Ett lyckat resultat av en endodontisk behandling är starkt förknippat med väl utförda behandlingsmoment, från att arbeta aseptiskt till den slutliga permanenta restaureringen. 

A successful outcome of endodontic treatment is strongly associated with well-performed treatment procedures. A prerequisite for satisfactory treatment is access to the root canals via an adequate access cavity preparation that is correctly positioned, of suitable size, and with straight-line access to the canals. After gaining access to the root canals the root canal working length is determined by an electronic apex locator combined with radiographs, preferably after coronal flaring. The root canals are then cleaned and shaped, and in most cases rotary or reciprocating nickel-titanium instruments can be used. This is performed in conjunction with the use of an irrigation solution, usually a low concentration of sodium hypochlorite. Once the chemo-mechanical instrumentation has been thoroughly performed, filling of the root canals is the next essential step. A good quality root filling should end within 2 mm from the radiographic apex without any voids. This is of significant importance for a successful outcome of the treatment, while the materials and techniques appear less important. Lastly, the tooth should be permanently restored as soon as possible after the root filling, to prevent fracture and reinfection.

Provided that the treatment procedures have been adequately performed, under aseptic conditions,  high success rates can be expected.