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Enzyme encapsulation in nanostructured self-assembled structures: Toward biofunctional supramolecular assemblies
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2019 (English)In: Current Opinion in Colloid & Interface Science, ISSN 1359-0294, E-ISSN 1879-0399, Vol. 44, p. 130-142Article, review/survey (Refereed) Published
Abstract [en]

Enzymes have come into use for many new applications outside their natural biological environment, taking advantage of their high efficiency and selectivity as biocatalysts. Such new application often requires encapsulation to preserve the structure and activity of the enzyme, but also to regulate and control the activity. Here, we will discuss two types of encapsulation, soft matrices consisting of polar lipid liquid crystals and hard ordered mesoporous silica matrices. For both types of matrices, the challenge is to control the pore size of the matrices and the interaction with the matrix interface. Here, the polar lipid liquid crystals offer larger flexibility than silica, but on the other hand, it is considerably more sensitive to the environment.

Place, publisher, year, edition, pages
Elsevier, 2019. Vol. 44, p. 130-142
Keywords [en]
Enzyme encapsulation, Enzyme activity, Pore size, Polar lipid liquid crystals, Cubic phase, Mesoporous silica
National Category
Physical Chemistry
Identifiers
URN: urn:nbn:se:mau:diva-17256DOI: 10.1016/j.cocis.2019.09.007ISI: 000506474700011Scopus ID: 2-s2.0-85074691860OAI: oai:DiVA.org:mau-17256DiVA, id: diva2:1430057
Available from: 2020-05-13 Created: 2020-05-13 Last updated: 2024-02-05Bibliographically approved

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Salis, AndreaBarauskas, JustasArnebrant, Thomas

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