient (ICC) was calculated to 0.96 between the researcher and the patient journal, to 0.99 between the patient dental record vs. SKaPa, and to 0.95 between the researcher and SKaPa.

    Conclusion

    The SKaPa registry information demonstrated satisfactory reliability and accuracy on dental caries in 6- and 12-year-old children and is a reliable source for registry-based research.

    Ladda ner fulltext (pdf)
    fulltext
  • 26. Naimi-Akbar, Aron
    et al.
    Hultin, Margareta
    Klinge, Anna
    Malmö universitet, Odontologiska fakulteten (OD).
    Klinge, Björn
    Malmö universitet, Odontologiska fakulteten (OD).
    Tranæus, Sofia
    Malmö universitet, Odontologiska fakulteten (OD).
    Lund, Bodil
    Antibiotic prophylaxis in orthognathic surgery: A complex systematic review2018Ingår i: PLOS ONE, E-ISSN 1932-6203, Vol. 13, nr 1Artikel, forskningsöversikt (Refereegranskat)
    Abstract [en]

    Objective In orthognathic surgery, antibiotics are prescribed to reduce the risk of postoperative infection. However, there is lack of consensus over the appropriate drug, the dose and duration of administration. The aim of this complex systematic review was to assess the effect of antibiotics on postoperative infections in orthognathic surgery. Methods Both systematic reviews and primary studies were assessed. Medline (OVID), The Cochrane Library (Wiley) and EMBASE (embase.com), PubMed (non-indexed articles) and Health Technology Assessment (HTA) publications were searched. The primary studies were assessed using GRADE and the systematic reviews by AMSTAR. Results Screening of abstracts yielded 6 systematic reviews and 36 primary studies warranting full text scrutiny. In total, 14 primary studies were assessed for risk of bias. Assessment of the included systematic reviews identified two studies with a moderate risk of bias, due to inclusion in the meta-analyses of primary studies with a high risk of bias. Quality assessment of the primary studies disclosed one with a moderate risk of bias and one with a low risk. The former compared a single dose of antibiotic with 24 hour prophylaxis using the same antibiotic; the latter compared oral and intravenous administration of antibiotics. Given the limited number of acceptable studies, no statistical analysis was undertaken, as it was unlikely to contribute any relevant information. Conclusion With respect to antibiotic prophylaxis in orthognathic surgery, most of the studies to date have been poorly conducted and reported. Thus scientific uncertainty remains as to the preferred antibiotic and the optimal duration of administration.

    Ladda ner fulltext (pdf)
    FULLTEXT01
  • 27. Nordenram, Gunilla
    et al.
    Davidson, Thomas
    Gynther, Göran
    Helgesson, Gert
    Hultin, Margareta
    Jemt, Torsten
    Lekholm, Ulf
    Nilner, Krister
    Malmö högskola, Odontologiska fakulteten (OD).
    Norlund, Anders
    Rohlin, Madeleine
    Malmö högskola, Odontologiska fakulteten (OD).
    Sunnegårdh-Grönberg, Karin
    Tranæus, Sofia
    Malmö högskola, Odontologiska fakulteten (OD).
    Qualitative studies of patients' perceptions of loss of teeth, the edentulous state and prosthetic rehabilitation: A systematic review with meta-synthesis2013Ingår i: Acta Odontologica Scandinavica, ISSN 0001-6357, E-ISSN 1502-3850, Vol. 71, nr 3-4, s. 937-951Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objective. To conduct a systematic review and meta-synthesis of qualitative studies addressing patients' perceptions of loss of teeth, edentulism and oral rehabilitation. Background. Qualitative studies can complement quantitative studies by achieving deep understanding of patients' subjective experiences of losing teeth and coping with edentulism. They can also explore the perception that the benefits of prosthetic rehabilitation extend far beyond primary clinical treatment goals of restoration of oral function. Materials and methods. The major data bases were searched extensively for relevant qualitative and quantitative studies, followed by manual searching of the reference lists of included publications. Two authors independently read all abstracts. Relevant papers were retrieved in full-text and included or excluded according to a specially designed protocol. The included articles were then appraised and rated for quality: high, moderate or low. Articles of low quality were excluded. Results. The database search yielded 36 abstracts of qualitative studies; manual search disclosed one further article. All were read in full-text by two independent authors: 28 were excluded. Of the remaining nine, two (assessed as of low quality) were excluded for further analysis. Meta-synthesis, based on seven studies, disclosed two major themes: loss of quality-of-life associated with losing teeth and restored quality-of-life after oral rehabilitation. Conclusions. In this relatively new field of research, there are few published papers. Nevertheless, the studies to date show that loss of teeth is associated not only with compromised oral function, but also loss of social status and diminished self-esteem. Oral rehabilitation has broad positive implications, restoring quality of life and self-worth.

