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5-y follow-up study of patients with neuroborreliosis
Lund University / Blekinge Institute of Technology / Research Centre for Zoonotic Ecology and Epidemiology.
Lund University / Blekinge Institute of Technology.ORCID iD: 0000-0002-8673-5109
Lund University.
Båstad Health Center.
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2002 (English)In: Scandinavian Journal of Infectious Diseases, ISSN 0036-5548, E-ISSN 1651-1980, Vol. 34, no 6, p. 421-425Article in journal (Refereed) Published
Abstract [en]

The objective of this follow-up study was to determine the long-term outcome of strictly classified cases of neuroborreliosis treated with antibiotics. A one-year prospective population-based survey of Lyme borreliosis was conducted in southern Sweden, between 1992 and 1993. A total of 349 identified cases with suspected neuroborreliosis were followed up 5 years later. Medical records were reviewed and all participants filled in a questionnaire. Of those classified with definite neuroborreliosis 114/130 completed the follow-up, of whom 111 had completed the initial antibiotic treatment. Of the 114 patients followed up, 86 (75%) had recovered completely and 70 (61%) had recovered within 6 months. Residual neurological symptoms such as facial palsy, concentration disorder, paresthesia and/or neuropathy were reported by 28/114. No significant differences between different antibiotic treatments were observed in terms of occurrence of sequelae. To conclude, we found that 25% (95% confidence interval 17-33%) of the patients suffered from residual neurological symptoms 5 years post-treatment. However, the clinical outcome of treated neuroborreliosis is favourable as only 14/114 (12%) of the patients had sequelae that influenced their daily activity post-treatment. Early diagnosis and treatment would seem to be of great importance in order to avoid such sequelae.

Place, publisher, year, edition, pages
2002. Vol. 34, no 6, p. 421-425
Keywords [en]
neuroborreliosis, ticks follow-up
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
URN: urn:nbn:se:mau:diva-63900DOI: 10.1080/00365540110080421ISI: 000177058300005PubMedID: 12160168Scopus ID: 2-s2.0-0035990579OAI: oai:DiVA.org:mau-63900DiVA, id: diva2:1814859
Available from: 2023-11-27 Created: 2023-11-27 Last updated: 2023-11-27Bibliographically approved

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Stjernberg, Louise

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