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Nonlamellar lipid liquid crystalline model surfaces for biofunctional studies
Malmö högskola, Faculty of Health and Society (HS), Department of Biomedical Science (BMV).
2013 (English)In: Soft Matter, ISSN 1744-683X, E-ISSN 1744-6848, Vol. 9, no 37, p. 8815-8819Article in journal (Refereed)
Abstract [en]

Nonlamellar lipid liquid crystalline (LC) bulk phases and dispersions show promise as functional nanostructured materials for potential use as controlled release matrices e. g. in pharmaceuticals. Herein, methods for preparing and characterizing thin films of lipid liquid crystalline phases on solid surfaces are presented. The thickness, hydration phase structure and surface topography of spin-coated films of mixtures of soy phosphatidylcholine and glycerol dioleate are characterized by means of spectroscopic ellipsometry, small angle X-ray diffraction and atomic force microscopy. Besides being useful as bioadhesive drug delivery systems, the lipid nonlamellar LC films produced may also be exploited as model surfaces for studying properties such as bioadhesion and biodegradation.

Place, publisher, year, edition, pages
Royal Society of Chemistry, 2013. Vol. 9, no 37, p. 8815-8819
Keywords [en]
CUBIC PHASE, NANOPARTICLES, FILMS, PHOSPHATIDYLCHOLINE, MEMBRANES, MICELLES, BILAYERS, LIPIDS
National Category
Natural Sciences
Identifiers
URN: urn:nbn:se:mau:diva-4526DOI: 10.1039/c3sm51385hISI: 000323844600003Scopus ID: 2-s2.0-84883317929Local ID: 16451OAI: oai:DiVA.org:mau-4526DiVA, id: diva2:1401357
Available from: 2020-02-28 Created: 2020-02-28 Last updated: 2024-02-05Bibliographically approved

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Barauskas, Justas

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