  • 28. Norlund, Anders
    et al.
    Axelsson, Susanna
    Dahlen, Gunnar
    Espelid, Ivar
    Mejàre, Ingegerd
    Malmö högskola, Odontologiska fakulteten (OD).
    Tranæus, Sofia
    Twetman, Svante
    Economic aspects of the detection of occlusal dentine caries2009Ingår i: Acta Odontologica Scandinavica, ISSN 0001-6357, E-ISSN 1502-3850, Vol. 67, nr 1, s. 38-43Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Swedish Council on Technology Assessment int Health Care, Stockholm, Sweden. OBJECTIVE: To evaluate the cost of true-positive occlusal dentine caries detection in permanent molars assessed by: (I) visual-tactile examination, (II) visual-tactile examination combined with bitewing radiographs, and (III) selective radiographic examination of patients with lesions detected clinically. A second aim was to analyse the different strategies when the costs of the subsequent restorative care are considered. METHODS: A model analysis was applied owing to the lack of original articles. Sensitivity and specificity were calculated from a systematic review and included in vitro and in vivo studies of medium and high quality. The direct costs for examinations and restorative care were extracted from the costs of the Public Dental Service in Sweden (2006). RESULTS: The diagnostic costs per true-positive finding were dependent on the occurrence of occlusal caries and increased with decreasing prevalence. The strategy by which radiographs were exposed selectively on the basis of findings from visual-tactile examination resulted in higher initial costs compared with the first and second strategies. When the costs of the subsequent restorative care were added, the selective strategy was most beneficial by up to 26% savings per true-positive diagnosis. However, with this selective strategy, more cases of true-positive dentine caries were assumed would remain undetected as compared with the combined strategy with visual-tactile examination and radiographs for all. CONCLUSIONS: The cost for a true-positive caries diagnosis was inversely related to caries occurrence, and different diagnostic strategies may display contrasting outcomes when subsequent restorative care is taken into account.

  • 29.
    Petersson, Arne
    et al.
    Malmö högskola, Odontologiska fakulteten (OD).
    Axelsson, Susanna
    Malmö högskola, Odontologiska fakulteten (OD).
    Davidson, Thomas
    Frisk, Fredrik
    Hakeberg, Magnus
    Kvist, Thomas
    Norlund, Anders
    Mejàre, Ingegerd
    Malmö högskola, Odontologiska fakulteten (OD).
    Portenier, Isabelle
    Sandberg, Hans
    Tranæus, Sofia
    Bergenholtz, Gunnar
    Radiological diagnosis of periapical bone tissue lesions in endodontics: a systematic review2012Ingår i: International Endodontic Journal, ISSN 0143-2885, E-ISSN 1365-2591, Vol. 45, nr 9, s. 783-801Artikel, forskningsöversikt (Refereegranskat)
    Abstract [en]

