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Developing and evaluating non-invasive healthcare technologies for a group of female participants from a socioeconomically disadvantaged area
Malmö University, Faculty of Health and Society (HS), Department of Biomedical Science (BMV).
Malmö University, Faculty of Health and Society (HS), Department of Care Science (VV).ORCID iD: 0000-0003-4603-9974
Malmö University, Faculty of Health and Society (HS), Department of Biomedical Science (BMV).
Malmö University, Faculty of Health and Society (HS), Department of Care Science (VV).ORCID iD: 0000-0003-1235-620X
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2021 (English)In: Scientific Reports, E-ISSN 2045-2322, Vol. 11, no 1, article id 23896Article in journal (Refereed) Published
Abstract [en]

When compared to the general population, socioeconomically disadvantaged communitiesfrequently experience compromised health. Monitoring the divide is challenging since standardizedbiomedical tests are linguistically and culturally inappropriate. The aim of this study was to developand test a unique mobile biomedical testbed based on non-invasive analysis, as well as to explorethe relationships between the objective health measures and subjective health outcomes, asevaluated with the World Health Organization Quality of Life survey. The testbed was evaluated in asocioeconomically disadvantaged neighborhood in Malmö, which has been listed as one of the twelvemost vulnerable districts in Sweden. The study revealed that compared to conventional protocolsthe less intrusive biomedical approach was highly appreciated by the participants. Surprisingly, thecollected biomedical data illustrated that the apparent health of the participants from the ethnicallydiverse low-income neighborhood was comparable to the general Swedish population. Statisticallysignificant correlations between perceived health and biomedical data were disclosed, even thoughthe dependences found were complex, and recognition of the manifest complexity needs to beincluded in further research. Our results validate the potential of non-invasive technologies incombination with advanced statistical analysis, especially when combined with linguistically andculturally appropriate healthcare methodologies, allowing participants to appreciate the significanceof the different parameters to evaluate and monitor aspects of health.

Place, publisher, year, edition, pages
Nature Publishing Group, 2021. Vol. 11, no 1, article id 23896
National Category
Health Care Service and Management, Health Policy and Services and Health Economy
Identifiers
URN: urn:nbn:se:mau:diva-48214DOI: 10.1038/s41598-021-03262-3ISI: 000729935300085PubMedID: 34903797Scopus ID: 2-s2.0-85121044920OAI: oai:DiVA.org:mau-48214DiVA, id: diva2:1620817
Funder
Malmö University, FO 4.3-218/408Malmö University, FO 2020/299Malmö University, FO 2020/299Vinnova, 2017–01272Vinnova, 2016–00421Available from: 2021-12-16 Created: 2021-12-16 Last updated: 2024-02-26Bibliographically approved
In thesis
1. Non-invasive biomedical analysis: recent advances, challenges, and future perspectives
Open this publication in new window or tab >>Non-invasive biomedical analysis: recent advances, challenges, and future perspectives
2024 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Non-invasive healthcare technologies are increasingly pivotal in research anddevelopment due to their affordability and the convenience they offer to bothhealthcare recipients and providers. Alongside traditional non-invasive methodssuch as ultrasound imaging, a variety of innovative non-invasive devices havebeen developed. These include cardiovascular diagnostic systems, bioimpedancebasedscales, and various types of analyzers. These analyzers, which can be fluidlessor fluid-based, are capable of measuring not just physical parameters of thebody but also key biomarkers like glucose and lactate. This comprehensive andtransdisciplinary thesis encompasses three distinct yet interconnected segments:1) Advanced ultrasound imaging (Papers I and II): The first explored vortexformation time in female athletes and the second detailed investigations of thesuperficial venous systems of apparently healthy volunteers.2) Validation and application of commercially available fluid-less bloodanalyzers (Papers IV-VI). These papers focus on non-invasive blood glucosemonitoring (Paper IV) and the general use of non-invasive healthcaretechnologies among female participants from socioeconomicallydisadvantaged areas (Papers V and VI).3) Design and testing of novel, fluid-based sensors, and biosensors (Papers II andIII): Paper II delves into biosensing of viruses, and paper III deals withcontinuous ex vivo glucose sensing in human blood using an enzymatic sensorin a vein replica.Each of these segments contribute to the broader understanding and advancementof non-invasive healthcare technologies, highlighting the significant role suchtechnologies play in modern healthcare research. The thesis's transdisciplinaryapproach, spanning from advanced imaging techniques to the development ofnovel biosensors, exemplifies the dynamic and evolving nature of medicaltechnology research.

Place, publisher, year, edition, pages
Malmö: Malmö University Press, 2024. p. 64
Series
Malmö University Health and Society Dissertations, ISSN 1653-5383
National Category
Medical and Health Sciences
Research subject
Health and society
Identifiers
urn:nbn:se:mau:diva-66097 (URN)10.24834/isbn.9789178774562 (DOI)978-91-7877-455-5 (ISBN)978-91-7877-456-2 (ISBN)
Public defence
2024-03-01, Aula, Health, and Society, Jan Waldenströms gata 25, 205 06, Malmö, 13:00 (English)
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Supervisors
Note

Paper IV in dissertation as manuscript

Available from: 2024-02-27 Created: 2024-02-26 Last updated: 2024-03-18Bibliographically approved

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Awad, EmanRamji, RathiCirovic, StefanRämgård, MargaretaKottorp, AndersShleev, Sergey

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