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Chitosan Nanoparticles Affect the Acid Tolerance Response in Adhered Cells of Streptococcus mutans
Malmö högskola, Faculty of Odontology (OD).
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2011 (English)In: Caries Research, ISSN 0008-6568, E-ISSN 1421-976X, Vol. 45, no 6, p. 501-505Article in journal (Refereed)
Abstract [en]

In this study we evaluated the effect of chitosan nanoparticles on the acid tolerance response (ATR) of adhered Streptococcus mutans. An ATR was induced by exposing S. mutans to pH 5.5 for 2 h and confirmed by exposing the acid-adapted cells to pH 3.5 for 30 min, with the majority of cells appearing viable according to the LIVE/DEAD® technique. However, when chitosan nanoparticles were present during the exposure to pH 5.5, no ATR occurred as most cells appeared dead after the pH 3.5 shock. We conclude that the chitosan nanoparticles tested had the ability to hinder ATR induction in adhered S. mutans.

Place, publisher, year, edition, pages
S. Karger, 2011. Vol. 45, no 6, p. 501-505
Keywords [en]
Acid tolerance, Biofilms, Chitosan, Nanoparticles, Streptococcus mutans
National Category
Dentistry
Identifiers
URN: urn:nbn:se:mau:diva-6344DOI: 10.1159/000331206ISI: 000298485900001PubMedID: 21912130Scopus ID: 2-s2.0-80052592962Local ID: 12957OAI: oai:DiVA.org:mau-6344DiVA, id: diva2:1403286
Available from: 2020-02-28 Created: 2020-02-28 Last updated: 2024-02-05Bibliographically approved

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Neilands, Jessica

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