    This systematic review evaluates the diagnostic accuracy of radiographic methods employed to indicate presence/absence and changes over time of periapical bone lesions. Also investigated were the leads radiographic images may give about the nature of the process and the condition of the pulp in nonendodontically treated teeth. Electronic literature search included the databases PubMed, Embase and CENTRAL from January 1950 to June 2011. All languages were accepted provided there was an abstract in English. The MeSH terms were ‘Cone beam computed tomography (CBCT)’,‘Radiography, panoramic’, ‘Periapical diseases’, ‘Dental pulp diseases’, ‘Sensitivity and specificity’, ‘receiver operating characteristics (ROC) curve’, ‘Cadaver’, ‘Endodontics’ and ‘Radiography dental’. Two reviewers independently assessed abstracts and full text articles. An article was read in full text if at least one of the two reviewers considered an abstract to be potentially relevant. Altogether, 181 articles were read in full text. The GRADE approach was used to assess the quality of evidence of each radiographic method based on studies of high or moderate quality. Twenty-six studies fulfilled criteria set for inclusion. None was of high quality;11 were of moderate quality. There is insufficient evidence that the digital intraoral radiographic technique is diagnostically as accurate as the conventional film technique. The same applies to CBCT. No conclusions can be drawn regarding the accuracy of radiological examination in identifying various forms of periapical bone tissue changes or about the pulpal condition.

  • 30. Ástvaldsdóttir, Álfheidõur
    et al.
    Dagerhamn, Jessica
    van Dijken, Jan W. V.
    Naimi-Akbar, Aron
    Sandborgh-Englund, Gunilla
    Tranæus, Sofia
    Malmö högskola, Odontologiska fakulteten (OD).
    Nilsson, Mikael
    Malmö högskola, Odontologiska fakulteten (OD).
    Longevity of posterior resin composite restorations in adults: a systematic review2015Ingår i: Journal of Dentistry, ISSN 0300-5712, E-ISSN 1879-176X, Vol. 43, nr 8, s. 934-954Artikel, forskningsöversikt (Refereegranskat)
    Abstract [en]

    Objective: To conduct a systematic review of the literature on the longevity of posterior resin composite restorations in adults. Material and methods: A systematic literature search was conducted according to predetermined criteria for inclusion and exclusion. The studies selected were prospective clinical trials with a minimum follow-up time of 4 years, 40 restorations per experimental group and an annual attrition rate of less than 5%. Initially, abstracts and full-text articles were assessed independently and the assessment was subsequently agreed on by five reviewers. The methodological quality of the studies was assessed according to the Swedish Council on Health Technology Assessment (SBU) standard checklist for determining the extent to which studies meet basic quality criteria. Results: In all, the literature search identified 4275 abstracts and 93 articles were read in fulltext. There were eighteen studies which met the criteria for inclusion, eight of which were included in the analysis. There were 80 failures of restorations with a total follow-up time at risk for failure of 62,030 months. The overall incidence rate for all causes of failure was 1.55 lost restorations per 100 restoration years. The most common biological reason for failure (a total of 31 restorations) was secondary caries, with or without fracture of the restoration. The quality of the evidence was low. Conclusions: In an efficacy setting, the overall survival proportion of posterior resin composite restorations is high. The major reasons for failure are secondary caries and restoration fracture which supports the importance of adequate follow-up time. Clinical significance: The overall survival proportion of posterior composite restorations was high, but the results cannot be extrapolated to an effectiveness setting. The importance of adequate follow-up time is supported by the finding that secondary caries often occurred after 3 years or later. (C) 2015 Elsevier Ltd. All rights reserved.

