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Title [sv]
On Failure and success of oral implants
Title [en]
On Failure and success of oral implants
Abstract [sv]

Hur går studien till,
Projektet inkluderar analys av faktorer som kan kopplas till komplikationer och förlust av implantat. Experimentella försök används för att förklara olika kliniska fynd.

Abstract [en]

The aim of the present investigation is to analyze the reasons for peri-implantitis in animal models and couple these findings to results from retrospective and prospective clinical studies of oral implants. The inflammatory and immune response to titanium and polyethylene, a commonly used clinical material,  will be compared with methods such as quantitative real time polymerase chain reaction (qRT-PCR) for molecular and cellular mediators related gene expression and by histological examinations. In the next step similar implants will be coated with nano-structure impregnated with anti-inflammatory or/and immune suppressive components or with pro-inflammatory agents. Results will be correlated to those from the previous animal study and will hypothetically present a clear view on spatial and temporal roles of immunology and inflammation for the control of osseointegration/FBE. 

Project OfficerWennerberg, Ann
Co-InvestigatorTengvall, Pentti
Coordinating organisation
Malmö University
2016-01-01 - 2019-12-31
National Category
DiVA, id: project:2399

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