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The stratum corneum barrier - From molecular scale to macroscopic properties
Lund Univ, Div Phys Chem, POB 124, S-22100 Lund, Sweden..
Malmö University, Faculty of Health and Society (HS), Department of Biomedical Science (BMV). Malmö University, Biofilms Research Center for Biointerfaces.ORCID iD: 0000-0001-6254-8539
Lund Univ, Div Phys Chem, POB 124, S-22100 Lund, Sweden.;Gillette Reading Innovat Ctr, Reading RG2 0QE, Berks, England..
Lund Univ, Div Phys Chem, POB 124, S-22100 Lund, Sweden.;CR Competence AB, Box 124, S-22100 Lund, Sweden..
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2023 (English)In: Current Opinion in Colloid & Interface Science, ISSN 1359-0294, E-ISSN 1879-0399, Vol. 67, article id 101725Article, review/survey (Refereed) Published
Abstract [en]

The upper layer of our skin, the stratum corneum (SC), is a versatile material that combines mechanical strength with efficient barrier function. In this paper, we discuss these macroscopic properties of SC in relation to recent findings on molecular responses and structural diversity in SC protein and lipids. We put particular focus on the intermediate (colloidal) length scale and how the different SC substructures are organized with respect to each other, including effects of nonequilibrium conditions in the skin with respect to the gradients in water and other components.

Place, publisher, year, edition, pages
Elsevier, 2023. Vol. 67, article id 101725
Keywords [en]
Fluid and solid lipids, Keratin filaments, Transport routes, Heterogenous, structures, Skin hydration
National Category
Physical Chemistry
Identifiers
URN: urn:nbn:se:mau:diva-63088DOI: 10.1016/j.cocis.2023.101725ISI: 001059987600001Scopus ID: 2-s2.0-85167567586OAI: oai:DiVA.org:mau-63088DiVA, id: diva2:1804163
Available from: 2023-10-11 Created: 2023-10-11 Last updated: 2023-10-11Bibliographically approved

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Björklund, Sebastian

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