  • 31. Ástvaldsdóttir, Álfheiður
    et al.
    Boström, Anne-Marie
    Davidson, Thomas
    Malmö universitet, Odontologiska fakulteten (OD).
    Gabre, Pia
    Gahnberg, Lars
    Sandborgh Englund, Gunilla
    Skott, Pia
    Ståhlnacke, Katri
    Tranæus, Sofia
    Malmö universitet, Odontologiska fakulteten (OD).
    Wilhelmsson, Hanna
    Malmö universitet, Malmö universitetsbibliotek.
    Wårdh, Inger
    Östlund, Pernilla
    Malmö universitet, Odontologiska fakulteten (OD).
    Nilsson, Mikael
    Malmö universitet, Odontologiska fakulteten (OD).
    Oral health and dental care of older persons: a systematic map of systematic reviews2018Ingår i: Gerodontology, ISSN 0734-0664, E-ISSN 1741-2358, nr 4, s. 290-304Artikel, forskningsöversikt (Refereegranskat)
    Abstract [en]

    OBJECTIVES: To examine the current knowledge on oral health status and dental care of older persons through a systematic mapping of systematic reviews of low or moderate risk of bias. BACKGROUND: Geriatric dentistry covers all aspects of oral health and oral care of older persons. Oral health is part of general health and contributes to a person's physical, psychological and social wellbeing. METHODS: A literature search was performed in three different databases (PubMed, The Cochrane Library and Cinahl) within 12 domains: Dental caries, periodontitis, Orofacial pain and temporomandibular joint (TMJ) pain, mucosal lesions, oral motor function, dry mouth, halitosis, interaction between oral status and other medical conditions, ability to interrelate and communicate, quality of life, ethics and organisation of dental care for older persons. Systematic reviews were identified and scrutinised, highlighting scientific knowledge and knowledge gaps. RESULTS: We included 32 systematic reviews of which 14 were judged to be of low/moderate risk of bias. Most of the domains lack systematic reviews with low or moderate risk of bias. In two of the domains evidence was identified; in institutionalised people aged 65 or older, effective oral hygiene can prevent pneumonia. Furthermore, there is an evidence of a relationship between malnutrition (protein energy-related malnutrition, PEM) and poor appetite and edentulousness. CONCLUSIONS: There is an urgent need for further research and evidence-based knowledge within most domains in geriatric dentistry and in other fields related to oral health and dental care for older persons striving for multi-disciplinary research programmes.

  • 32. Österberg, Marie
    et al.
    Holmlund, Anders
    Sunzel, Bo
    Department of Oral and Maxillofacial Surgery,Skanes University Hospital.
    Tranæus, Sofia
    Malmö högskola, Odontologiska fakulteten (OD).
    Twetman, Svante
    Lund, Bodil
    Knowledge Gaps in Oral and Maxillofacial Surgery: a Systematic Mapping2017Ingår i: International Journal of Technology Assessment in Health Care, ISSN 0266-4623, E-ISSN 1471-6348, Vol. 33, nr 1, s. 93-102Artikel, forskningsöversikt (Refereegranskat)
    Abstract [en]

    Objectives: The aim of this study was to evaluate available knowledge and identify knowledge gaps within the field of oral and maxillofacial surgery, by systematically collecting and evaluating systematic reviews. Twelve specific domains were selected: surgical removal of teeth, antibiotic and corticosteroid prophylaxis, orofacial infections, dental and facial trauma, orthognathic surgery, reconstructive surgery, benign tumors, cysts, premalignant lesions, oral complications of treatment of malignant tumors, hyperbaric oxygen therapy, temporomandibular joint surgery, cost effectiveness of different surgical treatments, and ethics. Methods: The literature search, covering four databases, was conducted during September 2014: PubMed, The Cochrane library, Centre for Reviews and Dissemination and EBSCO dentistry and oral science source. Retrieved systematic reviews were quality assessed by AMSTAR. Results: In all, 1,778 abstracts were identified, of which 200 met the inclusion criteria. Forty-five systematic reviews were assessed as of high to moderate quality. The results disclosed some existing evidence in a few domains, such as surgical removal of teeth and implant survival after sinus lifts. However, in all domains, the search revealed a large number of knowledge gaps. Also of concern was the lack of data regarding health economics and ethics. Conclusions: In conclusion, there is a need for well-conducted clinical research in the fields of oral and maxillofacial surgery.

1 - 32 av 32
RefereraExporteraLänk till träfflistan
Permanent länk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf