While botnets still pose a big threat, they have also developed to be the most dangerous dark applications over the web. They are able to compromise a multitude of computers under the Command and Control (C&C) infrastructure, that is mainly controlled by a botherder/botmaster. Normally, a botnet uses malicious code to achieve its objectives and usually the motivation is based on either financial gain or Denial of Service (DoS) attack. The problem that is being addressed in this paper is structured to explore how a botnet's C&C infrastructure can be taken down based on how the botnet propagates itself within a network. The authors have used Zeus Botnet (ZBot) propagation model as a basis for this study. The main objective is to identify ZBot propagation patterns in order to be able to propose the take down approaches of the C&C infrastructure which acts as botnet control point. It is imperative to note that, even though ZBot was mainly resilient to attacks because of its Peer-to-Peer (P2P) nature, still other Zeus variants were controlled or acted as centralized bots. The study is more inclined to exploring the centralized Zeus variants like GameOver Zeus (GOZ) and ICE-IX for purposes of identifying the approaches. Based on the ZBot attack study, the C&C infrastructure can effectively be infiltrated hence averting unwarranted botnet attacks.