The use of open standards to promote responsible and available design in Internet-based healthcare systems is examined by using theoretical notations and recent research results from the literature. Moreover, empirical data will be gathered from a case study on an e-healthcare system for depression treatment. Our contribution is to initiate a discussion aiming at increasing the awareness on appropriate conceptual models for Internet-based depression treatment. Moreover, an up-to-date e-healthcare system, based on open standards and implemented with requirements of an Internet-based system treating patients suffering from depressions, is proposed.