This chapter introduces the notion of design for learning sciences that broaden the idea of design in research. Inspired by the different design processes the differences of scientific and design problems and the role of design as a membrane between research and practice, a condensed process can be developed to bridge design-based research (DBR) and interaction design. One of things that differentiates designing for learning and other design activities are the learners. An important way of thinking about learning is learner-centered design (LCD). The chapter then examines design challenges and dilemmas across different research projects and offers insights on how to address them. Next, it looks at different design research and methods that can be applied to research projects. The chapter ends with a discussion on how to proceed in the design of learning sciences.